[1]邵剑辉,杨鑫,李雅宁.腹压板不同压腹位置对肝癌立体定向放射治疗精度的影响[J].中国医学物理学杂志,2023,40(9):1064-1068.
　SHAO Jianhui,YANG Xin,LI Yaning.Effects of different abdominal compression plate positions on accuracy in stereotactic body radiotherapy for liver cancer[J].Chinese Journal of Medical Physics,2023,40(9):1064-1068.
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腹压板不同压腹位置对肝癌立体定向放射治疗精度的影响()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
40卷
期数:
2023年第9期
页码:
1064-1068
栏目:
医学放射物理
出版日期:
2023-09-26

文章信息/Info

Title:
Effects of different abdominal compression plate positions on accuracy in stereotactic body radiotherapy for liver cancer
文章编号:
1005-202X（2023）09-1064-05
作者:
邵剑辉; 杨鑫; 李雅宁
中山大学肿瘤防治中心放疗科/华南肿瘤学国家重点实验室/肿瘤医学协同创新中心， 广东 广州 510060
Author(s):
SHAO Jianhui;  YANG Xin;  LI Yaning
State Key Laboratory of Oncology in South China/Collaborative Innovation Center for Cancer Medicine/Department of Radiation Oncology of Sun Yat-Sen University Cancer Center, Guangzhou 510060, China
关键词:
肝癌; 立体定向放射治疗; 腹压板位置; 呼吸运动; 摆位误差
Keywords:
Keywords: liver cancer stereotactic body radiotherapy abdominal compression plate position respiratory movement setup error
分类号:
R816.5
文献标志码:
A
摘要:
目的：探究肝癌立体定向放射治疗中腹压板在不同位置施压对摆位误差及肿瘤移动度的影响。方法：选取经病理诊断为肝癌的患者共30例，根据腹压板施压位置不同分为腹压组和剑突组各15例。获取30例肝癌患者共180组4D-CBCT扫描数据，记录并分析每组内摆位误差大小，并利用Elekta直线加速器自带的XVI（X线容积影像系统）软件分析肿瘤随肝脏的移动度。结果：剑突组在Y方向上的摆位误差小于腹压组（P<0.05）。剑突组的肿瘤移动度均值在Y方向上小于腹压组（P<0.05），但在X和Z方向上差异无统计学意义（P>0.05）；剑突的肿瘤移动度均方差在Z方向上小于腹压组（P<0.05），但在X和Y方向上差异无统计学意义（P>0.05）；剑突组的肿瘤最大移动度在X和Y方向上小于腹压组（P<0.05），但在Z方向上差异无统计学意义（P>0.05）。剑突组在3个方向上的靶区外放边界值均比腹压组小。结论：在肝癌立体定向放射治疗中，腹压板压迫在剑突下位置比腹部肚脐位置的呼吸抑制效果更为明显，更大程度上减小摆位误差和肿瘤移动度，提高放疗的精确度。
Abstract:
Abstract: Objective To investigate the effects of different abdominal compression plate positions on setup error and tumor mobility in stereotactic body radiotherapy (SBRT) for liver cancer. Methods Thirty patients pathologically diagnosed with liver cancer were enrolled and divided into abdominal compression group (n=15) and xiphoid process group (n=15) according to their abdominal compression plate positions. A total of 180 groups of 4D-CBCT scanning data were obtained from the 30 patients. The setup errors in each group were recorded and analyzed, and the tumor mobility was analyzed by XVI (X-ray volumetric imaging system) of Elekta linear accelerator. Results The xiphoid process group had smaller setup error in Y direction than abdominal compression group (P<0.05). For tumor mobility in 3 directions, the mean tumor mobility in only Y direction, mean square error of tumor mobility in only Z direction, and maximum tumor mobility in both X and Y directions were all lower in xiphoid process group than abdominal compression group (P<0.05), and the other differences between two groups were trivial (P>0.05). The target margins of xiphoid process group were smaller than those of abdominal pressure group in all 3 directions. Conclusion In liver cancer SBRT, the abdominal compression plate under xiphoid process has more obvious respiratory depression than under abdominal navel, which greatly reduces setup error and tumor mobility, and improves the accuracy in radiotherapy.

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备注/Memo

备注/Memo:
DOI:10.3969/j.issn.1005-202X.2023.09.002
更新日期/Last Update: 2023-09-26