[1]王垚,张焕芝,彭华康.磁感应热疗治疗肿瘤安全性研究进展[J].中国医学物理学杂志,2025,42(5):680-684.[doi:10.3969/j.issn.1005-202X.2025.05.019]
　WANG Yao,ZHANG Huanzhi,PENG Huakang.Research advances in the safety of magnetic induction hyperthermia in tumor treatment[J].Chinese Journal of Medical Physics,2025,42(5):680-684.[doi:10.3969/j.issn.1005-202X.2025.05.019]
点击复制

磁感应热疗治疗肿瘤安全性研究进展()

《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
42
期数:
2025年第5期
页码:
680-684
栏目:
医学生物物理
出版日期:
2025-05-20

文章信息/Info

Title:
Research advances in the safety of magnetic induction hyperthermia in tumor treatment
文章编号:
1005-202X（2025）05-0680-05
作者:
王垚1; 张焕芝2; 彭华康1
1.清华大学工程物理系，北京 100084；2.北京大学人民医院妇产科，北京 100044
Author(s):
WANG Yao1;  ZHANG Huanzhi2;  PENG Huakang1
1. Department of Engineering Physics, Tsinghua University, Beijing 100084, China; 2. Department of Gynaecology and Obstetrics, Peking University People’s Hospital, Beijing 100044, China
关键词:
磁感应热疗; 磁性纳米颗粒; 交变磁场; 综述
Keywords:
magnetic induction hyperthermia;  magnetic nanoparticle;  alternating magnetic field;  review
分类号:
R318；R730.5
DOI:
10.3969/j.issn.1005-202X.2025.05.019
文献标志码:
A
摘要:
磁感应热疗是一种利用交变磁场激发磁性纳米颗粒产生热量，进而破坏肿瘤细胞的非侵入性治疗方法。近年来，关于金属纳米颗粒的生物安全性、交变磁场的潜在影响以及磁感应热疗在肿瘤治疗中的安全性问题已成为研究热点。本文综述了金属纳米颗粒在生物体内的代谢以及其潜在的毒性问题，探讨交变磁场对正常细胞和组织的影响，并总结了磁感应热疗在临床应用中的安全性和有效性研究。通过深入分析这些关键问题，旨在提高临床医生和研究人员对磁感应热疗安全性的认识，促进其在肿瘤治疗中的合理应用，以期为患者带来更安全、更有效的治疗方案。
Abstract:
Magnetic induction hyperthermia is a non-invasive therapeutic method that utilizes an alternating magnetic field to excite magnetic nanoparticles to generate heat, thereby destroying tumor cells. In recent years, the biosafety of metal nanoparticles, the potential impact of alternating magnetic fields, and the safety issues of magnetic induction hyperthermia in the treatment of tumors have become research hot topics. The review introduces the metabolism of metal nanoparticles in the body and their potential toxicity, discusses the effects of alternating magnetic fields on normal cells and tissues, and summarizes the researches on the safety and efficacy of magnetic induction hyperthermia in clinical applications. Through indepth analysis of these key issues, the aim is to enhance the understanding of the safety of magnetic induction hyperthermia among clinical physicians and researchers, and promote its rational application in tumor treatment, thus providing patients with safer and more effective treatment schemes.

相似文献/References:

[1]张恒,逯迈.磁感应热疗作用于胰腺癌模型热场分布[J].中国医学物理学杂志,2023,40(11):1408.[doi:DOI:10.3969/j.issn.1005-202X.2023.11.015]
　ZHANG Heng,LU Mai.Thermal field distribution of pancreatic cancer model treated with magnetic induction hyperthermia[J].Chinese Journal of Medical Physics,2023,40(5):1408.[doi:DOI:10.3969/j.issn.1005-202X.2023.11.015]
[2]郭思玮,逯迈.大鼠磁感应热疗的线圈设计与仿真分析[J].中国医学物理学杂志,2024,41(1):101.[doi:DOI:10.3969/j.issn.1005-202X.2024.01.015]
　GUO Siwei,LU Mai.Coil design and simulation analysis of magnetic induction hyperthermia in rats[J].Chinese Journal of Medical Physics,2024,41(5):101.[doi:DOI:10.3969/j.issn.1005-202X.2024.01.015]

备注/Memo

备注/Memo:
【收稿日期】2024-12-05【作者简介】王垚，博士，助理研究员，研究方向：肿瘤物理治疗，E-mail: 13426453645@qq.com
更新日期/Last Update: 2025-06-03