早孕期三维能量多普勒超声对胎儿生长受限的预测价值分析-《中国医学物理学杂志》

文章信息/Info

Title:: Prediction of fetal growth restriction in first trimester by three-dimensional power Doppler ultrasoud

Author(s):: WANG Yunfang; YANG Fang; CHEN Cuihua; QIU Yuwen; LU Qianwen; XU Cailing; TAO Zixin; Department of Obstetrics and Gynecology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China

Keywords:: three-dimensional power Doppler ultrasound; fetal growth restriction; vascularization index; flow index; vascularization-blood flow index; placenta quotient; placenta volume

摘要:: 目的：探讨三维能量多普勒超声指标对胎儿生长受限（FGR）的预测价值。方法：前瞻性连续收集2016年12月~2017年12月在南方医科大学南方医院进行产前早孕NT检查的正常单胎妊娠孕妇231例作为研究对象，并采集早孕期胎盘三维能量多普勒容积数据存至硬盘，对所有孕妇进行随访至出生后，根据随访诊断结果分为FGR组（n=11例）和正常组（n=220例）。利用GE 4DView软件进行离线测量胎盘体积并得出胎盘血管指数（包括胎盘血管化指数、血流指数、血管化-血流指数）。结果：FGR组胎盘血管化指数、血管化-血流指数均显著低于正常组（P<0.05），差异有统计学意义（P<0.05）。结论：早孕期胎盘三维能量多普勒超声指标对于FGR的早期预测有重要价值意义，为早期预测FGR提供量化指标，值得推广应用。

Abstract:: Objective To investigate the value of three-dimensional power Doppler ultrasound for the prediction of fetal growth restriction (FGR). Methods A total of 231 pregnant women with normal singleton pregnancy who underwent NT examination of prenatal early pregnancy in Nanfang Hospital of Southern Medical University from December 2016 to December 2017 were prospectively selected as subjects. The volume data obtained by three-dimensional power Doppler of placenta in early pregnancy were saved to the hard disk, and all pregnant women were followed up until their babies were born. According to the follow-up results, they were divided into FGR group (n=11) and normal group (n=220). GE 4DView software was used for the off-line measurement of placenta volumes and placental vascular indexes, including placental vascularization index, blood flow index and vascularization-blood flow index. Results The placental vascularization index, vascularization-blood flow index in FGR group were significantly lower than those in normal group, with statistical differences (P<0.05). Conclusion Three-dimensional power Doppler ultrasound of placenta in early pregnancy, which provides a quantitative index for the early prediction of FGR, is of great significance and is worthy of popularization and application.