[1]陈斐,唐澍.磁共振弥散加权成像在鉴别肝脏局灶性良恶性病变中的诊断价值[J].中国医学物理学杂志,2020,37(7):894-897.[doi:DOI:10.3969/j.issn.1005-202X.2020.07.018]
　CHEN Fei,TANG Shu.Diagnostic value of diffusion-weighted magnetic resonance imaging in malignant and benign hepatic focal lesions[J].Chinese Journal of Medical Physics,2020,37(7):894-897.[doi:DOI:10.3969/j.issn.1005-202X.2020.07.018]
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磁共振弥散加权成像在鉴别肝脏局灶性良恶性病变中的诊断价值()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
37
期数:
2020年第7期
页码:
894-897
栏目:
医学影像物理
出版日期:
2020-07-25

文章信息/Info

Title:
Diagnostic value of diffusion-weighted magnetic resonance imaging in malignant and benign hepatic focal lesions
文章编号:
1005-202X（2020）07-0894-04
作者:
陈斐1; 唐澍2
1.郴州市第一人民医院放射科， 湖南 郴州 423000； 2郴州市第一人民医院南院肿瘤内科， 湖南 郴州 423000
Author(s):
CHEN Fei1;  TANG Shu2
1. Department of Radiology, Chenzhou No.1 Peoples Hospital, Chenzhou 423000, China 2. Department of Medical Oncology, the South Branch of Chenzhou No.1 Peoples Hospital, Chenzhou 423000, China
关键词:
肝脏局灶性病变; 磁共振; 弥散加权成像; 表观弥散系数
Keywords:
Keywords: hepatic focal lesions magnetic resonance diffusion-weighted imaging apparent diffusion coefficient
分类号:
R735.7
DOI:
DOI:10.3969/j.issn.1005-202X.2020.07.018
文献标志码:
A
Abstract:
Abstract: Objective To investigate the value of diffusion-weighted magnetic resonance imaging (DWI) in the differential diagnosis of malignant and benign hepatic focal lesions. Methods All the enrolled 83 patients with hepatic focal lesions were examined by conventional MRI and DWI. After selecting the regions of interest in DWI, the apparent diffusion coefficients (ADC value) under different diffusion sensitivity coefficients (b value) were determined, and the DWI signal characteristics of patients with hepatic focal lesions were analyzed. The ADC values of patients with benign and malignant lesions were compared under different b values. The results of the differential diagnosis by conventional MRI and DWI were then compared with pathological results for evaluating the diagnostic efficiency. Results There were 57 cases of malignant lesions, including 22 cases of liver metastasis and 35 cases of primary liver cancer, and 26 of benign lesions, including 12 cases of liver cyst and 14 cases of liver hemangioma. On DWI, primary liver cancer was manifested as high or mixed signals and liver metastasis and liver hemangioma had high signals and the signal of liver cyst was hypointense. Under high, middle, low b values, the ADC values of malignant hepatic focal lesions were lower than those of benign hepatic focal lesions (P<0.05). The specificity and accuracy of DWI in the diagnosis of malignant hepatic focal lesions were higher than those of conventional MRI (96.15% vs 69.23%, 90.36% vs 72.29% P<0.05), and the misdiagnosis rate was lower than that of conventional MRI (3.85% vs 30.77%, P<0.05). There was no significant difference in the sensitivity and the rate of missed diagnosis between two methods in the diagnosis of malignant hepatic focal lesions (87.72% vs 73.68%, 12.28% vs 26.32% P>0.05). Conclusion In the differential diagnosis of malignant and benign hepatic focal lesions by MRI, DWI can effectively improve the diagnostic specificity and accuracy for malignant hepatic focal lesions by comparing the DWI image signal characteristics and ADC values of patients with malignant and benign hepatic focal lesions.

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备注/Memo

备注/Memo:
【收稿日期】2020-03-04 【作者简介】陈斐，主治医师，E-mail: af540029cf@qq.com 【通信作者】唐澍，主治医师，E-mail: zy883926@qq.com
更新日期/Last Update: 2020-07-28