[1]曹潘潘,王维青,成宇,等.个体化塑形的鼻咽癌多感兴趣区图像配准摆位误差[J].中国医学物理学杂志,2024,41(2):151-157.[doi:DOI:10.3969/j.issn.1005-202X.2024.02.004]
　CAO Panpan,WANG Weiqing,CHENG Yu,et al.Setup error analysis of image registration using various regions of interest after individualized nasopharyngeal carcinoma radiotherapy immobilization[J].Chinese Journal of Medical Physics,2024,41(2):151-157.[doi:DOI:10.3969/j.issn.1005-202X.2024.02.004]
点击复制

个体化塑形的鼻咽癌多感兴趣区图像配准摆位误差()
分享到：

《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
41卷
期数:
2024年第2期
页码:
151-157
栏目:
医学放射物理
出版日期:
2024-03-13

文章信息/Info

Title:
Setup error analysis of image registration using various regions of interest after individualized nasopharyngeal carcinoma radiotherapy immobilization
文章编号:
1005-202X（2024）02-0151-07
作者:
曹潘潘1; 王维青2; 成宇1; 雷金艳1; 李师1; 施小龙1; 彭海燕1; 靳富1
1.重庆大学附属肿瘤医院放射物理中心， 重庆 400030； 2.临沂市第三人民医院影像科， 山东 临沂 276000
Author(s):
CAO Panpan1;  WANG Weiqing2;  CHENG Yu1;  LEI Jinyan1;  LI Shi1;  SHI Xiaolong1;  PENG Haiyan1;  JIN Fu1
1. Radiation Physics Center, Chongqing University Cancer Hospital, Chongqing 400030, China 2. Department of Imaging, Linyi Third Peoples Hospital, Linyi 276000, China
关键词:
鼻咽癌; 个体化塑形; 多感兴趣区; 摆位误差
Keywords:
Keywords: nasopharyngeal carcinoma individualized immobilization multiple regions of interest setup error
分类号:
R318；R811.1
DOI:
DOI:10.3969/j.issn.1005-202X.2024.02.004
文献标志码:
A
摘要:
目的：探究鼻咽癌个体化塑形多感兴趣区图像配准对摆位误差的影响。方法：随机选取43例鼻咽癌放疗的患者，采用发泡胶个体化塑形联合头颈肩热塑膜对其进行体位固定，每周一次CBCT摆位校准。在CBCT图像上，将感兴趣区（ROI）划分为临床使用的全ROI（ROIPTV）和7个包含不同颈段结构的局部ROI（ROI蝶窦、ROI寰枢椎、ROI颈3、ROI颈4、ROI颈5、ROI颈6、ROI颈7），分别与定位CT图像配准，记8个ROI在头脚（SI)、左右（LR）、腹背（AP）、Pitch、Roll、Yaw方向的配准误差。结果：SI方向ROI颈7的摆位误差在0.3 cm以内的占89.74%，其余ROI在0.3 cm以内均占90%以上。LR方向随着颈段往上，摆位误差在0.3 cm以内的占比逐渐增加，ROI颈7、ROI颈6、ROI颈5摆位误差在0.3 cm以内的占比分别为76.78%、81.70%和85.26%，其余ROI占比均在90%以上；AP方向除ROI寰枢椎和ROI颈3外，其余ROI摆位误差在0.3 cm以内的占比均低于90%。ROI蝶窦、ROI寰枢椎、ROI颈3、ROI颈4与ROIPTV在SI方向的摆位误差均呈显著正相关（R=0.94、0.95、0.90、0.83）；ROI蝶窦与ROI寰枢椎、ROI颈3，ROIPTV与ROI颈3在LR方向的摆位误差均呈显著正相关（R=0.95、0.91、0.91）；AP方向ROIPTV与ROI寰枢椎、ROI颈3的摆位误差均呈显著正相关（R=0.88、0.90）。8个ROI的外扩为0.38~1.01 cm，其中ROI颈6与ROI颈7在AP方向的外扩均超过0.90 cm，ROI颈7在SI方向的外扩达到0.95 cm。结论：ROIPTV与ROI蝶窦、ROI寰枢椎、ROI颈3在SI、LR和AP方向均存在显著相关性；随着颈段从第三颈椎往下，鼻咽癌患者分段摆位误差逐渐增大；头颈部鼻咽癌患者用发泡胶进行个体化塑形时，鼻咽部和颈椎区域需分段进行外扩。
Abstract:
Abstract: Objective To explore the effects of image registration using various regions of interest (ROI) on the setup error for nasopharyngeal carcinoma (NPC) patients who were immobilized individually. Methods Forty-three NPC patients who required radiotherapy were enrolled. The patients were immobilized with customized plastic foam and thermoplastic mask, and CBCT verification was performed once a week. In CBCT images, ROI was divided into the whole ROI (ROIPTV) and 7 local ROI containing different cervical structures (ROIsphenoid sinus, ROIatlantoaxial, ROIneck3, ROIneck4, ROIneck5, ROIneck6, and ROIneck7), which were then used for registrations with localized CT image. The setup errors in superior-inferior (SI), left-right (LR), anterior-posterior (AP), Pitch, Roll, and Yaw directions were recorded. Results In SI direction, the setup errors within 0.3 cm accounted for 89.74% for ROIneck7, and more than 90% for the other ROI. The proportion of setup errors within 0.3 cm gradually increased with the neck upward in LR direction, and they were 76.78%, 81.70%, 85.26%, and above 90% for ROIneck7, ROIneck6, ROIneck5, and the other ROI, respectively. In AP direction, the proportions of setup errors within 0.3 cm were less than 90%, except for ROIatlantoaxial and ROIneck3. The setup errors of ROIsphenoid sinus, ROIatlantoaxial, ROIneck3, and ROIneck4 were significantly positively correlated with ROIPTV in SI direction, and the correlation coefficients (R) were 0.94, 0.95, 0.90, and 0.83, respectively. In LR direction, there were positive correlations between the setup errors of ROIatlantoaxial and ROIsphenoid sinus (R=0.95), ROIneck3 and ROIsphenoid sinus (R=0.91), ROIPTV and ROIneck3 (R=0.91). The setup errors of ROIPTV in AP direction were positively correlated with ROIatlantoaxial vertebrae and ROIneck3 (R=0.88, 0.90). The margins of all ROIs ranged from 0.38 cm to 1.01 cm. The extension of ROIneck6 and ROIneck7 in AP direction exceeded 0.9 cm, and the extension of ROIneck7 reached 0.95 cm in SI direction. Conclusion ROIPTV and ROIsphenoid sinus, ROIatlantoaxial, ROIneck3 are significantly correlated in SI, LR, and AP directions. The setup error of nasopharyngeal carcinoma patients gradually increases with the neck down. The nasopharyngeal and cervical regions need to be expanded in segments when patients are immobilized individually.

相似文献/References:

[1]陈广涛,汪 淇,刘亚强,等.TrueBeam加速器射野准直器跟随功能在鼻咽癌固定野调强放疗和容积旋转调强放疗中的应用[J].中国医学物理学杂志,2014,31(03):4865.[doi:10.3969/j.issn.1005-202X.2014.03.005]
[2]潘宇辉,陈榕钦,柏朋刚,等.鼻咽癌调强放射治疗前后腮腺体积及空间几何位置变化研究[J].中国医学物理学杂志,2014,31(05):5120.[doi:10.3969/j.issn.1005-202X.2014.05.005]
[3]张俊俊,邱小平,李奇欣,等.ArcCheck系统在鼻咽癌容积旋转调强剂量验证中的应用[J].中国医学物理学杂志,2014,31(05):5136.[doi:10.3969/j.issn.1005-202X.2014.05.009]
[4]桑 勇,陈维军,狄小云,等.多叶光栅叶片宽度对鼻咽癌剂量学的影响[J].中国医学物理学杂志,2014,31(06):5240.[doi:10.3969/j.issn.1005-202X.2014.06.004]
[5]黄利生,庄婷婷,伍方财,等.鼻咽癌调强放疗Ib区剂量分析[J].中国医学物理学杂志,2014,31(06):5265.[doi:10.3969/j.issn.1005-202X.2014.06.010]
[6]易金玲,金献测,周永强,等.鼻咽癌IMRT与VMAT治疗的计划与剂量验证比较研究[J].中国医学物理学杂志,2013,30(01):3859.[doi:10.3969/j.issn.1005-202X.2013.01.006]
[7]金献测,易金玲,周永强,等.鼻咽癌同步加量调强放射治疗新的计划质量评估指标研究[J].中国医学物理学杂志,2013,30(02):3978.[doi:10.3969/j.issn.1005-202X.2013.02.004]
[8]蒋晓芹,段宝风,艾平,等.基于图谱库的自动轮廓勾画软件(ABAS)在鼻咽癌调强放疗中的应用[J].中国医学物理学杂志,2013,30(02):3997.[doi:10.3969/j.issn.1005-202X.2013.02.008]
[9]张达光,蒋胜鹏,李智华,等.鼻咽癌调强放疗中解剖结构改变及剂量分布变化的研究[J].中国医学物理学杂志,2013,30(04):4239.[doi:10.3969/j.issn.1005-202X.2013.04.006]
[10]杨海燕,王军良,周振山,等.AAA算法和PBC算法在鼻咽癌调强放疗中剂量分布的比较[J].中国医学物理学杂志,2013,30(04):4245.[doi:10.3969/j.issn.1005-202X.2013.04.008]

备注/Memo

备注/Memo:
【收稿日期】2023-11-12 【基金项目】重庆市科卫联合医学科研项目（2022DBXM005） 【作者简介】曹潘潘，主管技师，研究方向：肿瘤放射治疗，E-mail: p18623193021@163.com 【通信作者】彭海燕，主管技师，研究方向：肿瘤放射治疗，E-mail: 13668175902@163.com
更新日期/Last Update: 2024-02-27