[1]刘啸峰,黄述斌,胡磊.CT动态增强扫描中时间密度曲线及特征参数值对孤立性肺结节的诊断价值[J].中国医学物理学杂志,2021,38(6):713-716.[doi:DOI:10.3969/j.issn.1005-202X.2021.06.010]
　LIU Xiaofeng,HUANG Shubin,HU Lei.Diagnostic value of time-density curve and characteristic parameters in dynamic contrast-enhanced CT scan for solitary pulmonary nodules[J].Chinese Journal of Medical Physics,2021,38(6):713-716.[doi:DOI:10.3969/j.issn.1005-202X.2021.06.010]
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CT动态增强扫描中时间密度曲线及特征参数值对孤立性肺结节的诊断价值()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
38卷
期数:
2021年第6期
页码:
713-716
栏目:
医学影像物理
出版日期:
2021-06-29

文章信息/Info

Title:
Diagnostic value of time-density curve and characteristic parameters in dynamic contrast-enhanced CT scan for solitary pulmonary nodules
文章编号:
1005-202X（2021）06-0713-04
作者:
刘啸峰1; 黄述斌2; 胡磊1
1.池州市人民医院医学影像科， 安徽 池州 247000； 2.池州市人民医院病理科， 安徽 池州 247000
Author(s):
LIU Xiaofeng1;  HUANG Shubin2;  HU Lei1
1. Department of Medical Imaging, Chizhou Peoples Hospital, Chizhou 247000, China 2. Department of Pathology, Chizhou Peoples Hospital, Chizhou 247000, China
关键词:
孤立性肺结节; 计算机断层扫描术; 动态增强扫描; 时间密度曲线; 特征参数
Keywords:
Keywords: solitary pulmonary nodule computed tomography dynamic contrast-enhanced scan time-density curve characteristic parameter
分类号:
R816.4
DOI:
DOI:10.3969/j.issn.1005-202X.2021.06.010
文献标志码:
A
摘要:
目的：分析CT动态增强扫描中时间密度曲线及特征参数值对孤立性肺结节的诊断价值。方法：回顾性分析95例孤立性肺结节病变患者的临床资料，所有患者均行CT动态增强扫描检查及病理活检。依据病理结果，分析CT动态增强扫描的特异性、敏感性及准确性，并对不同类型孤立性肺结节时间密度曲线及特征参数值进行比较分析。结果：（1）95例孤立性肺结节病变患者中，恶性结节67例、良性结节14例，炎性结节14例；（2）CT动态增强扫描诊断孤立性肺结节病变性质的特异性为83.33%，敏感性为95.38%，准确性为91.58%；（3）恶性结节及炎症结节患者在CT动态增强扫描中各时间点的CT值均高于良性结节组（P<0.05）；在CT动态增强扫描300及480 s时，炎性结节组CT值较恶性结节组下降显著（P<0.05）；（4）恶性结节组及炎性结节组结节强化值（PH）、孤立性肺结节PH与主动脉PH之比均明显高于良性结节组（P<0.05）。结论：对孤立性肺结节病变患者行CT动态增强扫描，时间密度曲线及特征参数值可以为良、恶性孤立性肺结节提供一定的诊断依据。
Abstract:
Abstract: Objective To analyze the diagnostic value of time-density curve and characteristic parameters in dynamic contrast-enhanced computed tomography (CT) scan for solitary pulmonary nodules. Methods The clinical data of 95 patients with solitary pulmonary nodules were retrospectively analyzed. All patients underwent dynamic contrast-enhanced CT scan and pathological biopsy. According to the pathological results, the specificity, sensitivity and accuracy of dynamic contrast-enhanced CT scan in the diagnosis of solitary pulmonary nodules were analyzed. The time-density curves and characteristic parameters of different types of solitary pulmonary nodules were compared and analyzed. Results There were 67 malignant nodules, 14 benign nodules and 14 inflammatory nodules in 95 patients with solitary pulmonary nodules. The specificity, sensitivity and accuracy of dynamic contrast-enhanced CT in diagnosing solitary pulmonary nodules were 83.33%, 95.38% and 91.58%, respectively. The CT values of patients with malignant nodules and inflammatory nodules at each time point in dynamic contrast-enhanced CT scan were higher than those in benign nodules group (P<0.05). At 300 s and 480 s of dynamic contrast-enhanced CT scan, the CT value of inflammatory nodules group was significantly lower than that of malignant nodules group (P<0.05). The peak?eight (PH) and the ratio between PH of solitary pulmonary nodules and aortic PH (SPH/PPH) of malignant nodules group and inflammatory nodules group were significantly higher than those of benign nodules group (P<0.05). Conclusion The time-density curve and characteristic parameters in dynamic contrast-enhanced CT scan can provide certain diagnostic basis for benign and malignant solitary pulmonary nodules.

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备注/Memo

备注/Memo:
【收稿日期】2020-11-19 【基金项目】安徽省重点研究与开发计划（1804h08020238） 【作者简介】刘啸峰，副主任医师，研究方向：腹部疾病的影像诊断，E-mail: 694195589@qq.com
更新日期/Last Update: 2021-06-29