[1]张梓雄,乔文俊,张菁菁,等.宽体探测器 CT 冠状动脉血管成像中应用三低扫描成像技术的可行性分析[J].中国医学物理学杂志,2025,42(3):374-380.[doi:10.3969/j.issn.1005-202X.2025.03.014]
 ZHANG Zixiong,QIAO Wenjun,et al.Feasibility analysis of wide-detector CT coronary angiography using three-low scanning technology[J].Chinese Journal of Medical Physics,2025,42(3):374-380.[doi:10.3969/j.issn.1005-202X.2025.03.014]
点击复制

宽体探测器 CT 冠状动脉血管成像中应用三低扫描成像技术的可行性分析()
分享到:

《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
42
期数:
2025年第3期
页码:
374-380
栏目:
医学影像物理
出版日期:
2025-03-20

文章信息/Info

Title:
Feasibility analysis of wide-detector CT coronary angiography using three-low scanning technology
文章编号:
1005-202X(2025)03-0374-07
作者:
张梓雄 12乔文俊 2张菁菁 2杨蔓蔓 2陈佳轶 2周美娟 1
1. 南方医科大学公共卫生学院,广东 广州 510515;2. 南方医科大学南方医院医学影像中心,广东 广州 510515
Author(s):
ZHANG Zixiong1 2 QIAO Wenjun2 ZHANG Jingjing2 YANG Manman2 CHEN Jiayi2 ZHOU Meijuan1
1. School of Public Health, Southern Medical University, Guangzhou 510515, China; 2. Medical Imaging Center, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China
关键词:
冠状动脉三低扫描辐射剂量注射速率对比剂用量
Keywords:
coronary artery three-low scanning radiation dose injection rate contrast agent dosage
分类号:
R318R816
DOI:
10.3969/j.issn.1005-202X.2025.03.014
文献标志码:
A
摘要:
目的:分析不同扫描参数及对比剂注射方案,研究应用低辐射剂量、低注射速率及低对比剂用量的三低扫描成像技 术在宽体探测器 CT 冠状动脉血管成像中的可行性。方法:招募 210 例行冠状动脉血管成像的患者,并随机分为 A 组(常 规组,n=105)和 B 组(三低组,n=105),宽体探测器 CT 采用美国 GE 公司的 Revolution CT。A、B 组的管电压分别为 120、 100 kV;对比剂注射速率和注射用量分别依据身体质量指标及心率的计算。通过测量图像 CT 值、图像信噪比及对比噪声 比来客观评价图像质量;利用 Likert 5 分法进行主观图像质量评价。结果:两组基本资料信息比较,差异无统计学意义 (P>0.05);A 和 B 两组所得冠脉图像主动脉窦口 CT 值为(442.70±58.26)、(454.11±62.36)HU,两组图像 CT 值、图像评 分、图像信噪比及对比噪声比的差异无统计学意义(P>0.05),对比剂注射速率、对比剂用量、管电流、有效辐射剂量的差异 有统计学意义(P<0.05),B 组相比 A 组减少 33.89% 的有效辐射剂量。结论:基于患者身体质量指标及心率的个性化定制 对比剂注射方案,常规组及三低组均能获得满足影像诊断的图像质量,且三低组图像质量更优,即三低方案可在获得更优 质图像质量的前提下降低患者受照剂量和减少对比剂的使用,从而使患者获益更多。
Abstract:
Objective To analyze various scanning parameters and contrast agent injection schemes, and explore the feasibility of three-low scanning technology characterized by lower radiation dose, slower injection rate and reduced contrast agent dosage in coronary angiography with wide-detector CT. Methods A total of 210 patients who underwent coronary angiography were recruited and randomly divided into group A (routine group, n=105) and group B (three-low group, n= 105), and all of them were examined using the Revolution CT from the American GE company. Group A and group B adopted 120 and 100 kV tube voltages, respectively. The contrast injection rate and contrast agent dosage were calculated using formulas based on body mass index and beat per minute. Image quality was objectively evaluated using CT number, signal-tonoise ratio and contrast-to-noise ratio, and subjectively scored using Likert 5-point method. Results No statistical differences were found in the basic data between two groups (P>0.05). The CT numbers of the aortic sinus orifice in coronary artery images obtained from group A and group B were (442.70±58.26) and (454.11±62.36) HU, respectively. The differences between two groups in CT number, image score, signal-to-noise ratio, and contrast-to-noise ratio were trivial (P>0.05), while statistically significant differences were noted in injection rate, contrast agent dosage, tube current, and effective radiation dose (P<0.05). Group B reduced the effective radiation dose by 33.89% as compared with group A. Conclusion Based on the patient’s body mass index and beat per minute, a personalized contrast agent injection scheme can be developed. Both routine group and three-low group can obtain image quality that meets imaging diagnosis requirements, and the latter has better image quality, demonstrating that the three-low scheme benefits the patients more for it can reduce the patient’s radiation dose and contrast agent dosage while achieving higher image quality.

相似文献/References:

[1]程云章,胡嵬锋,罗文香,等.FFR值与冠动脉狭窄度的数值模拟[J].中国医学物理学杂志,2014,31(04):5066.[doi:10.3969/j.issn.1005-202X.2014.04.020]
[2]苏清秀,张 矛,金海国,等.比较调强放射治疗与三维适形放疗治疗中下段食管癌时心脏和冠状动脉的受量[J].中国医学物理学杂志,2014,31(05):5139.[doi:10.3969/j.issn.1005-202X.2014.05.010]
[3]张梦璐,杨孝平.基于改进活动窄带模型的冠状动脉CT血管造影图像分割[J].中国医学物理学杂志,2017,34(2):170.[doi:10.3969/j.issn.1005-202X.2017.02.012]
 Segmentation of CT angiographic images of the coronary artery based on an improved active narrow band model[J].Chinese Journal of Medical Physics,2017,34(3):170.[doi:10.3969/j.issn.1005-202X.2017.02.012]
[4]王力,孟庆民,郭永新,等. 基于Hessian矩阵的DSA图像冠状动脉直径的测量[J].中国医学物理学杂志,2019,36(10):1182.[doi:DOI:10.3969/j.issn.1005-202X.2019.10.013]
 WANG Li,MENG Qingmin,GUO Yongxin,et al. Measurement of coronary artery diameter on DSA image based on Hessian matrix[J].Chinese Journal of Medical Physics,2019,36(3):1182.[doi:DOI:10.3969/j.issn.1005-202X.2019.10.013]
[5]冯慧,吴钟伟,刘超权.冠心病患者心率变异性指标与冠状动脉病变程度的关系[J].中国医学物理学杂志,2019,36(12):1472.[doi:DOI:10.3969/j.issn.1005-202X.2019.12.021]
 FENG Hui,WU Zhongwei,LIU Chaoquan.Relationship between heart rate variability indexes and severity of coronary artery lesions in patients with coronary heart diseases[J].Chinese Journal of Medical Physics,2019,36(3):1472.[doi:DOI:10.3969/j.issn.1005-202X.2019.12.021]
[6]刘昊,王瑜,王怡宁,等.冠状动脉血管造影图像三维分割方法[J].中国医学物理学杂志,2021,38(7):826.[doi:DOI:10.3969/j.issn.1005-202X.2021.07.007]
 LIU Hao,WANG Yu,WANG Yining,et al.Three-dimensional segmentation method for coronary angiographic image[J].Chinese Journal of Medical Physics,2021,38(3):826.[doi:DOI:10.3969/j.issn.1005-202X.2021.07.007]
[7]王圣楠,卜荣生,杜静茹,等.CT-FFR参数联合斑块定量技术在心肌缺血再灌注损伤预测中的应用[J].中国医学物理学杂志,2023,40(1):66.[doi:DOI:10.3969/j.issn.1005-202X.2023.01.011]
 WANG Shengnan,BU Rongsheng,DU Jingru,et al.Predictive value of CT-FFR combined with plaque quantification for reperfusion injury in patients with myocardial ischemia[J].Chinese Journal of Medical Physics,2023,40(3):66.[doi:DOI:10.3969/j.issn.1005-202X.2023.01.011]
[8]刘珩,王雁南,那飞扬,等.低管电压联合ASiR-V算法“一站式”心脑血管CTA扫描模式的应用价值[J].中国医学物理学杂志,2023,40(2):176.[doi:DOI:10.3969/j.issn.1005-202X.2023.02.008]
 LIU Heng,WANG Yannan,NA Feiyang,et al.Clinical significance of one-stop cardio-cerebrovascular CTA scanning mode of low-tube voltage combined with ASiR-V algorithm[J].Chinese Journal of Medical Physics,2023,40(3):176.[doi:DOI:10.3969/j.issn.1005-202X.2023.02.008]

备注/Memo

备注/Memo:
【收稿日期】2024-11-12 【作者简介】张梓雄,硕士研究生,研究方向:医学成像,E-mail: 634987481@qq.com 【通信作者】周美娟,博士,教授,研究方向:放射医学,E-mail: 80758598@qq.com
更新日期/Last Update: 2025-03-27