[1]宋星慧,高静琳,唐开奖. 高频超声与双源CT筛查高尿酸血症患者早期关节病变的比较[J].中国医学物理学杂志,2019,36(8):929-932.[doi:DOI:10.3969/j.issn.1005-202X.2019.08.013]
　SONG Xinghui,GAO Jinglin,TANG Kaijiang. Comparison of high-frequency ultrasound and dual-source CT in screening for early joint lesions in patients with hyperuricemia[J].Chinese Journal of Medical Physics,2019,36(8):929-932.[doi:DOI:10.3969/j.issn.1005-202X.2019.08.013]
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 高频超声与双源CT筛查高尿酸血症患者早期关节病变的比较()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
36卷
期数:
2019年第8期
页码:
929-932
栏目:
医学影像物理
出版日期:
2019-08-26

文章信息/Info

Title:
 Comparison of high-frequency ultrasound and dual-source CT in screening for early joint lesions in patients with hyperuricemia
文章编号:
1005-202X（2019）08-0929-04
作者:
 宋星慧; 高静琳; 唐开奖
 柳州市工人医院/广西医科大学第四附属医院风湿免疫科， 广西 柳州 545005
Author(s):
 SONG Xinghui;  GAO Jinglin;  TANG Kaijiang
 Department of Rheumatology and Immunity, Liuzhou Workers’ Hospital/Fourth Affiliated Hospital of Guangxi Medical University, Liuzhou 545005, China
关键词:
高尿酸血症; 关节病变; 高频超声; 双源CT
Keywords:
 ; Keywords: hyperuricemia;  joint lesion;  high-frequency ultrasound;  dual-energy CT
分类号:
R589.7；R445
DOI:
DOI:10.3969/j.issn.1005-202X.2019.08.013
文献标志码:
A
摘要:
 目的：探讨高频超声（HFUS）和双源CT（DECT）筛查无症状高尿酸血症（AH）早期关节病变的价值。方法：对50例AH患者（共300个关节）分别进行HFUS和DECT检查，观察并比较AH患者尿酸盐结晶、骨侵蚀、关节积液、滑膜增厚等和病变部位的彩色多普勒表现。结果：在300个关节中，HFUS检查有13.00%（39/300）关节发现病变，而DECT检查有17.67%（53/300）关节发现病变，差异无统计学意义。HFUS检出晶体沉着 8.33%、骨侵蚀0.67%、关节腔积液6.67%，其中滑膜血管翳4.66%。通过DECT 检查发现晶体沉着16.33%、骨侵蚀3.67%、关节腔积液4.00%，不能检查出滑膜增生。DECT检出晶体沉着阳性率、骨侵蚀阳性率均高于HFUS检查且差异有统计学意义，而HFUS检出关节腔积液阳性率高于DECT检查且差异有统计学意义。结论：HFUS和DECT均可用于筛查AH早期关节病变，其中DECT检测尿酸盐结晶、骨侵蚀较HFUS更有优势，而HFUS发现早期关节腔积液及了解滑膜情况较DECT更有优势。
Abstract:
 Abstract: Objective To investigate the value of high-frequency ultrasound (HFUS) and dual-energy CT (DECT) in the screening for early joint lesions of asymptomatic hyperuricemia (AH). Methods Fifty patients with AH (with a total of 300 joints) were examined with HFUS and DECT. The urate crystal, bone erosion, joint effusion, synovial thickening and the color Doppler findings at lesions in patients with AH were observed and compared. Results Among the 300 joints, 13.00% (39/300) of the joints were found in the HFUS examination, and 17.67% (53/300) of the joints were found in the DECT detection. The positive rates of crystal deposition, bone erosion, joint effusion and synovial pannus detected with HFUS were 8.33%, 0.67%, 6.67% and 4.66%, respectively. The positive rates of crystal deposition, bone erosion and joint effusion detected with DECT were 16.33%, 3.67% and 4.00%, respectively, and synovial hyperplasia could not be detected with DECT. The positive rates of crystal deposition and bone erosion detected with DECT were higher than those detected with HFUS, and the differences were statistically significant. However, compared with DECT, HFUS achieved a higher positive rate of joint cavity effusion, and the difference was statistically significant. Conclusion Both HFUS and DECT can be used to screen the early joint lesions of AH. DECT is more advantageous than HFUS in detecting urate crystal and bone erosion. However, HFUS is superior to DECT in detecting the early joint effusion and understanding synovial membrane.

备注/Memo

备注/Memo:
 【收稿日期】2019-01-12
【基金项目】广西自治区卫计委科研课题（Z2015147）
【作者简介】宋星慧，副主任医师，主要研究方向：风湿免疫性疾病发病机制，E-mail: huihui3012@qq.com
更新日期/Last Update: 2019-08-26