[1]张少丹,李兵,陈薇. 超声弹性成像鉴别诊断肝脏良恶性肿瘤的准确性及其影响因素分析[J].中国医学物理学杂志,2018,35(7):807-810.[doi:DOI:10.3969/j.issn.1005-202X.2018.07.013]
　ZHANG Shaodan,LI Bing,CHEN Wei. Accuracy of ultrasound elastography in differential diagnosis of benign and malignant liver tumors and analysis of its influencing factors[J].Chinese Journal of Medical Physics,2018,35(7):807-810.[doi:DOI:10.3969/j.issn.1005-202X.2018.07.013]
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 超声弹性成像鉴别诊断肝脏良恶性肿瘤的准确性及其影响因素分析()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
35卷
期数:
2018年第7期
页码:
807-810
栏目:
医学影像物理
出版日期:
2018-07-20

文章信息/Info

Title:
 Accuracy of ultrasound elastography in differential diagnosis of benign and malignant liver tumors and analysis of its influencing factors
文章编号:
1005-202X（2018）07-0807-04
作者:
 张少丹1; 李兵2; 陈薇1
 1.西安工会医院超声科， 陕西 西安710100； 2.西安工会医院普外科， 陕西 西安 710100
Author(s):
 ZHANG Shaodan1;  LI Bing2;  CHEN Wei1
 1. Department of Ultrasound, Xi’an Union Hospital, Xi’an 710100, China; 2. Department of General Surgery, Xi’an Union Hospital, Xi’an 710100, China
关键词:
 ; 肝脏肿瘤; 超声弹性成像; 造影剂; 灵敏度; 特异度
Keywords:
 ; Keywords: liver tumor;  ultrasound elastography;  contrast agent;  sensitivity;  specificity
分类号:
R455.1；R735.7
DOI:
DOI:10.3969/j.issn.1005-202X.2018.07.013
文献标志码:
A
摘要:
 目的：探讨超声弹性成像鉴别诊断肝脏良恶性肿瘤的准确性及其影响因素。 方法：选取疑似肝脏肿瘤患者共186例，其中采用超声进行诊断共计56例，超声弹性成像诊断共计77例，超声联合造影剂诊断共计53例。根据不同的诊断方法分为A、B、C 3组，以病理诊断结果为金标准，对比3组诊断结果的准确率、灵敏度和特异度，并建立回归模型对超声弹性成像鉴别诊断的影响因素进行分析。 结果：B、C组检测方法的灵敏性、特异性和准确性均优于A组，但B、C两组之间的灵敏性、特异性和准确性无显著差异；B、C组检测方法的总体效能均大幅高于A组，但B、C两组之间的效能无显著差异；肿瘤尺寸、钙化、血流情况、病灶软硬情况均对超声弹性成像鉴别诊断有一定的影响，但肿瘤尺寸、钙化及血流情况的影响程度较为轻微，病灶软硬情况影响较为显著。 结论：超声弹性成像鉴别诊断肝脏良恶性肿瘤具备较高的效能，而且能够大幅降低患者的治疗成本，值得在临床上进行推广。
Abstract:
 Abstract: Objective To investigate the accuracy and influencing factors of differential diagnosis of benign and malignant liver tumors with ultrasound elastography. Methods A total of 186 cases with suspected liver cancer were selected, including 56 cases diagnosed with ultrasound (group A), 77 diagnosed with ultrasound elastography (group B), and 53 diagnosed with ultrasound combined with contrast agent (group C). Using the diagnostic results on the medical records as the gold standards, the accuracy, sensitivity and specificity of the 3 groups were compared. Then a regression model was established to analyze the factors affecting the differential diagnosis of ultrasonic elastography. Results Group B and C were superior to group A in the sensitivity, specificity and accuracy of diagnosis, but no significant differences were found between group B and C. The overall efficacy in group B and C were significantly higher than that in group A, but group B and C didn’t showed any significant differences. The tumor size, calcification, blood flow, and the softness/hardness of the lesions had some effects on the differential diagnosis of ultrasonic elastography. The impacts of tumor size, calcification and blood flow were relatively mild, while the effects of the softness/hardness of the lesions were more significant. Conclusion Ultrasound elastography has a high efficacy in the differential diagnosis of benign and malignant liver tumors and greatly reduces the cost of treatment, worthy of clinical promotion.

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备注/Memo

备注/Memo:
 【收稿日期】2018-01-18
【作者简介】张少丹，副主任医师，研究方向：腹部超声，E-mail:4097872@qq.com；李兵，主任医师，研究方向：肝胆外科，E-mail:735754562@qq.com
【通信作者】陈薇，副主任医师，研究方向：腹部超声，E-mail:85138662@qq.com
更新日期/Last Update: 2018-07-24