j.issn.1005-202X.2023.01.003]
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EBT3胶片数字化的横向响应伪影消除方法()

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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

Title:: Eliminating lateral response artifact for EBT3 radiochromic film digitization

作者:: 白凯1; 2; 3; 4; 张鹏程5; 黄盛聪2; 3; 4; 祁宁5; 李强2; 3; 4; 刘新国2; 3; 4; 1.兰州大学核科学与技术学院，甘肃兰州 730000； 2.中国科学院近代物理研究所，甘肃兰州 730000； 3.中国科学院重离子束辐射生物医学重点实验室，甘肃兰州 730000； 4.甘肃省重离子束辐射医学应用基础重点实验室，甘肃兰州 730000； 5.兰州大学第一医院放疗科，甘肃兰州 730000

Author(s):: BAI Kai1; 2; 3; 4; ZHANG Pengcheng5; HUANG Shengcong2; 3; 4; QI Ning5; LI Qiang2; 3; 4; LIU Xinguo2; 3; 4; 1. School of Nuclear Science and Technology, Lanzhou University, Lanzhou 730000, China 2. Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000, China 3. Key Laboratory of Heavy Ion Radiation Biology and Medicine of Chinese Academy of Sciences, Lanzhou 730000, China 4. Gansu Provincial Key Laboratory of Basic Research on Heavy Ion Radiation Application in Medicine, Lanzhou 730000, China 5. Department of Radiotherapy, the First Hospital of Lanzhou University, Lanzhou 730000, China

Keywords:: Keywords: EBT3 radiochromic film digitization anti-reflective glass lateral response artifact net optical density

摘要:: 目的：消除EBT3胶片数字化过程中的横向响应伪影，优化EBT3胶片的治疗计划验证结果。方法：覆盖双面镀膜的减反射玻璃进行胶片数字化，通过净光密度与扫描仪不同位置间的抛物线拟合关系来消除横向响应伪影后，借助剂量刻度曲线将胶片净光密度转换为剂量。使用辐照面积较大的治疗计划进行验证，对胶片与计划剂量分布进行γ分析。结果：在3%/3 mm标准下对不小于0.1 Gy的剂量点进行γ分析，消除横向响应伪影后胶片与计划剂量分布的γ通过率为95%，相比未消除横向响应伪影的剂量分布提升了3%的通过率。结论：利用该方法可以有效消除横向响应伪影，提高EBT3胶片治疗计划验证的γ通过率。

Abstract:: Abstract: Objective To eliminate the lateral response artifact during EBT3 radiochromic film digitization and optimize the treatment plan verification results using EBT3 film. Methods The EBT3 films were digitalized with a scanner covered with a double-side coated anti-reflective glass. The lateral response artifact was eliminated using the parabola function which was obtained by fitting the relationship between the net optical densities and their positions on the scanner window. Then the net optical densities were converted into doses via dose calibration curve. The method was tested with a QA plan with a large irradiation field, and the gamma-index distribution was analyzed. Results The gamma passing rate (3%/3 mm, for dose greater than or equal 0.1 Gy) between planned dose profile and corrected film dose profile was 95% which was 3% higher than the uncorrected film dose profile. Conclusion The proposed method can effectively eliminate the lateral response artifact and improve the gamma passing rate of QA plan verification using EBT3 film.

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备注/Memo:: 【收稿日期】2022-07-26 【基金项目】中国科学院西部之光项目（29Y86205）；中国科学院重点部署项目（KFZD-SW-222）；甘肃省自然科学基金（18JR3RA390）【作者简介】白凯，硕士研究生，研究方向：重离子束治疗基础技术，E-mail: 287793294@qq.com 【通信作者】刘新国，高级工程师，研究方向：重离子束治疗基础技术，E-mail: liuxinguo@impcas.ac.cn

更新日期/Last Update: 2023-01-07