[1]张夏静,夏天,何培忠.微焦点类同轴X射线相衬成像实验及相位恢复重建[J].中国医学物理学杂志,2018,35(9):1050-1055.[doi:10.3969/j.issn.1005-202X.2018.09.011]
　ZHANG Xiajing,XIA Tian,HE Peizhong.Micro-focus in-line X-ray phase contrast imaging experiment and phase recovery reconstruction[J].Chinese Journal of Medical Physics,2018,35(9):1050-1055.[doi:10.3969/j.issn.1005-202X.2018.09.011]
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微焦点类同轴X射线相衬成像实验及相位恢复重建()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
35卷
期数:
2018年第9期
页码:
1050-1055
栏目:
医学影像物理
出版日期:
2018-09-27

文章信息/Info

Title:
Micro-focus in-line X-ray phase contrast imaging experiment and phase recovery reconstruction
文章编号:
1005-202X（2018）09-1050-06
作者:
张夏静1; 夏天2; 何培忠3
1. 上海理工大学医疗器械与食品学院，上海200093；2. 华东师范大学磁共振重点实验室，上海200062；3. 上海健康医学院，上海 201318
Author(s):
ZHANG Xiajing1;  XIA Tian2;  HE Peizhong3
1. School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China; 2. Key Laboratory of Magnetic Resonance, East China Normal University, Shanghai 200062, China; 3. Shanghai University of Medicine & Health Sciences, Shanghai 201318, China
关键词:
X射线; 相位衬度成像; 微焦点; 边缘增强; 相位提取
Keywords:
Keywords: X-ray;  phase contrast imaging;  micro-focus;  edge enhancement;  phase extraction
分类号:
R312；TP434
DOI:
10.3969/j.issn.1005-202X.2018.09.011
文献标志码:
A
摘要:
目的：基于微焦点X射线源，进行相衬成像实验和相位信息提取。方法：根据Fresnel-Kirchhoff衍射理论，考虑 空间相干性与时间相干性的影响，对连续X射线相衬成像的一般公式进行推导。根据从含有相位信息和吸收信息的图片 里提取纯相位信息的方法，通过MATLAB对相衬图片进行处理。结果：实验一，对塑料吸管进行相衬成像，通过改变探 测器与样品之间的距离，得到比传统X射线成像更清晰、放大且能够突出边界信息的图像；实验二，在电压分别为45 kVp 和70 kVp的情况下得到硼硅酸盐玻璃的相衬图像，然后通过相位恢复重建得到含有纯相位信息的相衬图像。结论：对于 轻元素物质，微焦点类同轴X射线相衬成像比传统X射线相衬成像的分辨率高、图像衬度好；相位信息提取技术将会大大 促进微焦点类同轴X射线相衬成像技术在普通实验室应用和医学肿瘤检测等方面的应用进展。
Abstract:
Abstract: Objective To perform phase contrast imaging experiment and phase information extraction based on micro-focus Xray source. Methods Based on Fresnel-Kirchhoff diffraction theory and considering the effects of spatial coherence and temporal coherence, the general formula of continuous X-ray phase contrast imaging was derived. According to the method of extracting pure phase information from the images containing phase information and absorption information, the phase contrast images were processed with MATLAB. Results In experiment 1, phase contrast imaging was conducted on a plastic straw. By changing the distance between the detector and the sample, the images which were clearer and larger than those obtained by traditional X-ray imaging and highlighted the boundary information were obtained. In experiment 2, the phase contrast images of borosilicate glass at tube voltage of 45 kVp and 70 kVp were obtained and then the phase contrast images containing pure phase information were obtained through phase recovery reconstruction. Conclusion For light elements, micro-focus in-line X-ray phase contrast imaging is superior to traditional X-ray phase contrast imaging in image resolution and image contrast. The technology of phase information extraction will greatly promote the applications of X-ray phase contrast imaging in general laboratory and clinical tumor detection.

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备注/Memo

备注/Memo:
【收稿日期】2018-03-22 【作者简介】张夏静，硕士研究生，研究方向：生物医学仪器及医学信 息技术，E-mail: 26751453@qq.com 【通信作者】何培忠，博士，教授，研究方向：医学影像设备，E-mail: hepz@sumhs.edu.cn
更新日期/Last Update: 2018-09-28