[1]雷海红,陈善凤,叶铭兰,等.3D打印皮肤补偿膜在乳腺癌调强放疗计划的剂量学研究[J].中国医学物理学杂志,2025,42(12):1564-1568.[doi:DOI:10.3969/j.issn.1005-202X.2025.12.004]
　LEI Haihong,CHEN Shanfeng,YE Minglan,et al.Dosimetric study of 3D-printed skin compensators in intensity-modulated radiotherapy for breast cancer[J].Chinese Journal of Medical Physics,2025,42(12):1564-1568.[doi:DOI:10.3969/j.issn.1005-202X.2025.12.004]
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3D打印皮肤补偿膜在乳腺癌调强放疗计划的剂量学研究()

《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
42
期数:
2025年第12期
页码:
1564-1568
栏目:
医学放射物理
出版日期:
2025-12-29

文章信息/Info

Title:
Dosimetric study of 3D-printed skin compensators in intensity-modulated radiotherapy for breast cancer
文章编号:
1005-202X（2025）12-1564-05
作者:
雷海红1; 陈善凤2; 叶铭兰2; 肖凤峰1
1.珠海市人民医院放疗科， 广东 珠海 519000； 2.肇庆市第二人民医院放疗物理技术科， 广东 肇庆 526300
Author(s):
LEI Haihong1;  CHEN Shanfeng2;  YE Minglan2;  XIAO Fengfeng1
1. Department of Radiotherapy, Zhuhai Peoples Hospital, Zhuhai 519000, China 2. Department of Radiotherapy Physics and Technology, the Second Peoples Hospital of Zhaoqing, Zhaoqing 526300, China
关键词:
乳腺癌; 3D打印; 补偿膜; 放射治疗; 剂量学
Keywords:
Keywords: breast cancer 3D-printed compensator radiation therapy dosimetry
分类号:
R318；R811.1
DOI:
DOI:10.3969/j.issn.1005-202X.2025.12.004
文献标志码:
A
摘要:
目的：探讨3D打印皮肤补偿膜在乳腺癌术后辅助放疗方面的剂量学影响。方法：使用两种补偿膜设计调强放疗计划，常规补偿膜组采用常规补偿膜，3D补偿膜组采用3D打印皮肤补偿膜，比较两组计划剂量学参数差异。结果：3D补偿膜组的皮肤空隙显著小于常规补偿膜组（P<0.05）。3D补偿膜组的覆盖率（CR）和均匀性指数（HI）为（93.00±0.04）%和0.11±0.02，常规补偿膜组的CR和HI为（91.00±0.03）%和0.12±0.02，两组比较差异均有统计学意义（P<0.05）。3D补偿膜组肺受量（V10、V20、V30）及心脏受量（V30、V40）分别为34.21%、18.25%、13.36%和19.93%、10.63%，常规补偿膜组肺受量（V10、V20、V30）及心脏受量（V30、V40）分别为35.09%、18.52%、13.66%和20.53%、10.94%，3D补偿膜组优于常规补偿膜组（P<0.05）。结论：3D补偿膜个体化程度高，有效改善靶区剂量均匀分布，具有比常规补偿膜更好的适形性和贴合性，适合临床应用。
Abstract:
Abstract: Objective To explore the dosimetric effect of 3D-printed skin compensators on postoperative adjuvant radiotherapy for breast cancer. Methods Intensity-modulated radiotherapy plans were designed using two kinds of compensators: the conventional compensator group was treated with standard compensator, while the 3D compensator group adopted 3D-printed compensator. Dosimetric differences between the two groups were compared. Results The skin void volume in the 3D compensator group were significantly smaller than that in the conventional compensator group (P<0.05). For the 3D compensator group versus the conventional compensator group, the coverage rate was (93.00±0.04)% versus (91.00±0.03)%, and the homogeneity index was 0.11±0.02 versus 0.12±0.02, with statistically significant differences observed (P<0.05). The lung dose parameters (V10, V20, V30) and heart dose parameters (V30, V40) in the 3D compensator group were 34.21%, 18.25%, 13.36%, 19.93%, and 10.63%, respectively, and the corresponding values in the conventional compensator group were 35.09%, 18.52%, 13.66%, 20.53%, and 10.94%, respectively. The 3D compensator group had superior dosimetric outcomes as compared with the conventional compensator group (P<0.05). Conclusion Highly-personalized 3D-printed compensators can effectively improve the target dose uniformity, and exhibit better conformability and fit than conventional compensator, making them well-suited for clinical application.

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备注/Memo

备注/Memo:
【收稿日期】2025-07-08 【基金项目】广东省重点实验室基金（2021B1212040004） 【作者简介】雷海红，副主任技师，研究方向：肿瘤放射治疗物理与技术，E-mail: 547464007@qq.com
更新日期/Last Update: 2025-12-29