[1]张国梁,王利顺,李伟伟,等.超声、磁共振及染色体基因检测联合诊断胎儿颅脑异常的临床价值[J].中国医学物理学杂志,2023,40(8):985-987.[doi:DOI:10.3969/j.issn.1005-202X.2023.08.010]
　ZHANG Guoliang,WANG Lishun,LI Weiwei,et al.Roles of ultrasound, MRI and chromosomal gene detection in the diagnosis of fetal brain abnormalities[J].Chinese Journal of Medical Physics,2023,40(8):985-987.[doi:DOI:10.3969/j.issn.1005-202X.2023.08.010]
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超声、磁共振及染色体基因检测联合诊断胎儿颅脑异常的临床价值()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
40卷
期数:
2023年第8期
页码:
985-987
栏目:
医学影像物理
出版日期:
2023-09-01

文章信息/Info

Title:
Roles of ultrasound, MRI and chromosomal gene detection in the diagnosis of fetal brain abnormalities
文章编号:
1005-202X（2023）08-0985-03
作者:
张国梁; 王利顺; 李伟伟; 华天书; 王启臣; 赵瑶瑶
秦皇岛市妇幼保健院放射科， 河北 秦皇岛 066000
Author(s):
ZHANG Guoliang;  WANG Lishun;  LI Weiwei;  HUA Tianshu;  WANG Qichen;  ZHAO Yaoyao
Department of Radiology, Maternal and Child Care Center of Qinhuangdao, Qinhuangdao 066000, China
关键词:
胎儿发育异常; 超声; 磁共振; 染色体基因检测; 联合诊断
Keywords:
Keywords: fetal dysplasia ultrasound magnetic resonance imaging chromosomal gene detection combined diagnosis
分类号:
R714.2
DOI:
DOI:10.3969/j.issn.1005-202X.2023.08.010
文献标志码:
A
摘要:
目的：探讨超声（US）、磁共振（MRI）及染色体基因检测联合诊断胎儿颅脑异常的临床价值。方法：回顾性分析影像检查提示胎儿颅内可能存在异常的孕妇120例作为研究对象。通过对胎儿染色体微阵列分析（CMA）及颅脑US、MRI检查比较，对MRI与US的诊断结果符合率进行分析。结果：MRI与US诊断结果符合率差异无统计学意义（P>0.05）。US、MRI及CMA联合诊断结果中，特异性90.83%，灵敏性90.00%，假阳性10.83%，假阴性10.00%。结论：US、MRI可有效诊断胎儿颅内发育异常情况；MRI较US对透明隔间腔检查占优；有指征的孕妇应该进行US、MRI及CMA联合诊断。
Abstract:
Abstract: Objective To explore the clinical value of the combination of ultrasound (US), magnetic resonance imaging (MRI) and chromosomal gene detection in the diagnosis of fetal brain abnormalities. Methods A retrospective analysis was carried out on 120 pregnant women with imaging findings suggesting possible brain abnormalities in the fetuses. The diagnosis rates of MRI and US were analyzed by comparing fetal chromosome microarray analysis (CMA) with brain US and MRI. Results There was no significant difference between MRI and US in diagnosis rate (P>0.05). The combination of US, MRI and CMA had a specificity of 90.83%, sensitivity of 90.00%, false positive rate of 10.83% and false negative rate of 10.00% for the diagnosis of fetal brain abnormalities. Conclusion Both US and MRI can effectively diagnose fetal brain abnormalities, but MRI is superior over US in the detection of cavity of septum pellucidum. US, MRI and CMA should be combined for pregnant women with the corresponding indications.

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备注/Memo

备注/Memo:
【收稿日期】2022-10-21 【基金项目】河北省医学科学研究项目（20191390） 【作者简介】张国梁，主治医师，研究方向：盆底障碍性疾病，E-mail: zgl202208@163.com 【通信作者】王利顺，副主任医师，研究方向：盆底功能障碍性疾病，E-mail: 1015530918@qq.com
更新日期/Last Update: 2023-09-06