[1]张昊兆,杨雪倩,王丹利,等. 基于核磁共振CPMG方法比较3D打印体模材料的吸水性[J].中国医学物理学杂志,2018,35(7):833-838.[doi:DOI:10.3969/j.issn.1005-202X.2018.07.018]
　ZHANG Haozhao,YANG Xueqian,WANG Danli,et al. Comparison of water absorbability of 3D printed phantom materials based on MR CPMG method[J].Chinese Journal of Medical Physics,2018,35(7):833-838.[doi:DOI:10.3969/j.issn.1005-202X.2018.07.018]
点击复制

 基于核磁共振CPMG方法比较3D打印体模材料的吸水性()
分享到：

《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
35卷
期数:
2018年第7期
页码:
833-838
栏目:
生物材料与力学
出版日期:
2018-07-20

文章信息/Info

Title:
 Comparison of water absorbability of 3D printed phantom materials based on MR CPMG method
文章编号:
1005-202X（2018）07-0833-06
作者:
 张昊兆1; 杨雪倩1; 王丹利2; 邱建峰1
 1.泰山医学院医学工程技术研究中心， 山东 泰安 271016； 2.苏州纽迈分析仪器股份有限公司， 江苏 苏州 215163
Author(s):
 ZHANG Haozhao1;  YANG Xueqian1;  WANG Danli2;  QIU Jianfeng1
 1. Medical Engineering and Technology Research Center, Taishan Medical Univerisiry, Tai’an 271016, China; 2. Suzhou Niumag Corporation, Suzhou 215163, China
关键词:
 ; 孔隙度; 磁共振体模; 吸水性; 聚甲基丙烯酸甲酯; 3D打印材料; CPMG
Keywords:
 ; Keywords: porosity;  magnetic resonance phantom;  water absorbability;  polymethylmethacrylate;  three-dimensional printed material;  Carr Purcell Meiboom Gill
分类号:
R-331；O482.53
DOI:
DOI:10.3969/j.issn.1005-202X.2018.07.018
文献标志码:
A
摘要:
 核磁共振体模是用于磁共振成像（MRI）测试的重要组件，由MRI中表现为无信号的聚甲基丙烯酸甲酯（PMMA）材料外壳内装PMMA材料制作的测试组件以及体模测试液（纯水、硫酸铜和氯化钠）组成。近年来，越来越多的磁共振体模通过3D打印的方式制作，来满足体模个性化设计和快速成型需求，然而对于3D打印制作的体模是否能像PMMA材料那样有效防水这一问题尚无相关研究，本研究基于核磁共振PQ001核磁共振分析仪，利用CPMG（Carr Purcell Meiboom Gill）硬脉冲序列测试6种材料（包括3D打印材料：ABS树脂、SLA光敏树脂和DLP光敏树脂；常用体模制备材料：硅胶、水凝胶和PMMA）饱水前后的[T2]弛豫时间，以此比较6种不同性质材料的孔隙大小。同时结合6种材料饱水前后[T2]信号量的变化率，综合比较材料的吸水情况。结果表明PMMA和光敏树脂、ABS等3D打印材料的孔隙大小明显低于常规体模材料硅胶和水凝胶，而在吸水性上3D打印材料ABS和SLA光敏树脂接近PMMA材料。综合孔隙大小和吸水性两方面比较，ABS和SLA光敏树脂材料在防水防渗透方面与常规磁共振体模外壳材料PMMA相近，可以有效替代PMMA材料用于磁共振体模外壳和插件。
Abstract:
 Abstract: Magnetic resonance (MR) phantom, an important component for MR imaging test, was composed of polymethylmethacrylate (PMMA) material shell, PMMA material test components and test solution (pure water, copper sulfate and sodium chloride). In recent years, more and more MR phantoms were produced by three-dimensional (3D) printing technique in order to meet the requirements for phantom personalized design and rapid prototyping. However, there was no relevant research on whether 3D printed phantom could be effectively waterproof like PMMA materials. Six kinds of materials were investigated in this study, including 3 kinds of 3D printed materials (ABS resin, SLA photosensitive resin and DLP photosensitive resin) and 3 kinds of commonly used phantom materials (silica gel, hydrogels and PMMA). Based on PQ001 MR analyzer, we used CPMG (Carr Purcell Meiboom Gill) hard pulse sequence to test the [T2] relaxation time of 6 kinds of materials before and after saturation for comparing their pore sizes. Meanwhile, the water absorbability of different materials was comprehensively compared with the consideration of [T2] relaxation time and the change rate of [T2] semaphore before and after saturation. The results revealed that the pore size of PMMA, photosensitive resin, ABS and other 3D printed materials were significantly lower than that of silica and hydrogel, but the water absorbability of ABS and SLA photosensitive resin were similar to PMMA. Considering both pore size and water absorbability, ABS and SLA photosensitive resin materials which have a similar performance with PMMA of conventional MR phantom shell material in waterproof and anti-seepage could be an effective alternative to PMMA for phantoms and inserts.

相似文献/References:

[1]王遥,霍万里,熊壮,等.TACE手术中不同站姿下铅眼镜和铅面罩对医生眼晶状体防护效果的蒙特卡洛模拟比较[J].中国医学物理学杂志,2016,33(6):553.[doi:DOI:10.3969/j.issn.1005-202X.2016.06.003]
　[J].Chinese Journal of Medical Physics,2016,33(7):553.[doi:DOI:10.3969/j.issn.1005-202X.2016.06.003]
[2]张新,谷晓芳,王培臣,等.轻离子束治疗设备注册检验关键技术问题[J].中国医学物理学杂志,2016,33(6):559.[doi:10.3969/j.issn.1005-202X.2016.06.004]
　[J].Chinese Journal of Medical Physics,2016,33(7):559.[doi:10.3969/j.issn.1005-202X.2016.06.004]
[3]江芬芬,王培,康盛伟,等. 热释光剂量片测量肺部肿瘤放疗剂量的方法[J].中国医学物理学杂志,2016,33(6):564.[doi:10.3969/j.issn.1005-202X.2016.06.005]
　[J].Chinese Journal of Medical Physics,2016,33(7):564.[doi:10.3969/j.issn.1005-202X.2016.06.005]
[4]刘洪源,彭威,杨锐,等. 锥形束CT离线校正肺癌摆位误差[J].中国医学物理学杂志,2016,33(6):573.[doi:10.3969/j.issn.1005-202X.2016.06.007]
　[J].Chinese Journal of Medical Physics,2016,33(7):573.[doi:10.3969/j.issn.1005-202X.2016.06.007]
[5]赵彪,潘香,杨毅,等. 右乳癌保乳术后瘤床同步X线和后程电子线补量调强放疗剂量学比较[J].中国医学物理学杂志,2016,33(6):576.[doi:10.3969/j.issn.1005-202X.2016.06.008]
　[J].Chinese Journal of Medical Physics,2016,33(7):576.[doi:10.3969/j.issn.1005-202X.2016.06.008]
[6]邓南,钱建庭,刁现芬,等. 基于宽带检测放疗X-光光声效应仿体实验[J].中国医学物理学杂志,2016,33(9):865.[doi:DOI:10.3969/j.issn.1005-202X.2016.09.001]
　[J].Chinese Journal of Medical Physics,2016,33(7):865.[doi:DOI:10.3969/j.issn.1005-202X.2016.09.001]
[7]张先稳,李军,张西志,等. 宫颈癌术后5野调强放疗4个变量组合的最佳治疗模式的剂量学[J].中国医学物理学杂志,2016,33(9):872.[doi:10.3969/j.issn.1005-202X.2016.09.002]
　[J].Chinese Journal of Medical Physics,2016,33(7):872.[doi:10.3969/j.issn.1005-202X.2016.09.002]
[8]胡健,李承军,徐利明,等. 床面倾斜对剂量验证通过率的影响[J].中国医学物理学杂志,2016,33(9):881.[doi:10.3969/j.issn.1005-202X.2016.09.003]
　[J].Chinese Journal of Medical Physics,2016,33(7):881.[doi:10.3969/j.issn.1005-202X.2016.09.003]
[9]陈亚正,肖明勇,孙春堂,等. 准直器角度对宫颈癌术后VMAT计划的影响[J].中国医学物理学杂志,2016,33(9):885.[doi:10.3969/j.issn.1005-202X.2016.09.004]
　[J].Chinese Journal of Medical Physics,2016,33(7):885.[doi:10.3969/j.issn.1005-202X.2016.09.004]
[10]李毅,唐丰文,张晓智. 基于四维CT和锥形束CT确定非小细胞肺癌放疗靶区外放边界[J].中国医学物理学杂志,2016,33(9):892.[doi:10.3969/j.issn.1005-202X.2016.09.005]
　[J].Chinese Journal of Medical Physics,2016,33(7):892.[doi:10.3969/j.issn.1005-202X.2016.09.005]

备注/Memo

备注/Memo:
 【收稿日期】2018-01-22
【基金项目】国家重点研发计划（2016YFC0103400）
【作者简介】张昊兆，研究方向：医学成像，E-mail: haozhao111@foxmail.com
【通信作者】邱建峰，博士，教授，研究方向：医学成像，E-mail: jfqiu100@163.com
更新日期/Last Update: 2018-07-24