[1]石环环,曹禺,周亚诺,等.微流控浓度梯度芯片的开发与生物化学应用研究[J].中国医学物理学杂志,2021,38(10):1299-1303.[doi:DOI:10.3969/j.issn.1005-202X.2021.10.021]
 SHI Huanhuan,CAO Yu,et al.Development of microfluidic concentration gradient chip and its application in biochemistry[J].Chinese Journal of Medical Physics,2021,38(10):1299-1303.[doi:DOI:10.3969/j.issn.1005-202X.2021.10.021]
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微流控浓度梯度芯片的开发与生物化学应用研究()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
38卷
期数:
2021年第10期
页码:
1299-1303
栏目:
医学生物物理
出版日期:
2021-10-27

文章信息/Info

Title:
Development of microfluidic concentration gradient chip and its application in biochemistry
文章编号:
1005-202X(2021)10-1299-05
作者:
石环环12曹禺1周亚诺12万亚茹12赵亚丽3
1.南昌航空大学教育部无损检测重点实验室, 江西 南昌 330000; 2.南昌航空大学测试与光电工程学院生物医学工程系, 江西 南昌 330000; 3.长沙市第四医院/湖南师范大学附属长沙医院, 湖南 长沙 410083
Author(s):
SHI Huanhuan1 2 CAO Yu1 ZHOU Yanuo1 2 WAN Yaru1 2 ZHAO Yali3
1. Key Laboratory of Nondestructive Testing, Ministry of Education, Nanchang Hangkong University, Nanchang 330000, China 2. Department of Biomedical Engineering, School of Testing and Optoelectronic Engineering, Nanchang Hangkong University, Nanchang 330000, China 3. Changsha Hospital of Hunan Normal University/the Forth Hospital of Changsha, Changsha 410083
关键词:
微流控浓度梯度芯片药物筛选毒性分析材料合成综述
Keywords:
Keywords: microfluidic concentration gradient chip drug screening toxicity analysis chemotaxis materials synthesis review
分类号:
R318;R34
DOI:
DOI:10.3969/j.issn.1005-202X.2021.10.021
文献标志码:
A
摘要:
在生物化学分析中系统研究样本与不同浓度组分间的相互作用是至关重要的。微流控芯片技术能够在微米级的通道内完成精确的液体控制,近年来被普遍应用于生物化学分析领域。微流控浓度梯度芯片是一种能够快速构建稳定生物化学浓度梯度的工具,能够与大多数细胞培养、化学分析等技术相结合,为传统的生化分析提供新平台。本文综述微流控浓度梯度芯片的形成机制及其在生物化学等领域的应用,为拓宽浓度梯度相关应用研究提供新思路。
Abstract:
Abstract: It is important to systematically study the interactions between samples and different concentrations of components in biochemical analysis. Microfluidic chip technology has been widely used in biochemical analysis in recent years, because it can realize accurate liquid control in micron-sized channel. Microfluidic concentration gradient chip is a tool that can rapidly construct stable biochemical concentration gradient and can be combined with most cell culture, chemical analysis and other techniques, offering a new platform for traditional biochemical analysis. Herein the formation mechanism of microfluidic concentration gradient chip and its application in biochemistry and other fields are reviewed, thereby providing a new idea for broadening the application research related to concentration gradient.

备注/Memo

备注/Memo:
【收稿日期】2020-12-05 【基金项目】江西省自然科学基金(20202BABL212003);江西省教育厅科技项目(GJJ190510);南昌航空大学博士启动基金项目(EA202008205);国家自然科学基金(62101231);湖南省自然科学基金(2021JJ40618) 【作者简介】石环环,博士,讲师,研究方向:生物医学传感器与智能仪器,E-mail: shihuanhuancsu@126.com 【通信作者】赵亚丽,硕士,中级工程师,研究方向:生理建模与仿真,E-mail: zhaoyali-789@163.com
更新日期/Last Update: 2021-10-29