[1]滕建建,石锦平,张利文,等. 鼻咽癌容积调强剂量验证与计划复杂性的相关性[J].中国医学物理学杂志,2018,35(7):781-784.[doi:DOI:10.3969/j.issn.1005-202X.2018.07.008]
 TENG Jianjian,SHI Jinping,ZHANG Liwen,et al. Correlation between dose verification and plan complexity of volumetric modulated arc therapy for nasopharyngeal carcinoma[J].Chinese Journal of Medical Physics,2018,35(7):781-784.[doi:DOI:10.3969/j.issn.1005-202X.2018.07.008]
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 鼻咽癌容积调强剂量验证与计划复杂性的相关性()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
35卷
期数:
2018年第7期
页码:
781-784
栏目:
医学放射物理
出版日期:
2018-07-20

文章信息/Info

Title:
 Correlation between dose verification and plan complexity of volumetric modulated arc therapy for nasopharyngeal carcinoma
文章编号:
1005-202X(2018)07-0781-04
作者:
 滕建建石锦平张利文谢秋英刘致滨
 佛山市第一人民医院/中山大学附属佛山医院肿瘤中心放疗科, 广东 佛山 528000
Author(s):
 TENG Jianjian SHI Jinping ZHANG Liwen XIE Qiuying LIU Zhibin
 Department of Radiation Oncology, Cancer Center, the First People’s Hospital of Foshan/Affiliated Foshan Hospital of Sun Yat-sen University, Foshan 528000, China
关键词:
 鼻咽癌容积调强放疗调强复杂性指数剂量验证
Keywords:
 : nasopharyngeal carcinoma volumetric modulated arc therapy modulation complexity score dose verification
分类号:
R815.6;R739.6
DOI:
DOI:10.3969/j.issn.1005-202X.2018.07.008
文献标志码:
A
摘要:
 目的:研究鼻咽癌容积调强剂量验证γ通过率与计划复杂性之间的相关性。 方法:选取106例鼻咽癌容积调强计划,采用二维电离室矩阵Matrixx进行剂量验证,比较测量的和计划的剂量分布,评价在不同标准(3%/3 mm、3%/2 mm、3%/1 mm、2%/2 mm)下的通过率。采用调强复杂性指数(MCS)定量评价计划的复杂性,并分析计划验证γ通过率与MCS间的关系。 结果:鼻咽癌容积调强计划在3%/3 m、3%/2 mm、3%/1 mm、2%/2 mm标准下的通过率分别为(98.49±0.95)%、(95.92±1.71)%、(89.74±2.44)%、(90.58±2.87)%。计划的平均MCS值为0.210±0.019,与通过率间(3%/3 m、3%/2 mm、3%/1 mm、2%/2 mm标准)的Pearson相关性系数分别为0.333(P<0.001)、0.303(P=0.002)、0.347(P<0.001)、0.267(P=0.006)。 结论:鼻咽癌容积调强计划验证γ通过率与MCS之间有相关性,但相关性较弱。
Abstract:
 Objective To study the correlations between gamma passing rate in dose verification and plan complexity of volumetric modulated arc therapy (VMAT) of nasopharyngeal carcinoma (NPC). Methods The VMAT plans of 106 NPC patients were selected. A two-dimensional ionization chamber array Matrixx was used for dose verification. The measured and planned dose distributions were compared and the gamma passing rates were evaluated under different criteria (3%/3 mm, 3%/2 mm, 3%/1 mm and 2%/2 mm). The modulation complexity score (MCS) of the treatment plan was calculated and used to quantitatively evaluate plan complexity. The correlation analysis between gamma passing rate and plan complexity was performed. Results If using the criteria of 3%/3 mm, 3%/2 mm, 3%/1 mm and 2%/2 mm, the gamma passing rate of VMAT plans was (98.49±0.95)%, (95.92±1.71)%, (89.74±2.44)% and (90.58±2.87)%, respectively. The mean MCS of plans was 0.210±0.019. Pearson’s correlation coefficient between the gamma passing rate (3%/3 mm, 3%/2 mm, 3%/1 mm and 2%/2 mm) and MCS were 0.333 (P<0.001), 0.303 (P=0.002), 0.347 (P<0.001) and 0.267 (P=0.006), respectively. Conclusion The gamma passing rate in the dose verification showed a weak correlation with MCS of VMAT of NPC.

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备注/Memo

备注/Memo:
 【收稿日期】2018-01-13
【作者简介】滕建建,硕士,主管技师,研究方向:放射治疗计划设计及物理质量控制,E-mail: deartjj@163.com
【通信作者】石锦平,主任技师,研究方向:肿放射治疗计划设计及物理质量控制,E-mail: rath55@126.com
更新日期/Last Update: 2018-07-24