[1]李慧君,王琳婧,王锐濠,等.基于Auto-Planning技术的肺癌容积旋转调强放疗计划评估[J].中国医学物理学杂志,2022,39(8):925-928.[doi:DOI:10.3969/j.issn.1005-202X.2022.08.001]
　LI Huijun,WANG Linjing,WANG Ruihao,et al.Evaluation of Auto-Planning technique-based volumetric modulated arc therapy plan for lung cancer[J].Chinese Journal of Medical Physics,2022,39(8):925-928.[doi:DOI:10.3969/j.issn.1005-202X.2022.08.001]
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基于Auto-Planning技术的肺癌容积旋转调强放疗计划评估()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
39卷
期数:
2022年第8期
页码:
925-928
栏目:
医学放射物理
出版日期:
2022-08-04

文章信息/Info

Title:
Evaluation of Auto-Planning technique-based volumetric modulated arc therapy plan for lung cancer
文章编号:
1005-202X（2022）08-0925-04
作者:
李慧君; 王琳婧; 王锐濠; 周露; 彭莹莹; 廖煜良; 张书旭
广州医科大学附属肿瘤医院放疗中心， 广东 广州 510095
Author(s):
LI Huijun;  WANG Linjing;  WANG Ruihao;  ZHOU Lu;  PENG Yingying;  LIAO Yuliang;  ZHANG Shuxu
Radiation Therapy Center, Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou 510095, China
关键词:
Auto-Planning; 肺癌; 容积旋转调强放射治疗; 剂量学
Keywords:
Keywords: Auto-Planning lung cancer volumetric modulated arc therapy dosimetry
分类号:
R734.2；R811.1
DOI:
DOI:10.3969/j.issn.1005-202X.2022.08.001
文献标志码:
A
摘要:
目的：比较基于Auto-Planning技术的自动肺癌容积旋转调强放射治疗（VMAT）计划与物理师手动设计的常规VMAT计划的剂量学差异，研究Auto-Planning技术在肺癌VMAT计划中的优化性能和临床应用价值。方法：随机选取25例已完成全程放疗的肺癌病例，应用Pinnacle3 V9.10计划系统分别进行基于Auto-Planning的自动计划（AP-VMAT）和常规手动计划（M-VMAT）设计，分析比较两组不同计划的肿瘤靶区剂量分布、危及器官受照剂量等剂量学参数。结果：两组计划的靶区覆盖度和危及器官限量均能满足临床要求。AP-VMAT计划靶区最大剂量略高于M-VMAT，但剂量适形度指数明显优于M-VMAT。与M-VMAT计划相比，AP-VMAT有效降低了脊髓受到的最大剂量和平均剂量，双肺的V30、平均剂量以及心脏的V40、V30、平均剂量都在一定程度上有所降低，差异有统计学意义（P<0.05）。结论：对于肺癌VMAT放疗计划，AP-VMAT能够满足临床要求，且比M-VMAT具有更优的靶区适形度，同时可以有效降低脊髓、肺、心脏等危及器官的受照剂量，更好地保护正常组织。
Abstract:
Abstract: Objective To compare the dosimetry differences between the Auto-Planning technique-based volumetric modulated arc therapy (AP-VMAT) plan and the conventional VMAT plan manually designed by the physicist (M-VMAT) for lung cancer, thereby exploring the optimization performance and clinical application value of Auto-Planning technique in VMAT planning for lung cancer. Methods Twenty-five patients with lung cancer who had completed radiotherapy were randomly selected.Two kinds of VMAT plans, namely AP-VMAT plan and M-VMAT plan, were designed for each patient. AP-VMAT plans were automatically generated by Pinnacle3 V9.10 system, while M-VMAT plans were manually designed. The dose distribution of the target area and organs-at-risk sparing were analyzed and compared between two groups of plans. Results The dose coverage of the target area and limit of organs-at-risk met the clinical requirements in both groups. The maximum dose to the target area in AP-VMAT plan was slightly higher than that in M-VMAT plan, but the conformity index in AP-VMAT plan was significantly better. Compared with M-VMAT plan, AP-VMAT plan effectively reduced the maximum dose and mean dose received by spinal cord, decreased the V30 and mean dose in both lungs and the V40, V30 and mean dose in heart, and the differences were statistically significant (P<0.05). Conclusion AP-VMAT plan meets the clinical requirements for lung cancer.Compared with M-VMAT plan, AP-VMAT plan has better target dose distribution and reduces the doses to spinal cord, lungs and heart, protecting normal tissues better.

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备注/Memo

备注/Memo:
【收稿日期】2022-02-18 【基金项目】广东省医学科研基金（A2021283）；广州市卫生健康科技一般引导项目（20201A011097, 20201A010062） 【作者简介】李慧君，硕士研究生，研究方向：肿瘤放射物理学、医学图像重建，E-mail: jun.jie.kun@163.com 【通信作者】张书旭，博士，教授，主任技师，博士生导师，E-mail: gthzsx@163.com
更新日期/Last Update: 2022-09-05