[1]徐学涛,蒋晓宏,曾利明,等.脑电图联合MRI在新生儿缺氧缺血性脑病诊断及预后的应用[J].中国医学物理学杂志,2022,39(7):856-859.[doi:DOI:10.3969/j.issn.1005-202X.2022.07.011]
　XU Xuetao,JIANG Xiaohong,ZENG Liming,et al.Application of electroencephalography combined with MRI in the diagnosis and prognosis of neonatal hypoxic-ischemic encephalopathy[J].Chinese Journal of Medical Physics,2022,39(7):856-859.[doi:DOI:10.3969/j.issn.1005-202X.2022.07.011]
点击复制

脑电图联合MRI在新生儿缺氧缺血性脑病诊断及预后的应用()
分享到：

《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
39卷
期数:
2022年第7期
页码:
856-859
栏目:
医学影像物理
出版日期:
2022-07-15

文章信息/Info

Title:
Application of electroencephalography combined with MRI in the diagnosis and prognosis of neonatal hypoxic-ischemic encephalopathy
文章编号:
1005-202X（2022）07-0856-04
作者:
徐学涛; 蒋晓宏; 曾利明; 任明会
安徽医科大学附属巢湖医院儿科， 安徽 合肥 238000
Author(s):
XU Xuetao;  JIANG Xiaohong;  ZENG Liming;  REN Minghui
Department of Pediatrics, Chaohu Hospital Affiliated to Anhui Medical University, Hefei 238000, China
关键词:
新生儿; 缺氧缺血性脑病; 脑电图; 磁共振成像
Keywords:
Keywords: neonate hypoxic-ischemic encephalopathy electroencephalography magnetic resonance imaging
分类号:
R725
DOI:
DOI:10.3969/j.issn.1005-202X.2022.07.011
文献标志码:
A
摘要:
目的：分析脑电图（EEG）联合MRI在新生儿缺氧缺血性脑病诊断及预后的应用价值。方法：缺血缺氧性脑病足月患儿和健康足月新生儿各42例，按照是否确诊缺血缺氧性脑病分为观察组和对照组。对两组新生儿进行脑部MRI动脉自旋标记扫描和振幅整合EEG（aEEG）检查，随访6个月，记录并发症和生存情况。结果：（1）观察组患儿aEEG异常比例显著高于对照组（P<0.05）；（2）观察组患儿基底节区和丘脑呈高灌注状态，额叶呈低灌注状态；（3）正常aEEG新生儿中，观察组患儿丘脑核基底节区灌注均值显著高于对照组；（4）aEEG正常和中度异常新生儿中，不良预后患儿丘脑和基底节区灌注显著高于预后良好患儿。结论：EEG联合头颅MRI能够显著提高新生儿缺氧缺血性脑病诊断的敏感性，对不良预后有一定的预测价值。
Abstract:
Abstract: Objective To analyze the application value of electroencephalography (EEG) combined with magnetic resonance imaging (MRI) in the diagnosis and prognosis of neonatal hypoxic-ischemic disease. Methods Forty-two neonates with neonatal hypoxic-ischemic encephalopathy and 42 healthy neonates were divided into observation group and control group according to whether or not hypoxic-ischemic encephalopathy was diagnosed. Two groups of neonates underwent cerebral MRI arterial spin labeling scans and amplitude-integrated EEG (aEEG) examinations, and they were followed-up for 6 months. The complications and survival in the neonates were recorded. Results (1) The proportion of neonates with abnormal aEEG in observation group was significantly higher than that in control group (P<0.05). (2) Neonates in observation group showed hyperperfusion in the basal ganglia and the thalamus, but hypoperfusion in the frontal lobe. (3) Among neonates with normal aEEG, those in observation group had significantly higher mean values of perfusion in the basal ganglia of thalamic nuclei than those in control group. (4) Among neonates with normal and moderately abnormal aEEG, those with poor prognosis has obviously higher perfusion in the thalamus and the basal ganglia than those with favorable prognosis. Conclusion EEG combined with cerebral MRI in neonatal hypoxic-ischemic encephalopathy can significantly improve the sensitivity of diagnosis and has predictive value for poor prognosis.

相似文献/References:

[1]游勇,万静. 思乐扣固定对PICC置管新生儿置管质量和安全性的影响[J].中国医学物理学杂志,2018,35(3):353.[doi:DOI:10.3969/j.issn.1005-202X.2018.03.019]
　YOU Yong,WAN Jing. Statlock fixation for newborns treated with peripherally inserted central catheter and its effects on catheter quality and safety[J].Chinese Journal of Medical Physics,2018,35(7):353.[doi:DOI:10.3969/j.issn.1005-202X.2018.03.019]

备注/Memo

备注/Memo:
【收稿日期】2022-04-21 【基金项目】安徽省重点研究与开发计划项目（202004J07020030） 【作者简介】徐学涛，主治医师，研究方向：新生儿缺氧缺血性脑病，E-mail: 374150176@qq.com 【通信作者】任明会，主治医师，研究方向：儿童重症抢救，E-mail: 532100676@qq.com
更新日期/Last Update: 2022-07-15