[1]时飞跃,秦伟,陈飞,等.呼吸时相和模体位置对4D-CT图像均匀性的影响[J].中国医学物理学杂志,2020,37(1):65-68.[doi:DOI:10.3969/j.issn.1005-202X.2020.01.013]
　SHI Feiyue,QIN Wei,et al.Effects of respiratory phase and phantom position on uniformity of 4D-CT image[J].Chinese Journal of Medical Physics,2020,37(1):65-68.[doi:DOI:10.3969/j.issn.1005-202X.2020.01.013]
点击复制

呼吸时相和模体位置对4D-CT图像均匀性的影响()
分享到：

《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
37
期数:
2020年第1期
页码:
65-68
栏目:
医学影像物理
出版日期:
2020-01-25

文章信息/Info

Title:
Effects of respiratory phase and phantom position on uniformity of 4D-CT image
文章编号:
1005-202X（2020）01-0065-04
作者:
时飞跃1; 2; 秦伟1; 陈飞1; 赵环宇1; 金洵3
1.南京医科大学附属南京医院（南京市第一医院）肿瘤放疗中心， 江苏 南京 210006；2.南京医科大学医学物理研究中心， 江苏 南京 210029； 3.南京中医药大学第二临床医学院， 江苏 南京 210023
Author(s):
SHI Feiyue1;  2;  QIN Wei1;  CHEN Fei1;  ZHAO Huanyu1;  JIN Xun3
1. Radiation Therapy Center, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China; 2. Center of Medical Physics, Nanjing Medical University, Nanjing 210029, China; 3. the Second Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing 210023, China
关键词:
四维CT; 图像均匀性; 呼吸时相; 模体位置
Keywords:
Keywords: four-dimensional computed tomography;  image uniformity;  respiratory phase;  phantom position
分类号:
R811.1；R318
DOI:
DOI:10.3969/j.issn.1005-202X.2020.01.013
文献标志码:
A
摘要:
目的：通过分析Catphan模体CTP486模块的四维CT（4D-CT）图像，研究呼吸时相和模体位置对4D-CT图像均匀性的影响。方法：使用西门子Sensation Open CT模拟机和瓦里安RPM系统，获取Catphan 504模体CTP486模块的4D-CT图像。对3种模体位置情形进行研究。情形A：模体悬空放置；情形T：模体下有一个碳纤维CT平板床；情形B+T：模体下有一个碳纤维固定底板和一个CT平板床。每种情形重复3次测量。使用DoseLab放疗验证软件分析4D-CT图像，得到图像均匀性值（U）。对每一套4D-CT重建10个呼吸时相（0%, 10%,[ ?], 90%）的CT图像序列。对U值进行统计分析和比较研究。结果：4D-CT所有CT序列的U值均小于5 HU。每种情形得到30个U值数据，情形A、情形T和情形B+T 3种情形U值分别为（1.44±0.79）、（1.91±0.91）和（1.99±0.77） HU。统计U值对应的4个边缘感兴趣区（ROI）出现的次数和比例，情形T中ROI 22（9点钟方向）出现13次（占比43.33%），情形B+T中ROI 23（12点钟方向）出现13次（占比43.33%）。结论：本研究中4D-CT的图像均匀性满足使用要求，不同呼吸时相4D-CT的图像均匀性值不同，模体摆放位置对4D-CT的图像均匀性有一定影响，碳纤维CT平板床和固定底板的存在使4D-CT 的图像均匀性变差。
Abstract:
Abstract: Objective To investigate the effects of respiratory phase and phantom position on the uniformity of four-dimensional computed tomography (4D-CT) images by analyzing the 4D-CT image of the CTP486 module in Catphan phantom. Methods Siemens Sensation Open CT simulator and Varian RPM system were used to obtain the 4D-CT images of CTP486 module in Catphan 504 phantom. The following 3 cases in which the phantom position was different were utilized to carry out this study. In Case A, the Catphan phantom was hung in the air; in Case T, a carbon fiber CT flat table was placed under the phantom; and in Case B+T, a carbon fiber immobilization baseplate and the CT flat table were placed under the phantom. Three measurements were implemented for each case. DoseLab radiotherapy verification software was used to analyze the 4D-CT images, and the image uniformity (U values) were obtained. Ten series of CT were reconstructed for 10 respiratory phases (0%, 10%,[ ?], 90%) for each 4D-CT measurement. Statistical analysis and comparative study were conducted on U values. Results All the U values of 4D-CT were smaller than 5 HU. For each case, 30 U values were obtained. The U values in Case A, Case T and Case B+T were (1.44±0.79), (1.91±0.91) and (1.99±0.77) HU, respectively. The numbers of times and proportions of the occurrence of 4 peripheral regions of interest which were corresponding to U values were analyzed. There were 13 ROI 22 (9 o’clock position) in case T, with a proportion of 43.33%, and 13 ROI 23 (12 o’clock position) in Case B+T, with a proportion of 43.33%. Conclusion The uniformity of 4D-CT images meets the requirements. The uniformity values of 4D-CT images for different respiratory phases are different. The phantom position has certain effects on the uniformity of 4D-CT images, and the existence of carbon fiber CT flat table and immobilization baseplate reduces the uniformity of 4D-CT images.

相似文献/References:

[1]柏晗,等.基于四维CT下胸部肿瘤调强计划中心脏和食道的剂量评估[J].中国医学物理学杂志,2016,33(3):293.[doi:DOI:10.3969/j.issn.1005-202X.2016.03.015]
　[J].Chinese Journal of Medical Physics,2016,33(1):293.[doi:DOI:10.3969/j.issn.1005-202X.2016.03.015]
[2]李毅,唐丰文,张晓智. 基于四维CT和锥形束CT确定非小细胞肺癌放疗靶区外放边界[J].中国医学物理学杂志,2016,33(9):892.[doi:10.3969/j.issn.1005-202X.2016.09.005]
　[J].Chinese Journal of Medical Physics,2016,33(1):892.[doi:10.3969/j.issn.1005-202X.2016.09.005]
[3]周丁屹,蒋大振,全红,等. 四维CT扫描参数和扫描模式对CT值的影响[J].中国医学物理学杂志,2016,33(9):919.[doi:10.3969/j.issn.1005-202X.2016.09.010]
　[J].Chinese Journal of Medical Physics,2016,33(1):919.[doi:10.3969/j.issn.1005-202X.2016.09.010]
[4]高文超,王军良,周振山,等. 基于四维CT和TumorLoc软件测定肺下叶呼吸动度[J].中国医学物理学杂志,2016,33(9):944.[doi:10.3969/j.issn.1005-202X.2016.09.015]
　[J].Chinese Journal of Medical Physics,2016,33(1):944.[doi:10.3969/j.issn.1005-202X.2016.09.015]
[5]时飞跃,柏正璐,秦航,等.西门子CT模拟机图像均匀性的长期稳定性分析[J].中国医学物理学杂志,2018,35(9):1035.[doi:10.3969/j.issn.1005-202X.2018.09.008]
　SHI Feiyue,BAI Zhenglu,QIN Hang,et al.Long-term stability of image uniformity for a SIEMENS CT simulator[J].Chinese Journal of Medical Physics,2018,35(1):1035.[doi:10.3969/j.issn.1005-202X.2018.09.008]
[6]吴文婧,李毅,孙玄子,等.基于4DCT和形变配准技术评估呼吸运动对肺癌立体定向放射治疗过程中剂量的影响[J].中国医学物理学杂志,2019,36(12):1406.[doi:DOI:10.3969/j.issn.1005-202X.2019.12.008]
　WU Wenjing,LI Yi,SUN Xuanzi,et al.Dose variation caused by respiratory motion on SBRT for lung tumors: an analysis based on 4DCT and deformable registration[J].Chinese Journal of Medical Physics,2019,36(1):1406.[doi:DOI:10.3969/j.issn.1005-202X.2019.12.008]

备注/Memo

备注/Memo:
【收稿日期】2019-07-19 【基金项目】国家自然科学基金青年科学基金（81603674）；江苏省自然科学基金青年基金（BK20161049） 【作者简介】时飞跃，研究方向：肿瘤放射物理，E-mail: shifeiyue2013@126.com 【通信作者】赵环宇，副主任医师，研究方向：肿瘤放射治疗，E-mail: oncodoc@sina.com
更新日期/Last Update: 2020-01-14