[1]任慧雅,高宏博,李月秋,等. 石墨烯热疗对良性甲状腺结节的疗效[J].中国医学物理学杂志,2019,36(4):487-491.[doi:DOI:10.3969/j.issn.1005-202X.2019.04.023]
　REN Huiya,GAO Hongbo,LI Yueqiu,et al. Therapeutic effects of graphene thermal therapy for benign thyroid nodules[J].Chinese Journal of Medical Physics,2019,36(4):487-491.[doi:DOI:10.3969/j.issn.1005-202X.2019.04.023]
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 石墨烯热疗对良性甲状腺结节的疗效()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
36卷
期数:
2019年第4期
页码:
487-491
栏目:
医学生物物理
出版日期:
2019-04-25

文章信息/Info

Title:
 Therapeutic effects of graphene thermal therapy for benign thyroid nodules
文章编号:
1005-202X（2019）04-0487-05
作者:
 任慧雅1; 高宏博2; 李月秋3; 李爱红1; 张桂玲1; 李静华4
 1.保定市第一医院内分泌科， 河北 保定 071000； 2.保定市第一中心医院心内科， 河北 保定 071000； 3.烯旺新材料科技股份有限公司， 广东 深圳 518057； 4.承德医学院中医学院治未病研究室， 河北 承德 067000
Author(s):
 REN Huiya1;  GAO Hongbo2;  LI Yueqiu3;  LI Aihong1;  ZHANG Guilin1;  LI Jinghua4
 1. Department of Endocrinology, Baoding No.1 Hospital, Baoding 071000, China; 2. Department of Cardiology, Baoding No.1 Central Hospital, Baoding 071000, China; 3. Grahope New Materials Technologies Inc., Shenzhen 518057, China; 4. Department of Preventive Medicine, School of Traditional Chinese Medicine, Chengde Medical College, Chengde 067000, China
关键词:
 ; 甲状腺结节; 石墨烯; 热疗; 最大直径; 最大横截面面积
Keywords:
 ; Keywords: thyroid nodule;  grapheme;  thermal therapy;  maximum diameter;  maximum cross-sectional area
分类号:
R312；R581
DOI:
DOI:10.3969/j.issn.1005-202X.2019.04.023
文献标志码:
A
摘要:
 目的：探讨石墨烯热疗对良性甲状腺结节的影响。方法：选取良性甲状腺结节患者97例，随机分为对照组（47例）和治疗组（50例），对照组不接受任何干预措施，治疗组接受4个疗程共120 d的石墨烯护颈带治疗。超声测量两组患者治疗前后甲状腺结节最大直径、最大横截面面积，并采用直接化学发光法检测治疗前后两组患者甲状腺功能（FT3、FT4和促甲状腺激素）。结果：对照组治疗前后甲状腺结节最大直径、最大横截面面积无明显变化（P>0.05）；经过治疗后，治疗组甲状腺结节最大直径减小（0.17±0.13） cm（P<0.05），最大横截面面积减小（0.41±0.45） cm2（P<0.05）。两组患者治疗前后甲状腺功能无明显变化（P>0.05）。结论：石墨烯热疗可缩小良性甲状腺结节的最大直径和最大横截面面积，对甲状腺功能无明显影响，具有良好的临床应用前景。
Abstract:
 Abstract: Objective To explore the responses of benign thyroid nodules to graphene thermal therapy. Methods A total of 97 patients with benign thyroid nodules were enrolled in this study and then randomly divided into control group (n=47) and treatment group (n=50). Control group did not receive any intervention measure, while treatment group received 4 courses (120 days) of graphene neck protection bandage treatment. The maximum diameter and maximum cross-sectional area of the thyroid nodules before and after treatment in both groups were measured with ultrasound. Thyroid functions (FT3, FT4 and thyroid stimulating hormone) in both groups before and after treatment were detected by direct chemiluminescence. Results The maximum diameter and maximum cross-sectional area of the thyroid nodules before and after treatment showed no obvious changes in control group (P>0.05). However, the maximum diameter and maximum cross-sectional area of the thyroid nodules in treatment group were reduced by (0.17±0.13) cm and (0.41±0.45) cm2, respectively (P<0.05). The hyroid functions remained stable in both groups before and after treatment (P>0.05). Conclusion Graphene thermal therapy which can reduce the maximum diameter and maximum cross-sectional area of benign thyroid nodules and has no significant effects on the thyroid functions is worthy of clinical application.

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备注/Memo

备注/Memo:
 【收稿日期】2018-11-11
【基金项目】保定市科学技术研究与发展指导计划（12ZF001）
【作者简介】任慧雅，硕士，主任中医师，研究方向：甲状腺疾病的诊治，E-mail: 783735141@qq.com
更新日期/Last Update: 2019-04-23