[1]许磊,康亚宁,马静,等.压迫式弹性成像与声脉冲辐射力成像技术在乳腺肿瘤良恶性鉴别中的价值比较[J].中国医学物理学杂志,2020,37(3):299-302.[doi:DOI:10.3969/j.issn.1005-202X.2020.03.008]
　XU Lei,KANG Yaning,MA Jing,et al.Compression elastography and acoustic radiation force imaging in differentiating benign and malignant breast tumors[J].Chinese Journal of Medical Physics,2020,37(3):299-302.[doi:DOI:10.3969/j.issn.1005-202X.2020.03.008]
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压迫式弹性成像与声脉冲辐射力成像技术在乳腺肿瘤良恶性鉴别中的价值比较()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
37
期数:
2020年第3期
页码:
299-302
栏目:
医学影像物理
出版日期:
2020-03-25

文章信息/Info

Title:
Compression elastography and acoustic radiation force imaging in differentiating benign and malignant breast tumors
文章编号:
1005-202X（2020）03-0299-04
作者:
许磊; 康亚宁; 马静; 杨媛媛; 赵俊; 王荣荣
西安市中医医院功能科， 陕西 西安 710021
Author(s):
XU Lei;  KANG Ya’ning;  MA Jing;  YANG Yuanyuan;  ZHAO Jun;  WANG Rongrong
Department of Function, Xi’an Hospital of Traditional Chinese Medicine, Xi’an 710021, China
关键词:
压迫式弹性成像; 声脉冲辐射力成像; 乳腺肿瘤; 良性肿瘤; 恶性肿瘤; 鉴别诊断
Keywords:
Keywords: compression elastography;  acoustic radiation force imaging;  breast tumor;  benign tumor;  malignant tumor;  differential diagnosis
分类号:
R737.9；R445.1
DOI:
DOI:10.3969/j.issn.1005-202X.2020.03.008
文献标志码:
A
摘要:
目的：探讨分析压迫式弹性成像（CE）与声脉冲辐射力成像（ARFI）技术在乳腺肿瘤良恶性鉴别中的价值。方法：选择门诊或住院行超声检查发现的有乳腺肿块患者71例共89个病灶，经病理组织学确认良性病灶57个，恶性病灶32个。对各病灶进行彩色多普勒超声检查，并采取CE及ARFI技术，分别计算病灶弹性应变率比值（SR）及声触诊组织定量（VTQ）值，采用ROC曲线分析SR、VTQ对良恶性肿瘤的诊断效能。结果：恶性组病灶VTQ值与SR值均显著高于良性组（P<0.05）。采用ROC曲线分析VTQ、SR对乳腺良恶性肿瘤诊断效能，VTQ诊断曲线下面积（AUC）为0.918，95% CI为0.871~0.980（P<0.05），最佳截断值为3.97，在此最佳截断值下，VTQ诊断敏感性94.64%、诊断特异性90.63%；SR诊断AUC为0.899，95% CI为0.854~0.956（P<0.05），最佳截断值为4.12，在此最佳截断值下，SR诊断敏感性92.86%、诊断特异性84.38%。VTQ和SR诊断敏感性、特异性比较差异无统计学意义（P>0.05）。结论：两种超声诊断技术对乳腺良恶性肿瘤均具有较高的诊断价值，其诊断效能相似，临床上可联合使用，以实现优势互补，提高对乳腺癌的早期检出率。
Abstract:
Abstract: Objective To investigate the value of compression elastography (CE) and acoustic radiation force imaging (ARFI) in the differential diagnosis of benign and malignant breast tumors. Methods A total of 71 patients with breast tumors detected by ultrasonography were enrolled, including 89 lesions. The histopathologic examination showed that there were 57 benign lesions and 32 malignant lesions. The lesions were examined by color Doppler ultrasonography, and the elastic strain rate ratio (SR) and virtual touch tissues quantification (VTQ) were calculated by CE and ARFI, separately. The diagnostic efficacy of SR and VTQ in benign and malignant breast tumors was analyzed by receiver operating characteristic (ROC) curve. Results The VTQ and SR in malignant group were significantly higher than those in benign group (P<0.05). The diagnostic efficiency of VTQ and SR in benign and malignant breast tumors was analyzed by ROC curve. The area under VTQ diagnostic curve was 0.918, with a 95% CI of 0.871-0.980 (P<0.05), and the best cut-off value was 3.97. At the best cut-off value, the diagnostic sensitivity and specificity of VTQ were 94.64% and 90.63%, respectively. The area under SR diagnostic curve was 0.899, with a 95% CI of 0.854-0.956 (P<0.05), and the best cut-off value was 4.12. The diagnostic sensitivity and specificity of SR at the best cut-off value were 92.86% and 84.38%, respectively. There was no significant difference in diagnostic sensitivity and specificity between VTQ and SR (P>0.05). Conclusion Both CE and ARFI have high diagnostic value for benign and malignant breast tumors, with similar diagnostic efficacy. The two ultrasound diagnostic techniques can be combined in clinic to achieve complementary advantages and further improve the early detection rate of breast cancer.

备注/Memo

备注/Memo:
【收稿日期】2019-10-13 【基金项目】陕西科技厅社会发展项目（2018SF-271） 【作者简介】许磊，硕士，主治医师，研究方向：浅表器官及肌骨疾病超声诊断，E-mail: zhshxm923@sina.com
更新日期/Last Update: 2020-04-02