[1]潘奇峰.超声心动图联合cTnl、NT-pro BNP、D-二聚体在心血管急症诊断中的应用[J].中国医学物理学杂志,2023,40(5):576-579.[doi:DOI:10.3969/j.issn.1005-202X.2023.05.009]
　PAN Qifeng.Diagnostic value of echocardiogram combined with cTnl, NT-pro BNP and D-dimer for cardiovascular emergencies[J].Chinese Journal of Medical Physics,2023,40(5):576-579.[doi:DOI:10.3969/j.issn.1005-202X.2023.05.009]
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超声心动图联合cTnl、NT-pro BNP、D-二聚体在心血管急症诊断中的应用()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
40卷
期数:
2023年第5期
页码:
576-579
栏目:
医学影像物理
出版日期:
2023-05-26

文章信息/Info

Title:
Diagnostic value of echocardiogram combined with cTnl, NT-pro BNP and D-dimer for cardiovascular emergencies
文章编号:
1005-202X（2023）05-0576-04
作者:
潘奇峰
梧州市工人医院心内科， 广西 梧州 543001
Author(s):
PAN Qifeng
Department of Cardiology, Wuzhou Gongren Hospital, Wuzhou 543001, China
关键词:
超声心动图; 肌钙蛋白; 氨基末端脑钠肽前体; D-二聚体; 心血管急症
Keywords:
Keywords: echocardiogram cardiac troponin amino-terminal pro-brain natriuretic peptide D-dimer cardiovascular emergencies
分类号:
R541
DOI:
DOI:10.3969/j.issn.1005-202X.2023.05.009
文献标志码:
A
摘要:
目的：探讨并分析超声心动图联合肌钙蛋白（cTnl）、氨基末端脑钠肽前体（NT-pro BNP）、D-二聚体（D-D）检测在心血管急症诊断中的应用。方法：回顾性分析180例心血管急症患者，根据疾病类型不同分为急性心肌梗死（AMI）组（n=52）、急性心力衰竭（AHF）组（n=63）、急性主动脉夹层（AAD）组（n=28）及急性肺栓塞（APE）组（n=37）。采用超声心动图对所有患者予以检查，记录左室射血分数（LVEF）、左心室舒张末期内径值（LVEDd）及左心室收缩期末容积（LVESV）；使用酶联免疫吸附试验法检测并比较患者的cTnl、NT-pro BNP及D-D水平，并记录4组患者在30 d内的生存率，采用受试者操作特征（ROC）曲线分析LVEF、cTnl、NT-pro BNP、D-D及其联合检测对心血管急症生存情况的诊断效能。结果：AMI组患者cTnl水平显著高于AAD组与APE组，D-D水平显著低于AAD组与APE组（P<0.05）；AHF组患者NT-pro BNP水平显著高于AMI组、AAD组与APE组（P<0.05）。AMI组患者LVEF水平显著低于AHF组、AAD组和APE组（P<0.05），LVEDd、LVESV水平显著高于AHF组、AAD组和APE组（P<0.05）。AMI组、AHF组、AAD组及APE组30 d内的生存率分别为90.38%、90.48%、89.29%及91.89%（P>0.05）。ROC曲线显示cTnl、NT-pro BNP、D-D、LVEF、LVEDd、LVESV及其联合检测在诊断心血管急症患者生存中的ROC曲线下面积（AUC）分别为0.680、0.733、0.656、0.708、0.656、0.663、0.886。结论：超声心动图联合cTnl、NT-pro BNP、D-D在心血管急症诊断中有一定应用价值。
Abstract:
Abstract: Objective To explore and analyze the value of echocardiogram combined with cardiac troponin (cTnl), amino-terminal pro-brain natriuretic peptide (NT-pro BNP) and D-dimer (D-D) in the diagnosis of cardiovascular emergencies. Methods A retrospective analysis was performed on the 180 patients with acute cardiovascular diseases. According to different disease types, they were divided into acute myocardial infarction (AMI) group (n=52), acute heart failure (AHF) group (n=63), acute aortic dissection (AAD) group (n=28) and acute pulmonary embolism (APE) group (n=37). All underwent echocardiography for recording their left ventricular ejection fraction (LVEF), left ventricular end-diastolic diameter (LVEDd) and left ventricular end-systolic volume (LVESV). The levels of cTnl, NT-pro BNP and D-D were detected using enzyme-linked immunosorbent assay. The survival rates within 30 d in the 4 groups were compared, and the diagnostic efficiencies of LVEF, cTnl, NT-pro BNP, D-D and combined detection for cardiovascular emergencies were analyzed using receiver operating characteristic (ROC) curves. Results Compared with AAD and APE groups, AMI group had a higher cTnl level and lower D-D level (P<0.05). The NT-pro BNP level in AHF group was significantly higher than that in AMI, AAD and APE groups (P<0.05). LVEF level was lower, and LVEDd and LVESV levels were higher in AMI group as compared with AHF, AAD and APE groups (P<0.05). The 30 d survival rates in AMI, AHF, AAD and APE groups were 90.38%, 90.48%, 89.29% and 91.89%, respectively (P>0.05) and cTnl, NT-pro BNP, D-D, LVEF, LVEDd, LVESV and combined detection had an AUC of 0.680, 0.733, 0.656, 0.708, 0.656, 0.663 and 0.886 for the diagnosis of cardiovascular emergencies. Conclusion The combination of echocardiogram with cTnl, NT-pro BNP and D-D is of great value in diagnosing cardiovascular emergencies.

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备注/Memo

备注/Memo:
【收稿日期】2022-12-07 【基金项目】梧州市科技计划项目（202002077） 【作者简介】潘奇峰，副主任医师，研究方向：心血管内科，E-mail: dyx192015@163.com
更新日期/Last Update: 2023-05-26