[1]马国强,郭丽,胡玮,等.双低扫描技术联合迭代重建算法在急性脑梗死患者CTP检查中的应用[J].中国医学物理学杂志,2025,42(9):1169-1173.[doi:DOI:10.3969/j.issn.1005-202X.2025.09.007]
　MA Guoqiang,GUO Li,HU Wei,et al.Application of dual-low scanning technology combined with iterative reconstruction algorithm in CTP examination of patients with acute cerebral infarction[J].Chinese Journal of Medical Physics,2025,42(9):1169-1173.[doi:DOI:10.3969/j.issn.1005-202X.2025.09.007]
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双低扫描技术联合迭代重建算法在急性脑梗死患者CTP检查中的应用()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
42
期数:
2025年第9期
页码:
1169-1173
栏目:
医学影像物理
出版日期:
2025-09-30

文章信息/Info

Title:
Application of dual-low scanning technology combined with iterative reconstruction algorithm in CTP examination of patients with acute cerebral infarction
文章编号:
1005-202X（2025）09-1169-05
作者:
马国强1; 郭丽1; 胡玮2; 杜玥蒙3
1.甘肃省第二人民医院介入导管室， 甘肃 兰州 730000； 2.甘肃省第二人民医院介入科， 甘肃 兰州 730000； 3.甘肃省第二人民医院放射影像科， 甘肃 兰州 730000
Author(s):
MA Guoqiang1;  GUO Li1;  HU Wei2;  DU Yuemeng3
1. Interventional Catheterisation Laboratory, Gansu Second Peoples Hospital, Lanzhou 730000, China 2. Department of Interventional Medicine, Gansu Second Peoples Hospital, Lanzhou 730000, China 3. Department of Radiological Imaging, Gansu Second Peoples Hospital, Lanzhou 730000, China
关键词:
急性脑梗死; 低浓度对比剂; 低管电压; 迭代重建技术; CT灌注
Keywords:
Keywords: acute cerebral infarction low-concentration contrast agent low tube voltage iterative reconstruction technique computed tomography perfusion
分类号:
R318；R816.1
DOI:
DOI:10.3969/j.issn.1005-202X.2025.09.007
文献标志码:
A
摘要:
目的：探讨双低扫描技术联合迭代重建技术（IR）在急性脑梗死（ACI）患者计算机断层扫描灌注（CTP）中的应用。方法：回顾性选取2018年12月~2022年12月在甘肃省第二人民医院确诊为ACI的120例患者，均接受CTP检查，根据CTP对比剂、管电压，分为双低组（n=64，低浓度对比剂-碘含量270 mgI/mL、低管电压80 kV）和对照组（n=56，常规浓度对比剂-碘含量350 mgI/mL、管电压120 kV），比较两组患者图像质量，应用组内相关系数评估图像质量的一致性；比较两组辐射剂量、碘佛醇注射液摄入量、大脑中动脉M1段CT值、信噪比（SNR）、对比噪声比（CNR）。结果：双低组与对照组的CTP图像质量无统计学差异（P>0.05）；双低组有效辐射剂量、剂量长度乘积等辐射剂量参数均低于对照组（P<0.05）；双低组碘佛醇注射液摄入量低于对照组（P<0.05）；双低组与对照组大脑中动脉M1段CT值、SNR、CNR比较，均无统计学差异（P>0.05）。结论：采用低浓度对比剂、低管电压联合IR扫描ACI患者，可在保障CTP图像质量的基础上，降低对比剂摄入量及辐射剂量。
Abstract:
Abstract: Objective To explore the application of low-concentration contrast agent and low tube voltage (dual-low) scanning technology combined with iterative reconstruction technique in computed tomography perfusion (CTP) scanning for patients with acute cerebral infarction (ACI). Methods A retrospective analysis was conducted on 120 patients diagnosed with ACI at Gansu Second Peoples Hospital from December 2018 to December 2022. All patients underwent CTP examination, and according to CTP contrast agent and tube voltage, they were divided into dual-low group (n=64, low-concentration contrast agent with an iodine content of 270 mgI/mL, low tube voltage of 80 kV) and control group (n=56, conventional concentration contrast agent with an iodine content of 350 mgI/mL, standard tube voltage of 120 kV). Images quality was compared between two groups, with the intraclass correlation coefficient used to evaluate the consistency of image quality. The radiation dose, intake of ioversol injection, CT value at M1 segment of the middle cerebral artery, signal-to-noise ratio, and contrast-to-noise ratio were also compared between two groups. Results The difference in CTP image quality between dual-low group and control group was trivial (P>0.05). The dual-low group exhibited lower dose-length product, effective radiation dose, and intake of ioversol injection than control group (P<0.05). No significant differences were observed in CT value at M1 segment of the middle cerebral artery, signal-to-noise ratio or contrast-to-noise ratio between two groups (P>0.05). Conclusion The application of dual-low scanning technology combined with iterative reconstruction algorithm can reduce intake of contrast agent and radiation dose while ensuring CTP images quality in ACI patients.

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备注/Memo

备注/Memo:
【收稿日期】2025-03-21 【基金项目】甘肃省科技计划项目（24JRRA1159） 【作者简介】马国强，副主任技师，研究方向：介入检查，E-mail: mgq857@163.com 【通信作者】郭丽，副主任护师，研究方向：介入检查，E-mail: 529382279@qq.com
更新日期/Last Update: 2025-09-30