[1]姚雷,夏兵,曾程,等. 不同计划系统胸部肿瘤物理剂量参数比较与分析[J].中国医学物理学杂志,2018,35(5):526-531.[doi:DOI:10.3969/j.issn.1005-202X.2018.05.006]
　YAO Lei,XIA Bing,ZENG Cheng,et al. Comparison and analysis of physical dose parameters between two different planning systems for radiotherapy in thoracic cancer[J].Chinese Journal of Medical Physics,2018,35(5):526-531.[doi:DOI:10.3969/j.issn.1005-202X.2018.05.006]
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 不同计划系统胸部肿瘤物理剂量参数比较与分析()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
35卷
期数:
2018年第5期
页码:
526-531
栏目:
医学放射物理
出版日期:
2018-05-22

文章信息/Info

Title:
 Comparison and analysis of physical dose parameters between two different planning systems for radiotherapy in thoracic cancer
文章编号:
1005-202X（2018）05-0526-06
作者:
 姚雷1; 夏兵1; 曾程2; 张硕1; 纪天龙1; 易海云1; 孙路1
 1.中国医科大学附属第一医院放疗科， 辽宁 沈阳 110001； 2.沈阳市第五人民医院放疗科， 辽宁 沈阳 110001
Author(s):
 YAO Lei1;  XIA Bing1;  ZENG Cheng2;  ZHANG Shuo1;  JI Tianlong1;  YI Haiyun1;  SUN Lu1
 1. Department of Radiation Oncology, the First Affiliated Hospital of China Medical University, Shenyang 110001, China;
2. Department of Radiation Oncology, Shenyang Fifth People Hospital, Shenyang 110001, China
关键词:
 ; 胸部肿瘤; 静态调强放疗; 剂量体积直方图; Oncentra计划系统; Raystation计划系统
Keywords:
 ; thoracic cancer;  intensity-modulated radiotherapy;  dose-volume histogram;  Oncentra planning system;  Raystation planning system
分类号:
R730.55
DOI:
DOI:10.3969/j.issn.1005-202X.2018.05.006
文献标志码:
A
摘要:
 目的：探讨不同计划系统胸部肿瘤患者的静态调强放疗计划的物理剂量参数，比较两种计划系统Oncentra和Raystation的剂量体积直方图，为临床治疗更优选择提供依据。 方法：回顾129例胸部肿瘤患者静态调强治疗计划，比较和分析两个计划系统Oncentra4.3和Raystation 4.72在同一加速器（医科达Synergy）相同射野、子野和子野MU、相同计算网格条件下的靶区（D98、D95、D50、D2）、脊髓（D2）、全肺（V5、V20）、肺平均剂量的物理参数。 结果：同一治疗计划（包括RT image、RT plan、RT structure）经过两个不同计划系统计算（保持相同的计算网格），剂量体积直方图有一定差异。Lung_V5、Lung_V20、Lung_Dmean误差较大，Cord_D2、PTV_D98、PTV_D95、PTV_D50、PTV_D2误差较小。除Lung_V5外，其他差异均符合正态分布，这个差异具有统计学意义。 结论：不同的计划系统之间存在着一定的差异，在评估不同计划系统的计划时，要考虑计划系统之间因建模及算法等原因所造成的剂量分布差异，尤其是在考虑胸部肿瘤患者肺受量，应针对具体病例及计划系统进行分析。
Abstract:
 Objective To investigate the differences of the physical dose evaluation in different intensity-modulated radiotherapy (IMRT) plans and compare the dose-volume histogram (DVH) parameters between Oncentra and Raystation planning systems for providing a basis for selecting a better treatment option. Methods A retrospective analysis was performed on the clinical data of 129 thoracic tumor patients. With the same field, segment, monitor units and computational grid in the same accelerator (Elekta Synergy), the D98, D95, D50 and D2 of target areas, the D2 of spinal cord and the V5, V20, mean dose of lung were calculated with Oncentra 4.3 and Raystation 4.72 planning systems. Results The same treatment plan, including RT image, RT plan and RT structure, was calculated by two different planning systems (keeping the same computational grid), and the results revealed some differences in the DVH. The differences were relatively larger in Lung_V5, Lung_V20, Lung_Dmean, and relatively smaller in Cord_D2 and PTV_D98, PTV_D95, PTV_D50, PTV_D2. Except for Lung_V5, the other differences were in the normal distribution, with statistical significance. Conclusion Due to the differences between different planning systems, the differences in dose distributions between the different planning systems which were caused by modeling and algorithms should be attentive, especially the whole lung dose in thoracic tumor patients which should be analyzed based on the comprehensive consideration of the condition of specific case and the selection of planning system.

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备注/Memo

备注/Memo:
 【收稿日期】2017-11-18
【作者简介】姚雷，放射物理师，助理研究员，研究方向：放射物理、放射治疗计划设计及验证、加速器质控及剂量学QA，E-mail: summer_yaolei@sina.com
【通信作者】夏兵，放射物理师，副研究员，研究方向：放射物理、放射治疗计划建模及验证、加速器质控及剂量学QA，E-mail:xia6581@sohu.com
更新日期/Last Update: 2018-05-22