[1]蔡爱楠,随力,王君. CT/MRI双模态造影剂的制备及研究进展[J].中国医学物理学杂志,2018,35(2):219-223.[doi:DOI:10.3969/j.issn.1005-202X.2018.02.020]
 CAI Ainan,SUI Li,WANG Jun. Preparation and research progress of CT/MRI bimodal contrast agent[J].Chinese Journal of Medical Physics,2018,35(2):219-223.[doi:DOI:10.3969/j.issn.1005-202X.2018.02.020]
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 CT/MRI双模态造影剂的制备及研究进展()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
35卷
期数:
2018年第2期
页码:
219-223
栏目:
生物材料与力学
出版日期:
2018-02-08

文章信息/Info

Title:
 Preparation and research progress of CT/MRI bimodal contrast agent
文章编号:
1005-202X(2018)02-0219-05
作者:
 蔡爱楠随力王君
 上海理工大学医疗器械与食品学院, 上海 200093
Author(s):
 CAI Ainan SUI Li WANG Jun
 School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China
关键词:
 电子计算机断层扫描核磁共振成像双模态造影剂综述
Keywords:
 Keywords: computed tomography nuclear magnetic resonance imaging bimodal contrast agent review
分类号:
R331
DOI:
DOI:10.3969/j.issn.1005-202X.2018.02.020
文献标志码:
A
摘要:
 电子计算机断层扫描(CT)用途广泛,常用于解剖学成像,骨成像和肿瘤成像等,但软组织对比度较低。核磁共振成像(MRI)的软组织对比度高,但成像时间长,价格昂贵。将CT成像技术与MRI技术合二为一使其优势互补,可以在短时间内得到更准确的生物信息。如今CT/MRI双模态造影剂相关的综述文献并不是很多。本文在CT/MRI双模态分子影像前驱物的基础上归纳一些制备CT/MRI双模态造影剂的方法,如纳米乳法,表面物理修饰法,表面化学修饰法,氯胺-T碘标记法,氧化还原法,并展望了未来CT/MRI双模态造影剂的发展。
Abstract:
 Though computed tomography (CT) is widely used in anatomical imaging, bone imaging, tumor imaging and so on, CT had a low soft-tissue contrast. However, magnetic resonance imaging (MRI) has a high soft-tissue contrast, with a long imaging time and expensive cost. Therefore, CT and MRI can be combined to make complementary advantages for obtaining more accurate biological information in a short time. Nowadays, the relevant review on CT/ MRI bimodal contrast agent is few. Herein we summarized several methods to prepare CT/MRI bimodal contrast agent based on some predecessors of CT/MRI bimodal contrast agent, such as nanoemulsion method, surface physical modification method, surface chemical modification method, chloramine-T iodine labeling method, and oxidation reduction method. Finally, the developments of CT/MRI bimodal contrast agent are prospected.

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备注/Memo

备注/Memo:
 【收稿日期】2017-11-02
【基金项目】国家自然科学基金(11179015, 51173108);上海理工大学科技发展项目(16KJFZ107, 2017KJFZ160)
【作者简介】蔡爱楠,硕士研究生,研究方向:生物医学影像,E-mail: caiainan@163.com
【通信作者】随力,教授,研究方向:神经工程,E-mail: lsui@usst.edu.cn
更新日期/Last Update: 2018-01-29