短T2组织磁共振成像技术研究进展-《中国医学物理学杂志》

文章信息/Info

作者:: 雷格格1; 2; 张光锋1; 贾慧惠3; 吴继志3; 常严2; 易佩伟4; 盛茂3; 杨晓冬2; 1. 南京理工大学电子工程与光电技术学院，江苏南京210094；2. 中国科学院苏州生物医学工程技术研究所，江苏苏州215163； 3. 苏州大学附属儿童医院放射科，江苏苏州215025；4. 南方医科大学生物医学工程学院，广东广州510515

Author(s):: LEI Gege1; 2; ZHANG Guangfeng1; JIA Huihui3; WU Jizhi3; CHANG Yan2; YI Peiwei4; SHENG Mao3; YANG Xiaodong2; 1.School of Electronic and Optical Engineering, Nanjing University of Science and Technology, Nanjing 210094, China 2. Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou 215163, China 3. Department of Radiology, Childrens Hospital of Soochow University, Suzhou 215025, China 4. School of Biomedical Engineering, Southern Medical University, Guangzhou 510515, China

Keywords:: short T2 tissues quantitative magnetic imaging pulse sequence contrast enhancement review

摘要:: 常规磁共振有较好的软组织对比度，但对骨、关节、软骨、肌腱等短T2组织（约小于10 ms）的分辨能力欠佳。可通过增强短T2组织的图像对比度（利用魔角效应和注射造影剂）、开发专用的短T2组织成像技术（可变回波时间成像、超短回波时间成像和零回波时间成像）和抑制周围长T2组织来获得较高质量的短T2组织图像。近年来，定量磁共振成像技术因其能精准地反映与病变相关的生化参数特征也被应用于短T2组织病变的临床诊断。本研究主要从增强短T2组织对比度、缩短序列回波时间和长T2组织抑制等3个方面回顾了短T2组织磁共振成像的常规方法，并对短T2组织的定量磁共振成像技术进行了系统的分析和展望。

Abstract:: The conventional magnetic resonance imaging (MRI) has a high soft tissue contrast but a poor ability to distinguish short T2 tissues (<10 ms) such as bone, joint, cartilage and tendon. The high-quality images of the short T2 tissues can be obtained by enhancing the image contrast of short T2 tissue (using magic angle effect or injecting contrast agent), developing special short T2 tissue imaging technologies (variable echo time imaging, ultrashort echo time imaging and zero echo time imaging) and suppressing the surrounding long T2 tissues. In recent years, quantitative magnetic resonance imaging technology has been applied to the clinical diagnosis of short T2 tissue lesions because it can accurately reflect the characteristics of biochemical parameters related to the lesions. Herein the conventional magnetic resonance imaging of short T2 tissues is reviewed from 3 aspects, namely enhancing short T2 tissue contrast, shortening the echo time of sequence and suppressing long T2 tissues. Furthermore, the quantitative magnetic resonance imaging of short T2 tissues is systematically analyzed and its prospects are discussed.