[1]杨卫周,张银刚,王莹,等.FePt/GO纳米复合材料制备方法及对胫骨骨折患者肢体功能的影响[J].中国医学物理学杂志,2021,38(4):501-504.[doi:DOI:10.3969/j.issn.1005-202X.2021.04.019]
　YANG Weizhou,ZHANG Yingang,WANG Ying,et al.Preparation of FePt/GO nanocomposite and its effect on limb function of tibial fracture patients[J].Chinese Journal of Medical Physics,2021,38(4):501-504.[doi:DOI:10.3969/j.issn.1005-202X.2021.04.019]
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FePt/GO纳米复合材料制备方法及对胫骨骨折患者肢体功能的影响()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
38卷
期数:
2021年第4期
页码:
501-504
栏目:
生物材料与力学
出版日期:
2021-04-29

文章信息/Info

Title:
Preparation of FePt/GO nanocomposite and its effect on limb function of tibial fracture patients
文章编号:
1005-202X（2021）04-0501-04
作者:
杨卫周; 张银刚; 王莹; 苏薇; 张波波; 边卫国; 李萌; 韩学哲
西安交通大学第一附属医院骨科， 陕西 西安 710061
Author(s):
YANG Weizhou;  ZHANG Yingang;  WANG Ying;  SU Wei;  ZHANG Bobo;  BIAN Weiguo;  LI Meng;  HAN Xuezhe
Department of Orthopaedics, First Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710061, China
关键词:
胫骨骨折; 化学还原法; FePt/GO纳米复合材料; 制备方法; 肢体功能; 膝关节活动度
Keywords:
Keywords: tibial fracturechemical reduction method FePt/GO nanocomposite preparation method limb function knee joint range of motion
分类号:
R318.08；R683.4
DOI:
DOI:10.3969/j.issn.1005-202X.2021.04.019
文献标志码:
A
摘要:
目的：探讨FePt/GO纳米复合材料制备方法及对胫骨骨折患者肢体功能的影响。方法：采用化学还原法制备FePt/GO纳米复合材料，并从材料的热性能、抗吸湿性能及力学性能等评估制备材料的理化性能。选择124例胫骨骨折患者为对象，随机数字表法分为两组，各62例。对照组采用切开复位内固定术治疗，观察组采用FePt/GO纳米复合材料干预，术后对患者进行6个月随访，比较两组肢体功能、膝关节活动度。结果：FePt/GO纳米复合材料在10°~20°之间出现宽峰为FePt材料的弥散峰；在6°~15°出现的宽峰为GO材料的弥散峰；FePt/GO纳米复合材料中随着GO浓度的升高，拉伸特性降低；PBA份数为10份时拉伸强度比纯样品拉伸强度46.73 MPa下降18%；而复合材料的弯曲特性随着GO含量增加而增加；观察组术后6个月疼痛、功能、活动度评分及TPA和PA度数均高于对照组（P<0.05）。结论：采用化学还原法成功制备FePt/GO纳米复合材料，且制备材料具有良好的理化性能，用于胫骨骨折患者有助于改善患者肢体功能及关节活动度，能为胫骨骨折治疗提供新的材料。
Abstract:
Abstract: Objective To investigate the method for the preparation of FePt/GO nanocomposite and to discuss its intervention effect on limb function of patients with tibial fracture. Methods FePt/GO nanocomposite was prepared by chemical reduction method, and its physical and chemical properties were evaluated from the aspects of thermal properties, moisture absorption resistance and mechanical properties. A total of 124 patients with tibial fracture were randomly divided into two groups, with 62 cases in each group. The patients in control group were treated with open reduction and internal fixation, while those in observation group were intervened with FePt/GO nanocomposite. The patients were followed-up for 6 months after operation, and the limb function and knee joint range of motion of two groups were compared. Results The wide peak of FePt/GO nanocomposite which occurred between 10° and 20°was the dispersion peak of FePt material, while the wide peak which occurred between 6° and 15°was the dispersion peak of GO material. The tensile property of FePt/GO nanocomposite was decreased with the increase of GO concentration and the tensile strength of the nanocoposite with 10 phr PBA was decreased by 18% compared with that of pure samples (46.73 MPa). However, the bending property of the composite was increased with the increase of GO content. The scores of pain, function and activity, tibial plateau angle and posterior slope angle in observation group at 6 months after operation were higher than those in control group (P<0.05). Conclusion FePt/GO nanocomposite is successfully prepared by chemical reduction method, and the prepared material which has good physical and chemical properties can be used in patients with tibial fracture for improving limb function and joint range of motion, and serves as a novel material for the treatment of tibial fracture.

相似文献/References:

[1]王芸,王枭冶,米雷,等.锁定接骨板外置治疗42A3型骨折的生物力学分析[J].中国医学物理学杂志,2023,40(7):909.[doi:DOI:10.3969/j.issn.1005-202X.2023.07.019]
　WANG Yun,WANG Xiaoye,et al.Biomechanical analysis of external locking plate in the treatment of type 42A3 fracture[J].Chinese Journal of Medical Physics,2023,40(4):909.[doi:DOI:10.3969/j.issn.1005-202X.2023.07.019]

备注/Memo

备注/Memo:
【收稿日期】2020-12-25 【基金项目】国家自然科学基金（81672187）；陕西省自然科学基金（2017JQ8022） 【作者简介】杨卫周，硕士，主治医师，E-mail: 3233925477@qq.com 【通信作者】韩学哲，博士，副主任医师，E-mail: a736950698@foxmail.com
更新日期/Last Update: 2021-04-29