[1]田秀梅,申正文,董文玲,等.湿纱布与bolus在腱鞘巨细胞瘤放疗中的剂量学差异[J].中国医学物理学杂志,2020,37(6):680-684.[doi:DOI:10.3969/j.issn.1005-202X.2020.06.005]
　TIAN Xiumei,SHEN Zhengwen,DONG Wenling,et al.Dosimetric differences in radiotherapy using wet gauze versus bolus for giant cell tumor of tendon sheath[J].Chinese Journal of Medical Physics,2020,37(6):680-684.[doi:DOI:10.3969/j.issn.1005-202X.2020.06.005]
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湿纱布与bolus在腱鞘巨细胞瘤放疗中的剂量学差异()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
37
期数:
2020年第6期
页码:
680-684
栏目:
医学放射物理
出版日期:
2020-06-25

文章信息/Info

Title:
Dosimetric differences in radiotherapy using wet gauze versus bolus for giant cell tumor of tendon sheath
文章编号:
1005-202X（2020）06-0680-05
作者:
田秀梅1; 申正文1; 董文玲1; 靳富1; 吴府容1; 夏徐2
1.重庆大学附属肿瘤医院/重庆市肿瘤研究所/重庆市肿瘤医院肿瘤放射治疗中心， 重庆 400030； 2.重庆市垫江县中医院肿瘤血液科， 重庆 408300
Author(s):
TIAN Xiumei1;  SHEN Zhengwen1;  DONG Wenling1;  JIN Fu1;  WU Furong1;  XIA Xu 2
1. Department of Radiation Oncology, Chongqing University Cancer Hospital/Chongqing Cancer Institute/Chongqing Cancer Hospital, Chongqing 400030, China 2. Department of Oncology and Hematology, Traditional Chinese Medicine Hospital of Dianjiang County, Chongqing 408300, China
关键词:
腱鞘巨细胞瘤; 湿纱布; bolus; 剂量学
Keywords:
Keywords: giant cell tumor of tendon sheath wet gauze bolus dosimetry
分类号:
R312；R811.1
DOI:
DOI:10.3969/j.issn.1005-202X.2020.06.005
文献标志码:
A
摘要:
目的：探讨利用湿纱布与bolus在腱鞘巨细胞瘤放疗中的剂量学差异。方法：回顾性选取8例采用湿纱布作为组织等效补偿膜的腱鞘巨细胞瘤患者，以原始CT扫描序列作为第一组数据，勾画实际body（不包括纱布），然后，添加虚拟bolus，获得第二套数据。分别在Varian Eclipse 13.6制作两组计划（Plan_gauze和Plan_bolus），比较两组数据的剂量学差异。最后，采用两组模体，分别实测两种组织补偿物对射线的衰减程度，比较Plan_gauze和Plan_bolus的差异。结果：Plan_gauze组与Plan_bolus组的均匀性指数、适形度指数、Dmax、Dmean、总机器跳数以及低剂量区域体积（V10、V20）和高剂量区域体积（V80、V90）的比较均无统计学差异（P>0.05），两组计划靶区剂量均能满足临床要求，且两组模体中，Plan_gauze和Plan_bolus实测剂量值差异较小。结论：使用湿纱布作为组织补偿物在腱鞘巨细胞瘤放疗中能达到虚拟bolus的剂量分布。考虑腱鞘巨细胞瘤的特殊性，使用湿纱布能够更好地包覆靶区，减小组织补偿下空腔，结果更加准确，可推荐作为该肿瘤的补偿物。
Abstract:
Abstract: Objective To investigate the dosimetric differences in the radiotherapy using wet gauze or bolus as tissue equivalent compensation for giant cell tumor of tendon sheath. Methods Eight patients with giant cell tumor of tendon sheath using wet gauze as tissue equivalent compensation were selected retrospectively. The original CT scan sequence was used as the first set of data, and the actual body (excluding gauze) was drawn manually. Then the virtual bolus was taken as tissue equivalent compensation to obtain the second set of data. Two groups of plans (Plan_gauze and Plan_bolus) were calculated in Varian Eclipse 13.6 to compare the dosimetric differences between two groups. Finally, two groups of phantoms were applied to measure the attenuation of the two kinds of tissue compensators to rays, and the differences between Plan_gauze and Plan_bolus were compared. Results No statistical difference was found between Plan_gauze and Plan_bolus in homogeneity index, conformity index, Dmax, Dmean, total monitor units, low dose area volume (V10, V20) and high dose area volume (V80, V90) (all P>0.05). Both groups met clinical requirements, and the experiments on two groups of phantoms showed that the differences in measured dose between Plan_gauze and Plan_bolus were trivial. Conclusion Similar dose distribution can be achieved by using wet gauze or virtual bolus as tissue compensation in the radiotherapy for giant cell tumor of tendon sheath. Considering the particularity of giant cell tumor of tendon sheath, wet gauze can be recommended as a tissue equivalent compensation for it can better cover the target area and reduce the cavity under tissue compensation, obtaining more accurate results.

备注/Memo

备注/Memo:
【收稿日期】2020-01-07 【基金项目】重庆市科卫联合医学科研项目（2019MSXM040） 【作者简介】田秀梅，硕士，助理工程师，研究方向：放射物理技术，E-mail: txm805988970@126.com 【通信作者】吴府容，硕士，主治医师，研究方向：肿瘤放射治疗学，E-mail: wfr10551664@126.com
更新日期/Last Update: 2020-07-03