[1]高鹏,罗奇志,魏良,等. 一次性使用输血器管路弹性对输液泵输注精度的影响[J].中国医学物理学杂志,2018,35(1):83-88.[doi:DOI:10.3969/j.issn.1005-202X.2018.01.015]
　GAO Peng,LUO Qizhi,WEI Liang,et al. Effects of elasticity of disposable blood transfusion set on precision of infusion pump[J].Chinese Journal of Medical Physics,2018,35(1):83-88.[doi:DOI:10.3969/j.issn.1005-202X.2018.01.015]
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 一次性使用输血器管路弹性对输液泵输注精度的影响()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
35卷
期数:
2018年第1期
页码:
83-88
栏目:
医学信号处理与医学仪器
出版日期:
2018-02-07

文章信息/Info

Title:
 Effects of elasticity of disposable blood transfusion set on precision of infusion pump
文章编号:
1005-202X（2018）01-0083-06
作者:
 高鹏1; 罗奇志2; 魏良1; 原莉莉2; 曾庆玲2; 李永勤1
 1.第三军医大学生物医学工程学院， 重庆 400038； 2.第三军医大学西南医院烧伤研究所， 重庆 400038
Author(s):
 GAO Peng1;  LUO Qizhi2;  WEI Liang1;  YUAN Lili2;  ZENG Qingling2;  LI Yongqin1
 1. School of Biomedical Engineering, Third Military Medical University, Chongqing 400038, China; 2. Burn Research Institute, Southwest Hospital Affiliated to Third Military Medical University, Chongqing 400038, China
关键词:
 ; 一次性使用输血器; 输液泵; 液体复苏; 输注相对误差; 弹性系数
Keywords:
 ; Keywords: disposable blood transfusion set;  infusion pump;  fluid resuscitation;  infusion relative error;  elastic coefficient
分类号:
R472
DOI:
DOI:10.3969/j.issn.1005-202X.2018.01.015
文献标志码:
A
摘要:
 目的：研究一次性使用输血器管路弹性对输液泵输注精度的影响，探讨提高输液泵输注精度的办法。 方法：选取市场常见的6种一次性使用输血器各4套，利用螺丝旋进法测量各输血器管路的弹性系数。利用晶体和胶体作为测试液体对每种输血器在输注速度设置为50、100、200、400 mL/h时的实际输注量进行测量，采用晶体测试时连续测量12 h，采用胶体测试时测量1 h，所有测试均在室温25 ℃下重复两轮。利用测试结果计算输注相对误差，并分析输注相对误差与弹性系数、设置速度、输注时间的关系。 结果：输血器管路弹性系数均值在1.64~3.75 N/mm之间。测试液体为晶体时各输血器输注相对误差均值介于-25.39%~9.93%之间，各输血器输注相对误差均值与弹性系数之间的相关系数为-0.934（P=0.006）；输注时间对输注相对误差无显著影响（P=0.624），不同测量时间下设置速度对输注相对误差有显著影响（P=0.000），弹性系数对输注相对误差有显著影响（P=0.000）；各输血器输注相对误差与设置速度的相关系数分别为-0.993（P=0.007）、-0.940（P=0.060）、-0.954（P=0.046）、-0.981（P=0.019）、-0.698（P=0.302）、-0.953（P=0.047）；各输血器输注相对误差与输注时间的相关系数分别为-0.950（P=0.000）、-0.799（P=0.002）、-0.777（P=0.003）、-0.414（P=0.181）、-0.917（P=0.000）、-0.677（P=0.016）；经逐步回归得回归方程：输注相对误差=0.464-0.001×设置速度-0.149×弹性系数，回归效果检验的F=696.908（P=0.000）。测试液体为胶体时各输血器输注相对误差均值介于-24.04%~10.49%之间，各输血器输注相对误差均值与弹性系数之间的相关系数为-0.918（P=0.010）；弹性系数对输注相对误差有显著影响（P=0.000），设置速度对输注相对误差有显著影响（P=0.000）；各输血器输注相对误差与设置速度的相关系数分别为-0.967（P=0.033）、-0.919（P=0.081）、-0.945（P=0.055）、-0.970（P=0.030）、
-0.710 （P=0.290）、-0.964（P=0.036）；经逐步回归得回归方程：输注相对误差=0.459-0.001×设置速度-0.137×弹性系数，回归效果检验的F=42.628（P=0.000）。 结论：一次性使用输血器在输液泵上使用时，影响输注精度的最主要因素是输血器的管路弹性，弹性系数增大输注相对误差减小。此外，输液泵设置速度也会影响输注精度，设置速度增大时输注相对误差减小，输注时间对输注精度影响不显著但部分输血器二者之间呈负相关。
Abstract:
Abstract: Objective To discuss the effect of elasticity of disposable blood transfusion set on precision of infusion pump, and investigate the method to improve the precision of infusion pump using disposable blood transfusion set. Methods Four sets of each 6 kinds of disposable blood transfusion sets were selected, and the elastic coefficient of each disposable blood transfusion set was measured. Under room temperature of 25 ℃, each disposable blood transfusion set was tested twice with the infusion rate of 50, 100, 200, 400 mL/h for 12 h (using crystal as testing fluid) and 1 h (using colloid as testing fluid), respectively, and the actual infusion rate was recorded per hour. The infusion relative error was calculated and the relationships between infusion relative error and elastic coefficient, setting infusion rate and infusion time were analyzed. Results The mean value of elastic coefficients of disposable blood transfusion set ranged from 1.64 N/mm to 3.75 N/mm. When crystal was used as testing fluid, the mean value of infusion relative error ranged from -25.39% to 9.93%. The correlation coefficient between elastic coefficient and infusion relative error was -0.934 (P=0.006). The effects of infusion time on infusion relative error were trivial (P=0.624). However, both setting infusion rate and elastic coefficient had significant effects on infusion relative error (P=0.000, 0.000). The correlation coefficients of each disposable blood transfusion set between infusion relative error and setting infusion rate were
-0.993, -0.940, -0.954, -0.981, -0.698 and -0.953, respectively (P=0.007, 0.060, 0.046, 0.019, 0.302, 0.047, respectively); the correlation coefficients between infusion relative error and infusion time were -0.950, -0.799, -0.777, -0.414, -0.917 and -0.677, respectively (P=0.000, 0.002, 0.003, 0.181, 0.000, 0.016, respectively). Based on the above mentioned data, the obtained regression equation was as follow: infusion relative error=0.464-0.001×setting infusion rate -0.149×elastic coefficient, of this regression, F=696.908 (P=0.000). When colloid was used as testing fluid, the mean value of infusion relative error ranged from -24.04% to 10.49%, and the correlation coefficient between infusion relative error and elastic coefficient was -0.918 (P=0.010). Both elastic coefficient and setting infusion rate had remarkable effects on infusion relative error (P=0.000, 0.000). With colloid as testing fluid, the correlation coefficient of each disposable blood transfusion set between infusion relative error and infusion time were -0.967, -0.919, -0.945, -0.970, -0.710 and -0.964, respectively (P=0.033, 0.081, 0.055, 0.030, 0.290, 0.036, respectively), and the obtained regression equation was as follow: infusion relative error=0.459-0.001×setting infusion rate -0.137×elastic coefficient, of this regression, F=42.628 (P=0.000). Conclusion When the disposable blood transfusion set was used on infusion pump, the most important factor affecting infusion precision is the elasticity of the transfusion set. With the increase of elastic coefficient, the infusion relative error was decreased. In addition, infusion precision is also affected by setting infusion rate, and the infusion relative error was declined with the increase of setting infusion rate. The infusion time had no significant effect on infusion accuracy but the infusion relative error of some the blood transfusion sets are negatively correlated with infusion time.

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备注/Memo

备注/Memo:
 【收稿日期】2017-07-17
【基金项目】陆军军医大学（第三军医大学）第一附属医院军事医学与战创伤救治临床新技术计划（SWH2016YSCXZD-11）
【作者简介】高鹏，硕士，技师，主要从事生物医学电子与信息技术研究，E-mail: gaopeng_xs@163.com
【通信作者】李永勤，博士，教授，主要从事生物医学信号检测处理、现代医学仪器关键技术研究，E-mail: leeoken@gmail.com
更新日期/Last Update: 2018-01-25