3D-PDI相关参数对体外受精-胚胎移植妊娠结局的预测价值-《中国医学物理学杂志》

文章信息/Info

Title:: Predictive value of 3D-PDI parameters for pregnancy outcomes after in vitro fertilization-embryo transfer

文章编号:: 1005-202X（2023）06-0709-05

作者:: 刘环1; 努尔艾力·木台力甫1; 努尔比耶·图尔迪1; 丁芸2; 1.喀什地区第一人民医院超声医学科，新疆喀什 844000； 2.喀什地区第一人民医院招标办，新疆喀什 844000

Author(s):: LIU Huan1; NUERAILI Mutailifu1; NUERBIYE Tuerdi1; DING Yun2; 1. Department of Ultrasound Medicine, The First Peoples Hospital of Kashgar, Kashgar 844000, China 2. Department of Tender, The First Peoples Hospital of Kashgar, Kashgar 844000, China

关键词:: 体外受精; 胚胎移植; 助孕; 经阴道三维能量多普勒血流显像超声; 妊娠结局; 受试者工作特征曲线

Keywords:: Keywords: in vitro fertilization embryo transfer assisted reproduction transvaginal three-dimensional power Doppler imaging pregnancy outcome receiver operating characteristic curve

分类号:: R714.8

DOI:: DOI:10.3969/j.issn.1005-202X.2023.06.007

文献标志码:: A

摘要:: 目的：分析三维能量多普勒血流显像超声（3D-PDI）相关参数对体外受精-胚胎移植（IVF-ET）妊娠结局的预测价值。方法：以2021年12月~2022年3月收治的IVF-ET助孕患者100例为研究对象，所有患者均进行IVF-ET助孕，后进行3D-PDI检查。根据患者IVF-ET后14 d孕酮水平将其分为孕酮升高组（34例）和孕酮正常组（66例），比较两组3D-PDI检查的相关参数；根据患者是否成功妊娠将患者分为妊娠组（47例）和未妊娠组（53例），比较两组3D-PDI检查的相关参数。绘制受试者工作特征（ROC）曲线获取曲线下面积（AUC），分析3D-PDI检查的相关参数单独及联合对IVF-ET助孕患者妊娠结局的预测价值。结果：孕酮升高组子宫内膜回声分型A型、B型及内膜血流分型Ⅱ型、Ⅲ型患者占比（20.59%、32.35%和20.59%、14.71%）低于孕酮正常组（33.33%、42.42%和37.88%、30.30%）（P<0.05），子宫内膜回声分型C型及内膜血流分型Ⅰ型患者占比（47.06%和64.71%）高于孕酮正常组（24.24%和31.82%）（P<0.05）；孕酮升高组内膜厚度、容积、血管化指数（VI）、血管化血流指数（VFI）、血流指数（FI）均低于孕酮正常组（P<0.05）。妊娠组内膜容积、VI、VFI、FI高于未妊娠组（P<0.05）。ROC曲线分析结果显示内膜容积、VI、VFI、FI联合对预测IVF-ET助孕患者妊娠结局AUC及敏感度均高于其单独预测（P<0.05）。结论：IVF-ET助孕患者内膜容积、VI、VFI、FI升高有助于患者成功妊娠，同时4者联合对IVF-ET助孕患者妊娠结局具有良好的预测价值。

Abstract:: Abstract: Objective To analyze the value of three-dimensional power Doppler imaging (3D-PDI) parameters to predict the pregnancy outcomes after in vitro fertilization-embryo transfer (IVF-ET). Methods A total of 100 patients treated with IVF-ET from December 2021 to March 2022 were enrolled. All patients underwent IVF-ET followed by 3D-PDI. According to the progesterone level on day 14 after IVF-ET, the patients were divided into progesterone elevation group (n=34) and normal progesterone group (n=66), and the relevant parameters of 3D-PDI were compared between the two groups. According to whether the pregnancy was successful or not, the patients were divided into pregnant group (n=47) and non-pregnant group (n=53), and the relevant parameters of 3D-PDI were compared between the two groups. The area under the receiver operating characteristic curve (AUC) was used to analyze the predictive value of 3D-PDI parameters alone and in combination for pregnancy outcomes after IVF-ET. Results The proportions of endometrial echo types A and B and endometrial blood flow types Ⅱ and Ⅲ in progesterone elevation group were 20.59%, 32.35%, 20.59%, 14.71%, respectively, lower than those in normal progesterone group (33.33%, 42.42%, 37.88%, 30.30%, respectively) (P<0.05). The endometrial echo type C and endometrial blood flow type Ⅰ were observed in 47.06% and 64.71% of patients in progesterone elevation group, and in 24.24% and 31.82% of patients in normal progesterone group (P<0.05). Progesterone elevation group had lower intimal thickness, volume, vascularization index (VI), vascularization flow index (VFI) and blood flow index (FI) than normal progesterone group (P<0.05). The endometrial volume, VI, VFI and FI of pregnant group were higher than those of non-pregnant group (P<0.05). Compared with parameter alone, the combination of endometrial volume, VI, VFI and FI had higher AUC and sensitivity for predicting pregnancy outcome after IVF-ET (P<0.05). Conclusion The increase of intimal volume, VI, VFI and FI in IVF-ET patients is helpful to the successful pregnancy, and their combination has a high predictive value for the pregnancy outcome after IVF-ET.

《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

文章信息/Info

备注/Memo

常用功能

导航/Navigate

工具/Tools

统计/Statistics