[1]周晖,许赪,沈文同,等. 左乳癌保乳术后调强放疗计划三维剂量验证[J].中国医学物理学杂志,2017,34(12):1216-1119.[doi:DOI:10.3969/j.issn.1005-202X.2017.12.006]
 ZHOU Hui,XU Cheng,SHEN Wentong,et al. Three-dimensional dose verification of intensity-modulated radiotherapy after left breast-conserving surgery[J].Chinese Journal of Medical Physics,2017,34(12):1216-1119.[doi:DOI:10.3969/j.issn.1005-202X.2017.12.006]
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 左乳癌保乳术后调强放疗计划三维剂量验证()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
34卷
期数:
2017年第12期
页码:
1216-1119
栏目:
医学放射物理
出版日期:
2017-12-20

文章信息/Info

Title:
 Three-dimensional dose verification of intensity-modulated radiotherapy after left breast-conserving surgery
文章编号:
1005-202X(2017)12-1216-04
作者:
 周晖许赪沈文同陈毅张毅斌
 上海交通大学医学院附属瑞金医院, 上海 200025
Author(s):
 ZHOU Hui XU Cheng SHEN Wentong CHEN Yi ZHANG Yibin
 Ruijin Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai 200025, China
关键词:
 乳腺癌调强放疗三维剂量验证Compass系统
Keywords:
 breast cancer intensity-modulated radiotherapy three-dimensional dose verification Compass system
分类号:
R811.1
DOI:
DOI:10.3969/j.issn.1005-202X.2017.12.006
文献标志码:
A
摘要:
 【摘 要】 放疗计划验证能够确保病人接受精准治疗,具有重要临床意义。选取11例左乳癌保乳术后患者,对其调强放疗计划做Compass三维剂量验证。通过Compass重建计划与Pinnacle治疗计划系统数据对比,分析靶区(Planning Target Volume, PTV)和危及器官(Organs-at-Risk, OAR)的剂量体积直方图与Gamma值。PTV和OAR的[D1]、[D95]、[D99]、[Dmean]偏差小于1 Gy,[V5]、[V20]、[V30]偏差小于1.5%。在3 mm/3%标准下,PTV平均Gamma值为0.45±0.04,通过率均值为92.70%±2.44%,且具有统计学意义;OAR通过率接近100%。在2 mm/2%标准下,PTV通过率均值为78.61%±3.90%;OAR通过率均值为97.34%±0.96%。Compass验证了直线加速器对放疗计划的执行能力,为乳腺癌保乳术后调强放疗计划的临床应用提供了依据。
Abstract:
 Abstract: Radiotherapy planning verification can ensure that patients receive accurate treatment. We performed Compass three-dimensional dose verification for intensity-modulated radiotherapy (IMRT) plans for 11 patients undergoing breast-conserving surgery for left breast cancer. The dose-volume histograms and Gamma values of the planning target volume (PTV) and the organs-at-risk (OAR) were analyzed by comparing the parameters in Compass reconstruction plan with those in Pinnacle treatment planning system. The results showed that the deviation of[ D1], [D95], [D99], and[ Dmean] of PTV and OAR were less than 1 Gy, and that of [V5, V20]and[ V30] were less than 1.5%. Under the 3 mm/3% criterion, the average Gamma value of PTV was 0.45±0.04, and the average passing rate was 92.70%±2.44%, which had a statistical significance; for OAR, the passing rate was nearly 100%. Under the 2 mm/2% criterion, the mean passing rate of PTV was 78.61%±3.90%, and that of OAR was 97.34%±0.96%. Compass is capable of verifying the feasibility of linear accelerator in radiotherapy planning to facilitate the clinical implementation of radiotherapy plans after breast-conserving surgery for breast cancer.

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备注/Memo

备注/Memo:
 【收稿日期】2017-10-17
【作者简介】周晖,男,硕士,初级物理师,研究方向:医学物理,E-mail: zhouhui2012@yeah.net
【通信作者】许赪,男,博士,副主任医师,研究方向:乳腺癌、前列腺癌放射治疗,E-mail:xucheng60@126.com
更新日期/Last Update: 2017-12-20