[1]汪金龙,屈卫卫,谢树青,等. 扫描治疗头的蒙特卡罗模型研究[J].中国医学物理学杂志,2019,36(9):1001-1007.[doi:DOI:10.3969/j.issn.1005-202X.2019.09.002]
　WANG Jinlong,QU Weiwei,XIE Shuqing,et al. Investigation of a Monte Carlo model of scanning nozzle[J].Chinese Journal of Medical Physics,2019,36(9):1001-1007.[doi:DOI:10.3969/j.issn.1005-202X.2019.09.002]
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 扫描治疗头的蒙特卡罗模型研究()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
36卷
期数:
2019年第9期
页码:
1001-1007
栏目:
医学放射物理
出版日期:
2019-09-25

文章信息/Info

Title:
 Investigation of a Monte Carlo model of scanning nozzle
文章编号:
1005-202X（2019）09-1001-07
作者:
 汪金龙1; 屈卫卫2; 谢树青1; 王宏凯3; 袁晓刚1
 1.广州泰和肿瘤医院质子技术部， 广东 广州 510555； 2.苏州大学医学部放射医学与防护学院， 江苏 苏州 215123； 3.生态环境部核与辐射安全中心， 北京 102400
Author(s):
 WANG Jinlong1;  QU Weiwei2;  XIE Shuqing1;  WANG Hongkai3;  YUAN Xiaogang1
 1. Proton Technology Department, Guangzhou Concord Cancer Center, Guangzhou 510555, China; 2. School of Radiation Medicine and Protection, Medical College of Soochow University, Suzhou 215123, China; 3. Nuclear and Radiation Safety Center, Ministry of Ecology and Environment, Beijing 102400, China
关键词:
 ; 扫描治疗头; 质子治疗; 蒙特卡罗模拟
Keywords:
 ; Keywords: scanning nozzle;  proton therapy;  Monte Carlo simulation
分类号:
R312；R811.1
DOI:
DOI:10.3969/j.issn.1005-202X.2019.09.002
文献标志码:
A
摘要:
 【摘要】目的：评估质子治疗中扫描治疗头对束流品质的影响。方法：通过扫描治疗头的蒙特卡罗模型研究深度剂量曲线的变化，计算射程移位器对束斑截面的影响以及分析扫描磁场对单质子束的偏转情况。结果：随着能量的增加，质子在水中的射程增加，同时散射也越严重，最终布拉格峰变宽，尾端变胖。相比于直接入射水模，通过治疗头后质子在水中的射程缩短了约0.6 cm，但布拉格峰形基本保持不变；将4 cm厚度聚乙烯射程移位器放置于距离水模表面0、10、20、30、40和50 cm分别进行独立计算，发现与水模距离越远，质子的散射越大，因此治疗过程中射程移位器应尽量靠近患者；当扫描磁铁加载磁场后，束斑将偏离束流中心。设置纵向扫描磁场Bx=0.1 T，横向扫描磁场By=0.3 T，180 MeV质子束在Y方向偏离了2.693 cm，横向扫描磁场使质子在-X方向上偏离了8.427 cm。当束流有偏转的时候，要求射程移位器横截面足够大以满足宽扫描场的需要。结论：扫描治疗头的蒙特卡罗模型将有助于理解质子治疗这一新兴的放疗方法以及熟悉扫描治疗的束流特性，在调试和质量保证中提供参考。
Abstract:
Abstract: Objective To estimate the effects of scanning nozzle in proton therapy on beam quality. Methods A Monte Carlo model of scanning nozzle was established to investigate the variation of depth dose curve, calculate the effect of range shifter on the cross section of beam spot and analyze the deflection of single proton beam caused by scanning magnet field. Results With the increase of energy, the range of proton in water was increased, and meanwhile scattering was more serious. Finally, the Bragg peak became wider and the tail became fatter. Compared with the direct incident into water phantom, the range of proton passing through the scanning nozzle in water was shortened by about 0.6 cm, but the Bragg peak shape remained basically unchanged. The range shifter of 4 cm thick polyethylene was placed at 0, 10, 20, 30, 40 and 50 cm away from the water phantom surface for independent calculation, and it was found that the farther the distance from the water phantom was, the greater the proton scattering was. Therefore, the range shifter should be as close as possible to the patient during treatment. The beam spot deviated from beam center due to the magnetic field loaded by scanning magnet. With the longitudinal magnetic field Bx = 0.1 T and transverse magnetic field By=0.3 T, 180 MeV proton beam had a deviation of 2.693 cm in Y direction and 8.427 cm in -X direction. When the beam was deflected, the cross section of range shifter was required to be wide enough to satisfy the need of wide scan field. Conclusion The Monte Carlo model of scanning nozzle is helpful for understanding proton therapy as an emerging radiotherapy method and the beam characteristics of scanning therapy and providing good references in commissioning and quality assurance.

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备注/Memo

备注/Memo:
 【收稿日期】2019-03-12
【基金项目】国家自然科学青年基金（11705123）
【作者简介】汪金龙，注册核安全工程师，研究方向：质子治疗、医学影像、辐射防护等，E-mail: jinlong.wang@ccm.cn
更新日期/Last Update: 2019-09-23