j.issn.1005-202X.2023.09.017]
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普鲁士蓝纳米粒子在生物医学诊疗中的应用()

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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

Title:: Application of Prussian blue nanoparticles in biomedical diagnosis and treatment

Author(s):: GU Yalong; ZHU Jingyu; XIONG Jiabao; ALIFU Nuernisha; School of Medical Engineering and Technology, Xinjiang Medical University, Urumqi 830017, China

摘要:: 普鲁士蓝纳米粒子（PBNPs）由于其尺寸可调、易于合成和表面修饰、具有良好的光热稳定性和生物相容性，近年来引起广泛关注。因其中空介孔的结构和离子交换的特性，PBNPs可作为理想的药物载体和放射性铯或铊中毒的解毒剂；用作MRI和光声成像的对比剂时，可以显著提高图像的成像质量；PBNPs在光热治疗和纳米酶的催化治疗方面也取得令人满意的疗效。本研究对近年来PBNPs在生物医学中成像与治疗方面的应用进行综述，旨在为PBNPs的相关研究提供参考。

Abstract:: Abstract: Prussian blue nanoparticles (PBNPs) have attracted extensive attention in recent years because of their adjustable size, easy synthesis and surface modification, high photothermal stability and biocompatibility. The hollow mesoporous structure and ion exchange characteristics of PBNPs allow it to be used as an ideal drug carrier and an antidote to radioactive cesium or thallium poisoning. Being used as contrast agent in MRI and photoacoustic imaging can significantly improve the image quality. In addition, PBNPs have achieved satisfactory efficacy in photothermal therapy and catalytic therapy of nano enzymes. Herein an overview on the applications of PBNPs in biomedical imaging and treatment in recent years is presented for providing some references for the related research of PBNPs.

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[2]翟明明,杨继庆,李维娜,等.三种纳米Fe_2O_3的制备方法研究[J].中国医学物理学杂志,2013,30(01):3936.[doi:10.3969/j.issn.1005-202X.2013.01.025]

备注/Memo:: 【收稿日期】2023-03-02 【基金项目】国家自然科学基金（62035011）；省部共建中亚高发病成因与防治国家重点实验室开放课题项目（SKL-HIDCA-2022-3）；新疆地区高发疾病研究教育部重点实验室开放课题项目（2023C04）【作者简介】顾亚龙，硕士，讲师，研究方向：生物医学光子学，E-mail:327787388@qq.com 【通信作者】努尔尼沙·阿力甫，博士，副教授，研究方向：生物医学光子学，E-mail: 11530034@zju.edu.com

更新日期/Last Update: 2023-09-26