[1]张天龙,赵继荣,陈祁青,等.基于RS-fMRI功能连接分析方法探讨腰椎间盘突出症致慢性腰腿痛脑机制的研究进展[J].中国医学物理学杂志,2019,36(12):1421-1426.[doi:DOI:10.3969/j.issn.1005-202X.2019.12.011]
　ZHANG Tianlong,ZHAO Jirong,CHEN Qiqing,et al.Progress in RS-fMRI functional connection analysis-based research on brain mechanism of chronic low back and leg pain caused by lumbar disc herniation[J].Chinese Journal of Medical Physics,2019,36(12):1421-1426.[doi:DOI:10.3969/j.issn.1005-202X.2019.12.011]
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基于RS-fMRI功能连接分析方法探讨腰椎间盘突出症致慢性腰腿痛脑机制的研究进展()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
36卷
期数:
2019年第12期
页码:
1421-1426
栏目:
医学影像物理
出版日期:
2019-12-25

文章信息/Info

Title:
Progress in RS-fMRI functional connection analysis-based research on brain mechanism of chronic low back and leg pain caused by lumbar disc herniation
文章编号:
1005-202X（2019）12-1421-06
作者:
张天龙1; 赵继荣2; 陈祁青2; 马同2; 王闻奇3; 赵宁2; 薛旭1; 郭培尧1; 蔡毅1
1.甘肃中医药大学中医临床学院， 甘肃 兰州 730030； 2.甘肃省中医院， 甘肃 兰州 730050； 3.甘肃省中医院医学影像中心， 甘肃 兰州 730050
Author(s):
ZHANG Tianlong1;  ZHAO Jirong2;  CHEN Qiqing2;  MA Tong2;  WANG Wenqi3;  ZHAO Ning2;  XUE Xu1;  GUO Peiyao1;  CAI Yi1
1. School of Clinical Traditional Chinese Medicine, Gansu University of Chinese Medicine, Lanzhou 730030, China; 2. Gansu Provincial Hospital of TCM, Lanzhou 730050, China; 3. Medical Imaging Center, Gansu Provincial Hospital of TCM, Lanzhou 730050, China
关键词:
腰椎间盘突出症; 慢性腰腿痛; 静息态功能磁共振成像; 功能连接; 脑机制
Keywords:
Keywords: lumbar disc herniation;  chronic low back and leg pain;  resting-state functional magnetic resonance imaging;  brain mechanism
分类号:
R681.5；R319
DOI:
DOI:10.3969/j.issn.1005-202X.2019.12.011
文献标志码:
A
摘要:
【摘要】静息态功能磁共振成像（RS-fMRI）技术对阐释人类复杂脑网络提供了新媒介，尤其是在神经损伤脑机制分析方面取得了长足发展。腰椎间盘突出症（LDH）所致的慢性腰腿痛病变可引起大脑结构和功能的重塑。RS-fMRI技术对澄清大脑是如何参与慢性疼痛的调节机制方面发挥了重要作用，并有望为治疗LDH所致的慢性腰腿痛提供神经影像学指导。本文主要综述RS-fMRI脑功能连接分析方法在LDH所致的慢性疼痛中的最新应用进展，以期为临床治疗及研究LDH提供新思路。
Abstract:
Abstract: In recent years, resting-state functional magnetic resonance imaging (RS-fMRI) technology has provided a new medium for interpreting human complex brain networks, especially in the brain mechanism analysis of nerve injuries. Chronic low back and leg pain caused by lumbar disc herniation (LDH) will lead to the structural and functional remodeling of the brain. RS-fMRI technology plays an important role in clarifying how the brain participates in the regulation of chronic pain, and the technology is expected to provide neuroimaging guidance for the treatment of chronic low back and leg pain caused by LDH. Herein the latest application progresses of RS-fMRI brain function connection analysis methods in chronic pain caused by LDH are mainly reviewed so as to provide new ideas for the clinical treatment and research of LDH.

相似文献/References:

[1]陈文敏,肖玲玲,李慧慧,等. 单侧痛腰椎间盘突出症的表面肌电信号特征[J].中国医学物理学杂志,2017,34(10):1022.[doi:DOI:10.3969/j.issn.1005-202X.2017.10.011]
　[J].Chinese Journal of Medical Physics,2017,34(12):1022.[doi:DOI:10.3969/j.issn.1005-202X.2017.10.011]
[2]赵继荣,薛旭,袁毓喆,等.基于体素的磁共振形态学腰椎间盘突出症慢性下肢痛模型大鼠的实验研究[J].中国医学物理学杂志,2021,38(7):820.[doi:DOI:10.3969/j.issn.1005-202X.2021.07.006]
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[3]陈祁青,赵继荣,蔡毅,等.基于静息态功能磁共振形态学腰椎间盘突出症慢性下肢痛模型大鼠的实验研究[J].中国医学物理学杂志,2022,39(4):430.[doi:DOI:10.3969/j.issn.1005-202X.2022.04.007]
　CHEN Qiqing,ZHAO Jirong,CAI Yi,et al.Experimental study of chronic lower limb pain rats with lumbar disc herniation based on resting-state functional magnetic resonance morphology[J].Chinese Journal of Medical Physics,2022,39(12):430.[doi:DOI:10.3969/j.issn.1005-202X.2022.04.007]
[4]李兰,殷小丹,李旭雪,等.3D MERGE与3D SPACE STIR序列在腰椎间盘突出症检查中的应用比较[J].中国医学物理学杂志,2024,41(1):27.[doi:DOI:10.3969/j.issn.1005-202X.2024.01.004]
　LI Lan,YIN Xiaodan,LI Xuxue,et al.Application of 3D MERGE sequence versus 3D SPACE STIR sequence in the examination of lumbar disc herniation[J].Chinese Journal of Medical Physics,2024,41(12):27.[doi:DOI:10.3969/j.issn.1005-202X.2024.01.004]

备注/Memo

备注/Memo:
【收稿日期】2019-07-20 【基金项目】国家自然科学基金（81760877）；兰州市创新人才项目（2018-RC-99） 【作者简介】张天龙，在读硕士，研究方向：中医药防治脊柱慢性疼痛相关疾病，E-mail: z18993614654@163.com 【通信作者】赵继荣，硕士，博士生导师、主任医师，研究方向：中医药防治脊柱脊髓疾病，E-mail: Zhaojirong0709@163.com
更新日期/Last Update: 2019-12-26