[1]冯慧,吴钟伟,刘超权.冠心病患者心率变异性指标与冠状动脉病变程度的关系[J].中国医学物理学杂志,2019,36(12):1472-1475.[doi:DOI:10.3969/j.issn.1005-202X.2019.12.021]
　FENG Hui,WU Zhongwei,LIU Chaoquan.Relationship between heart rate variability indexes and severity of coronary artery lesions in patients with coronary heart diseases[J].Chinese Journal of Medical Physics,2019,36(12):1472-1475.[doi:DOI:10.3969/j.issn.1005-202X.2019.12.021]
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冠心病患者心率变异性指标与冠状动脉病变程度的关系()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
36卷
期数:
2019年第12期
页码:
1472-1475
栏目:
医学生物物理
出版日期:
2019-12-25

文章信息/Info

Title:
Relationship between heart rate variability indexes and severity of coronary artery lesions in patients with coronary heart diseases
文章编号:
1005-202X（2019）12-1472-04
作者:
冯慧; 吴钟伟; 刘超权
海南西部中心医院心内科， 海南 儋州 571700
Author(s):
FENG Hui;  WU Zhongwei;  LIU Chaoquan
Department of Cardiology, West Central Hospital of Hai’nan Province, Danzhou 571700, China
关键词:
动态心电图; 冠心病; 心率变异性; 冠状动脉
Keywords:
Keywords: dynamic electrocardiogram;  coronary heart disease;  heart rate variability;  coronary artery
分类号:
R541.4
DOI:
DOI:10.3969/j.issn.1005-202X.2019.12.021
文献标志码:
A
摘要:
目的：探讨心率变异性指标与冠心病患者冠脉病变程度的关系。方法：选取冠心病患者84例（观察组），同时选取健康志愿者90例作为对照组，均给予24 h动态心电图监测。结果：观察组NN间期的标准差（SDNN）、RR间期的均值标准差（SDANN）、相邻RR间期差值的均方根（RMSSD）、相邻RR间期差值>50 ms的心搏数所占百分比（PMN50）和高频功率（HF）分别为（95.54±20.12） ms、（94.48±21.15） ms、（29.84±10.06） ms、（7.46±2.31）%和（0.85±0.20） Hz，明显低于对照组（P<0.05），而低频功率（LF）为（137.74±21.16） Hz，明显高于对照组（P<0.05）；冠状动脉病变≥3支患者SDNN、SDANN、RMSSD、PMN50和HF分别为（84.31±19.64） ms、（89.42±18.82） ms、（23.38±7.15） ms、（5.40±1.90）%和（0.70±0.21） Hz，明显低于冠状动脉病变数为1支和2支患者（P<0.05），而LF为（150.54±21.15） Hz，明显高于冠状动脉病变数为1支和2支患者（P<0.05）；观察组男女患者SDNN、SDANN、RMSSD、PMN50、HF和LF比较差异无统计学意义（P>0.05）；Gensini评分与SDNN、SDANN、RMSSD、PMN50、HF呈负相关（r=-0.511、-0.487、-0.543、-0.512和-0.507, P<0.05），与LF呈正相关（r=0.577, P<0.05）。结论：动态心电图在冠心病患者冠脉病变程度评价中有一定应用价值，其心率变异性指标与冠状动脉病变程度有一定关系。
Abstract:
Abstract: Objective To explore the relationship between heart rate variability indexes and the severity of coronary artery lesions in patients with coronary heart diseases. Methods Eighty-four patients with coronary heart diseases were selected as observation group, and 90 healthy volunteers were selected as control group. All subjects were given 24-hour dynamic electrocardiogram monitoring. Results The standard deviation of NN intervals (SDNN), standard deviation of averaged RR intervals (SDANN), square root of the mean squared differences of successive RR intervals (RMSSD), percentage of heartbeats with differences between adjacent RR interval >50 ms (PMN50) and high-frequency power (HF) of observation group were (95.54±20.12) ms, (94.48±21.15) ms, (29.84±10.06) ms, (7.46±2.31)% and (0.85±0.20) Hz, respectively, obviously lower than those of control group, while the low-frequency power (LF) of observation group was (137.74±21.16) Hz, which was significantly higher than that of control group (P<0.05). The SDANN, RMSSD, PMN50 and HF in patients with no less than 3 branches of coronary artery lesions were (84.31±19.64) ms, (89.42±18.82) ms, (23.38±7.15) ms, (5.40±1.90)% and (0.70±0.21) Hz, respectively, which were significantly lower than those in patients with less than 3 branches of coronary artery lesions (P<0.05), while LF was (150.54±21.15) Hz, significantly higher than those in patients with less than 3 branches of coronary artery lesions (P<0.05). There was no significant difference in SDNN, SDANN, RMSSD, PMN50, HF and LF between males and females in observation group (P>0.05). Gensini scores were negatively correlated with SDNN, SDANN, RMSSD, PMN50 and HF (r=-0.511, -0.487, -0.543, -0.512, -0.507; P<0.05), but positively correlated with LF (r=0.577, P<0.05). Conclusion Dynamic electrocardiogram has a certain application value in evaluating the severity of coronary artery lesions in patients with coronary heart diseases, and the heart rate variability indexes have a certain relationship with the severity of coronary artery lesions.

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备注/Memo

备注/Memo:
【收稿日期】2019-07-17 【基金项目】海南省自然科学基金（0113080033） 【作者简介】冯慧，主治医师，E-mail: hlb1978@126.com 【通信作者】吴钟伟，博士，副主任医师，E-mail: 13307665898@sina.cn
更新日期/Last Update: 2019-12-26