[1]夏丽坤,卢敏,罗佳,等. 子痫前期及子痫致可逆性后部脑病综合征的MRI表现[J].中国医学物理学杂志,2019,36(3):326-329.[doi:DOI:10.3969/j.issn.1005-202X.2019.03.016]
　XIA Likun,LU Min,LUO Jia,et al. MRI manifestations of posterior reversible encephalopathy syndrome in patients with preeclampsia and eclampsia[J].Chinese Journal of Medical Physics,2019,36(3):326-329.[doi:DOI:10.3969/j.issn.1005-202X.2019.03.016]
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 子痫前期及子痫致可逆性后部脑病综合征的MRI表现()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
36卷
期数:
2019年第3期
页码:
326-329
栏目:
医学影像物理
出版日期:
2019-03-25

文章信息/Info

Title:
 MRI manifestations of posterior reversible encephalopathy syndrome in patients with preeclampsia and eclampsia
文章编号:
1005-202X（2019）03-0326-04
作者:
 夏丽坤1; 卢敏2; 罗佳3; 张国兰1; 崔钰1; 马坚1
 1.玉溪市人民医院磁共振室， 云南 玉溪 653100； 2.玉溪市人民医院麻醉科， 云南 玉溪 653100； 3.玉溪市人民医院产科， 云南 玉溪 653100
Author(s):
 XIA Likun1;  LU Min2;  LUO Jia3;  ZHANG Guolan1;  CUI Yu1;  MA Jian1
 1. Department of Magnetic Resonance Imaging, People’s Hospital of Yuxi City, Yuxi 653100, China; 2. Department of Anesthesiology, People’s Hospital of Yuxi City, Yuxi 653100, China; 3. Department of Obstetrics, People’s Hospital of Yuxi City, Yuxi 653100, China
关键词:
 ; 子痫前期; 子痫; 可逆性后部脑病综合征; 磁共振成像
Keywords:
 ; Keywords: preeclampsia;  eclampsia;  posterior reversible encephalopathy syndrome;  magnetic resonance imaging
分类号:
R743.2；R445.2
DOI:
DOI:10.3969/j.issn.1005-202X.2019.03.016
文献标志码:
A
摘要:
 目的：探讨子痫前期及子痫致可逆性后部脑病综合征（PRES）的MRI及临床表现，提高对该病的认识和诊疗水平。方法：回顾性分析22例经临床证实为子痫前期及子痫致PRES患者的影像学和临床资料。结果：22例患者中3例为子痫前期，19例为子痫，主要临床表现为血压升高和头痛，癫痫发作、视觉障碍、精神异常等；MRI典型表现为双侧顶枕叶为主的血管源性水肿，T1为低或等信号，T2/FLAIR高信号，DWI为等或低信号，ADC为高信号。PRES病灶分布模式：顶枕型2例，全半球分水岭型9例，额上回型4例，部分或不对称型6例，中央变异型1例；21例患者住院治疗临床症状消失，预后良好，1例患者死亡。结论：子痫前期及子痫致PRES具有典型的临床和MRI表现，早期诊断可以提高预后和治疗效果。
Abstract:
 Abstract: Objective To investigate the magnetic resonance imaging (MRI) and clinical manifestations of posterior reversible encephalopathy syndrome (PRES) in patients with preeclampsia and eclampsia for improving the understanding of the disease and enhancing the levels of diagnosis and treatment. Methods The imaging and clinical data of 22 patients with preeclampsia and eclampsia combined with PRES were analyzed retrospectively. Results Among the 22 patients, 3 were preeclampsia and 19 were eclampsia. The main clinical manifestations included raised blood pressure, headache, seizures, visual impairment, mental abnormality, etc. The typical MRI image was characterized by vascular edema which was mainly located in bilateral parieto-occipital lobe. Moreover, the imaging manifestations also included isointense or hypointense signals on T1-weighted image, hyperintense signals on T2/FLAIR image, isointense or hypointense signals on diffusion weighted image, and hyperintense signals on apparent diffusion coefficient image. The distribution patterns of PRES lesions included parieto-occipital pattern in 2 cases, holohemispheric watered pattern in 9 cases, superior frontal gyrus pattern in 4 cases, partial or asymmetric pattern in 6 cases, and central-variant pattern in 1 case. After treatment, only 1 patient died. The clinical symptoms of the other 21 patients disappeared, and the prognoses were favorable. Conclusion PRES in patients with preeclampsia and eclampsia has typical clinical and MRI manifestations. The early diagnosis is helpful to improve the prognosis and therapeutic effect.

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备注/Memo

备注/Memo:
 【收稿日期】2018-10-26
【作者简介】夏丽坤，主治医师，主要从事磁共振诊断及功能磁共振研究，E-mail: xlk0315@163.com
更新日期/Last Update: 2019-03-26