[1]史亚滨,黄嵘,高艳,等.左侧乳腺癌保乳术后深吸气屏气模式下Hybrid-IMRT和Hybrid-VMAT的剂量学比较[J].中国医学物理学杂志,2022,39(8):936-940.[doi:DOI:10.3969/j.issn.1005-202X.2022.08.003]
　SHI Yabin,HUANG Rong,GAO Yan,et al.Dosimetric comparison between Hybrid-IMRT and Hybrid-VMAT using deep inspiration breath-hold technique for left-sided breast cancer after breast-conserving surgery[J].Chinese Journal of Medical Physics,2022,39(8):936-940.[doi:DOI:10.3969/j.issn.1005-202X.2022.08.003]
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左侧乳腺癌保乳术后深吸气屏气模式下Hybrid-IMRT和Hybrid-VMAT的剂量学比较()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
39卷
期数:
2022年第8期
页码:
936-940
栏目:
医学放射物理
出版日期:
2022-08-04

文章信息/Info

Title:
Dosimetric comparison between Hybrid-IMRT and Hybrid-VMAT using deep inspiration breath-hold technique for left-sided breast cancer after breast-conserving surgery
文章编号:
1005-202X（2022）08-0936-05
作者:
史亚滨1; 2; 黄嵘3; 高艳2; 陈洪涛2; 徐逸4; 陈伟思2; 梁晓敏2; 郑芳2
1.汕头大学医学院， 广东 汕头 515041； 2.深圳市人民医院（暨南大学第二临床医学院，南方科技大学第一附属医院）肿瘤放疗科， 广东 深圳 518020； 3.北京大学深圳医院影像科， 广东 深圳 518036； 4.深圳市第三人民医院感染二科， 广东 深圳 518112
Author(s):
SHI Yabin1; 2;  HUANG Rong3;  GAO Yan2;  CHEN Hongtao2;  XU Yi4;  CHEN Weisi2;  LIANG Xiaomin2;  ZHENG Fang2
1.Shantou University Medical College, Shantou 515041, China 2.Department of Radiation Oncology, Shenzhen Peoples Hospital?the Second Clinical Medical College, Jinan University the First Affiliated Hospital of Southern University of Science and Technology), Shenzhen 518020, China 3. Department of Radiology, Peking University Shenzhen Hospital, Shenzhen 518036, China 4. the Second Department of?nfectious?isease, the Third Peoples Hospital of Shenzhen, Shenzhen 518112, China
关键词:
乳腺癌; 深吸气屏气; 混合调强; 混合旋转容积调强; 剂量学
Keywords:
Keywords: breast cancer deep inspiration breath-hold hybrid intensity-modulated radiotherapy hybrid volumetric modulated arc therapy dosimetry
分类号:
R737.9；R811.1
DOI:
DOI:10.3969/j.issn.1005-202X.2022.08.003
文献标志码:
A
摘要:
目的：在深吸气屏气（DIBH）模式下比较适形混合调强（Hybrid-IMRT）和适形混合旋转容积调强（Hybrid-VMAT）对左侧乳腺癌保乳术后的剂量学差异，为治疗计划选择提供参考。方法：选取26名左侧乳腺癌保乳术后的患者分别设计Hybrid-IMRT和Hybrid-VMAT计划，通过体积剂量直方图比较两种计划的靶区和危及器官的剂量。结果：Hybrid-VMAT计划PTV的D90、D98及HI优于Hybrid-IMRT计划（P<0.05）。Hybrid-IMRT计划GI优于Hybrid-VMAT计划（P<0.05），但对于PTV的D2、Dmean及CI，两种计划没有明显差异（P>0.05）。Hybrid-IMRT计划患侧肺V5、V20、V30及Dmean优于Hybrid-VMAT计划（P<0.05）； Hybrid-IMRT计划心脏的V10、Dmean优于Hybrid-VMAT计划（P<0.05），但V30、V40比较，差异无统计学意义（P>0.05）；Hybrid-IMRT计划对侧乳腺Dmean、V5优于Hybrid-VMAT计划（P<0.05），但Dmax比较，差异无统计学意义（P>0.05）；两种计划的脊髓剂量均满足临床剂量要求，但Hybrid-IMRT计划的脊髓Dmax低于Hybrid-VMAT计划（P<0.05）。结论：两种混合计划均能满足临床剂量要求，但Hybrid-IMRT计划可以明显降低危及器官的受照剂量。
Abstract:
Abstract: Objective To compare the dosimetric differences between hybrid intensity-modulated radiotherapy (Hybrid-IMRT) and hybrid volumetric modulated arc therapy (Hybrid-VMAT) using deep inspiration breath-hold (DIBH) technique for left-sided breast cancer after breast-conserving surgery, thereby providing reference for treatment plan selection. Methods Two kinds of treatment plans, namely Hybrid-IMRT plan and Hybrid-VMAT plan, were designed for 26 patients with left-sided breast cancer after breast-conserving surgery. The dose-volume histogram was used to compare the doses to target areas and organs-at-risk between Hybrid-IMRT plan and Hybrid-VMAT plan. Results Compared with Hybrid-IMRT plan, Hybrid-VMAT plan was superior in D90, D98 and homogeneity index of planning target area (P<0.05), but inferior in GI (P<0.05), and there was no significant difference in D2, CI and Dmean between two plans (P>0.05). Hybrid-IMRT plan was advantageous over Hybrid-VMAT plan in terms of the V5, V20, V30 and Dmean of the ipsilateral lung (P<0.05), and the V10, Dmean of the heart (P<0.05). However, there was no significant difference between two plans in the V40 and V30 of the heart (P>0.05). Hybrid-IMRT plan was superior to Hybrid-VMAT plan in the Dmean and V5 of contralateral breast (P<0.05), but the difference in Dmax was trivial (P>0.05). The spinal dose of the two plans met the clinical dose requirements, while the spinal Dmax of Hybrid-IMRT plan was much less than that of Hybrid-VMAT plan (P<0.05). Conclusion Both of the two hybrid plans meet the clinical dose requirements, but Hybrid-IMRT plan can significantly reduce the radiation dose to organs-at-risk.

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备注/Memo

备注/Memo:
【收稿日期】2022-04-01 【基金项目】广东省医学科研基金（B2021395） 【作者简介】史亚滨，硕士研究生，主要从事放射医学物理研究，E-mail: 236212481@qq.com 【通信作者】黄嵘，主任医师，主要从事放射诊断研究，E-mail: huangrong_sz@qq.com
更新日期/Last Update: 2022-09-05