[1]王耀辉,吕喆,张重阳,等.基于脑电信号样本熵的急性脑梗死患者溶栓效果评价[J].中国医学物理学杂志,2022,39(1):81-86.[doi:DOI:10.3969/j.issn.1005-202X.2022.01.014]
　WANG Yaohui,L?Zhe,ZHANG Chongyang,et al.Evaluation of thrombolysis in patients with acute cerebral infarction based on EEG sample entropy[J].Chinese Journal of Medical Physics,2022,39(1):81-86.[doi:DOI:10.3969/j.issn.1005-202X.2022.01.014]
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基于脑电信号样本熵的急性脑梗死患者溶栓效果评价()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
39卷
期数:
2022年第1期
页码:
81-86
栏目:
医学信号处理与医学仪器
出版日期:
2022-01-17

文章信息/Info

Title:
Evaluation of thrombolysis in patients with acute cerebral infarction based on EEG sample entropy
文章编号:
1005-202X（2022）01-0081-06
作者:
王耀辉1; 吕喆1; 张重阳1; 梁振虎2
1.秦皇岛市第一医院急诊科， 河北 秦皇岛 066000； 2.燕山大学电气工程学院， 河北 秦皇岛 066000
Author(s):
WANG Yaohui1;  L?Zhe1;  ZHANG Chongyang1;  LIANG Zhenhu2
1. Department of Emergency, First Hospital of Qinhuangdao, Qinhuangdao 066000, China 2. Institute of Electrical Engineering, Yanshan University, Qinhuangdao 066000, China
关键词:
急性脑梗死; 血栓溶解疗法; 脑电图; 频谱; 样本熵
Keywords:
Keywords: acute cerebral infarction thrombolytic therapy electroencephalogram frequency spectrum sample entropy
分类号:
R318
DOI:
DOI:10.3969/j.issn.1005-202X.2022.01.014
文献标志码:
A
摘要:
目的：通过研究急性脑梗死患者溶栓治疗前后的脑电信号特征，探讨样本熵算法在急性脑梗死溶栓治疗监测中的应用。方法：采用频谱和样本熵分析76例急性脑梗死患者在溶栓前和溶栓治疗后24 h的EEG数据。分析溶栓治疗前后的变化规律。结果：溶栓治疗有效的患者，Delta与Alpha频段的能量在溶栓治疗前后差异具有统计学意义（P<0.05）；同时，溶栓前后，溶栓有效患者的Delta频段的样本熵在溶栓治疗前后的差异有统计学意义（P<0.001）。结论：Delta频段和Alpha频段的能量，以及样本熵可用于急性脑梗死溶栓治疗效果的监测评估。 【关键词】急性脑梗死；血栓溶解疗法；脑电图；频谱；样本熵
Abstract:
Abstract: Objective To explore the application of sample entropy algorithm in the monitoring of thrombolytic therapy for patients with acute cerebral infarction by studying the electroencephalogram (EEG) signal characteristics before and after thrombolytic therapy. Methods Frequency spectrum and sample entropy were used to analyze the EEG data of 76 patients with acute cerebral infarction before thrombolysis and 24 h after thrombolysis, and the changes before and after thrombolytic therapy were analyzed. Results In patients who responded to thrombolytic therapy, the energies of Delta and Alpha bands after thrombolytic therapy were significantly different from those before thrombolytic therapy (P<0.05), and the difference in the sample entropy of Delta band before and after thrombolytic therapy was also statistically significant (P<0.001). Conclusion The energies of Delta and Alpha bands as well as sample entropy can be used to monitor and evaluate the therapeutic effect of thrombolytic therapy for acute cerebral infarction.

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备注/Memo

备注/Memo:
【收稿日期】2021-08-20 【基金项目】河北省科技厅重点研发计划(172777202)；秦皇岛市科学技术研究与发展计划(201805A159) 【作者简介】王耀辉，硕士，主治医师，主要从事神经重症及心肺脑复苏的研究，E-mail: wangyaohui222@163.com 【通信作者】梁振虎，博士，教授，主要从事非线性理论及神经振荡理论在麻醉脑状态监测中的应用，脑电及脑氧信息联合的系统设计及在临床中的应用等研究工作，E-mail: zh@ysu.edu.cn
更新日期/Last Update: 2022-01-17