[1]刘凌湘,易兰,黄贤海,等.铅门固定技术在全段食管癌调强放疗计划设计中的应用[J].中国医学物理学杂志,2021,38(7):809-813.[doi:DOI:10.3969/j.issn.1005-202X.2021.07.004]
　LIU Lingxiang,YI Lan,HUANG Xianhai,et al.Application of fixed-jaw technique in intensity-modulated radiotherapy planning for esophageal cancer[J].Chinese Journal of Medical Physics,2021,38(7):809-813.[doi:DOI:10.3969/j.issn.1005-202X.2021.07.004]
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铅门固定技术在全段食管癌调强放疗计划设计中的应用()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
38卷
期数:
2021年第7期
页码:
809-813
栏目:
医学放射物理
出版日期:
2021-07-26

文章信息/Info

Title:
Application of fixed-jaw technique in intensity-modulated radiotherapy planning for esophageal cancer
文章编号:
1005-202X（2021）07-0809-05
作者:
刘凌湘; 易兰; 黄贤海; 陈照辉
广州市番禺区中心医院肿瘤科， 广东 广州 511400
Author(s):
LIU Lingxiang;  YI Lan;  HUANG Xianhai;  CHEN Zhaohui
Department of Oncology, Guangzhou Panyu Central Hospital, Guangzhou 511400, China
关键词:
食管癌; 铅门固定技术; 调强放疗; 剂量学
Keywords:
Keywords: esophageal cancer fixed-jaw technique intensity-modulated radiotherapy dosimetry
分类号:
R730.55；R811.1
DOI:
DOI:10.3969/j.issn.1005-202X.2021.07.004
文献标志码:
A
摘要:
目的：通过比较铅门固定技术与传统的铅门适形技术在全段食管癌调强放疗剂量学的差异，探讨铅门固定的射野优化方式在全段食管癌调强计划设计中的作用。方法：选取10例晚期全段食管癌患者，分别制定2个调强计划，F-plan计划为部分射野进行铅门固定设计，C-plan计划为所有射野铅门适形于靶区。比较两种计划靶区的剂量分布、适形度指数（CI）、均匀性指数（HI）和危及器官受量，同时记录总的机器跳数（MU）。结果：靶区剂量分布基本一致，除PCTV的适形度C-plan计划略优于F-plan计划，差异有统计学意义外（P<0.05），其它各参数无显著性差异。同时，C-plan计划的MU略低于F-plan计划，差异有统计学意义（P<0.05）。危及器官受量：除脊髓，两种计划的Dmax未见显著性差异外，双肺的MLD、V5、V10、V15、V20以及心脏受量的各参数，F-plan计划均优于C-plan计划，差异有统计学意义（P<0.05）。结论：对于全段食管癌调强计划，在满足靶区临床剂量学要求的前提下，铅门固定技术较传统的铅门适形技术能显著降低双肺和心脏的照射剂量，值得推广应用。
Abstract:
Abstract: Objective To compare the dosimetric differences between fixed-jaw technique and traditional jaw conformal technique in IMRT planning for esophageal cancer, and to explore the role of field optimization by fixed-jaw technique in IMRT planning for esophageal cancer.?ethods Two kinds of IMRT plans, namely F-plan in which fixed jaw was used for some of the fields and C-plan in which all the fields were designed to be conformal to the target area, were designed for 10 patients with advanced esophageal cancer. The dose distribution, conformity index, homogeneity index and doses delivered to organs-at-risk were compared between two kinds of plans, and the total monitor units were recorded at the same time.?esults The dose distribution in the target area was basically the same. Except that the conformity index of planning clinical target volume in C-plan was slightly better than that in F-plan, with statistical differences (P<0.05), there was no significant difference in other parameters. Meanwhile, the monitor units of C-plan was lower than that of F-plan, with statistical differences (P<0.05). The difference between two kinds of plans in the Dmax of spinal cord was trivial, but the mean dose, V5, V10, V15, V20 of lungs and the dosimetric parameters of the heart in F-plan were superior to those in C-plan, with statistical differences (P<0.05).?onclusion For the IMRT plan of esophageal cancer, on the premise of meeting the clinical dosimetric requirements, fixed-jaw technique can significantly reduce the dose delivered to both lungs and the heart compared with traditional jaw conformal technique, worthy of popularization and application.

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备注/Memo

备注/Memo:
【收稿日期】2021-01-18 【作者简介】刘凌湘，工程师，研究方向：放疗计划设计与放疗质控，E-mail: 740599037@qq.com
更新日期/Last Update: 2021-07-26