磁共振灌注成像在高级别脑胶质瘤与单发脑转移瘤鉴别诊断中的价值-《中国医学物理学杂志》

文章信息/Info

Title:: Value of magnetic resonance perfusion imaging in the differential diagnosis of high-grade glioma and single brain metastasis

Author(s):: LIU Sheng; Department of Radiology, Guilin People’s Hospital, Guilin 541002, China

Keywords:: Keywords: magnetic resonance perfusion imaging; high-grade glioma; single brain metastasis; differential diagnosis

摘要:: 【摘要】目的：观察和分析磁共振灌注成像对高级别脑胶质瘤的诊断价值。方法：选取经病理证实的84例高级别脑胶质瘤患者和60例单发脑转移瘤患者，采用磁共振动态增强灌注成像，测算肿瘤实质区与瘤周水肿区的相对脑血容量（rCBV）值，并进行统计学分析。结果：高级别脑胶质瘤和单发脑转移瘤的时间-信号曲线不同。在肿瘤实质区，单发脑转移瘤的 rCBV值为4.03±0.79，低于高级别脑胶质瘤的5.48±1.32，差异有统计学意义（P<0.05）；瘤周水肿区，单发脑转移瘤的rCBV 值为0.74±0.35，低于高级别脑胶质瘤的1.48±0.26，差异有统计学意义（P<0.05）。结论：磁共振动态增强灌注成像在鉴别单发脑转移瘤和高级别脑胶质瘤中具有较高的临床价值。

Abstract:: Abstract: Objective To study and evaluate the diagnostic value of magnetic resonance perfusion imaging in high- grade glioma. Methods A total of 84 patients with pathologically confirmed high-grade glioma and 60 patients with single brain metastasis were enrolled in the study. Dynamic contrast- enhanced magnetic resonance perfusion imaging was used to measure the relative cerebral blood volume (rCBV) in tumor parenchyma and peritumor edema area, and a statistical analysis was conducted on the obtained data. Results The time-signal intensity curve of high-grade glioma was different from that of single brain metastasis. In tumor parenchyma, the rCBV of single brain metastasis was lower than that of high-grade glioma, with statistical significance (4.03±0.79 vs 5.48±1.32, P<0.05). In the edema area, the rCBV of single brain metastasis was 0.74±0.35, lower than 1.48±0.26 of high-grade glioma, and the difference was statistically significant (P<0.05). Conclusion Dynamic contrast-enhanced magnetic resonance perfusion imaging has a high clinical value in the differential diagnosis of single brain metastasis and high-grade glioma.