[1]王晓春,王守宇,霍晓庆,等.热塑膜固定底板对IMRT计划三维剂量验证通过率的影响与修正[J].中国医学物理学杂志,2020,37(3):273-276.[doi:DOI:10.3969/j.issn.1005-202X.2020.03.003]
　WANG Xiaochun,WANG Shouyu,HUO Xiaoqing,et al.Effect of immobilization baseplate of thermoplastic film on the passing rate of IMRT 3D dosimetric verification and dose modification[J].Chinese Journal of Medical Physics,2020,37(3):273-276.[doi:DOI:10.3969/j.issn.1005-202X.2020.03.003]
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热塑膜固定底板对IMRT计划三维剂量验证通过率的影响与修正()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
37
期数:
2020年第3期
页码:
273-276
栏目:
医学放射物理
出版日期:
2020-03-25

文章信息/Info

Title:
Effect of immobilization baseplate of thermoplastic film on the passing rate of IMRT 3D dosimetric verification and dose modification
文章编号:
1005-202X（2020）03-0273-04
作者:
王晓春; 王守宇; 霍晓庆; 张清琴; 洪振宇; 路平; 吴鹏; 刘波; 王颖拓; 苗战会
新乡医学院第一附属医院放疗中心， 河南 卫辉 453100
Author(s):
WANG Xiaochun;  WANG Shouyu;  HUO Xiaoqing;  ZHANG Qingqin;  HONG Zhenyu;  LU Ping;  WU Peng;  LIU Bo;  WANG Yingtuo;  MIAO Zhanhui
Radiation Therapy Center, the First Affiliated Hospital of Xinxiang Medical University, Weihui 453100, China
关键词:
热塑膜固定底板; 调强放射治疗; 剂量修正; γ通过率
Keywords:
Keywords: immobilization baseplate of thermoplastic film;  intensity-modulated radiotherapy;  dose modification;  gamma passing rate
分类号:
R312；R811.1
DOI:
DOI:10.3969/j.issn.1005-202X.2020.03.003
文献标志码:
A
摘要:
目的：分析和评估一款热塑膜固定底板对调强放射治疗（IMRT）计划三维剂量验证通过率的影响，并对其进行剂量修正。方法：利用Octavius 4D三维剂量验证系统，对60例IMRT计划按照后入射野数占总射野数比值分成6组，分别进行仅有床板和有床板与热塑膜固定底板组合的三维剂量验证，以评估热塑膜固定底板对IMRT三维剂量验证通过率的影响。然后对入射野数占比最大的第6组进行剂量修正，并与修正前的γ通过率进行比较，评估剂量修正的作用。结果：未考虑固定底板时，6组IMRT计划γ通过率分别为：98.00%、96.87%、96.76%、94.82%、95.51%、95.32%；考虑固定底板以后分别为：98.88%、96.46%、95.85%、93.12%、93.22%、89.07%，考虑前后P值分别为0.147、0.534、0.406、0.051、0.030（t=2.566）、0.000（t=5.637），第5组和第6组有统计学差异。对第6组进行固定底板剂量修正以后，γ通过率平均为94.90%，提高5.8%。结论：热塑膜固定底板对IMRT计划三维剂量验证通过率有一定的影响，且当IMRT计划的后入射野数所占总射野数比值越大，影响越大，临床制定计划时有必要对固定底板进行剂量修正。
Abstract:
Abstract: Objective To analyze and evaluate the effect of an immobilization baseplate of thermoplastic film on the passing rate of intensity-modulated radiotherapy (IMRT) three-dimensional (3D) dosimetric verification, and to modify the dose. Methods Octavius 4D dosimetric verification system was used for 3D dosimetric verification. According to the proportion of the number of incident fields to the total number of fields, 60 cases of IMRT plans were divided into 6 group for the 3D dosimetric verification with couch plate alone or couch plate combined with immobilization baseplate of thermoplastic film so as to evaluate the effect of immobilization baseplate of thermoplastic film on the passing rate of IMRT 3D dosimetric verification. Dose modification was carried out in the 6th group which had the highest proportion of the number of incidence fields in all groups, and then the passing rate was compared with that before dose modification for evaluating the role of dose modification. Results Without considering immobilization baseplate, the gamma passing rates of 6 groups of IMRT plans were 98.00%, 96.87%, 96.76%, 94.82%, 95.51% and 95.32%, respectively; and after that immobilization baseplate was considered, the gamma passing rates were 98.88%, 96.46%, 95.85%, 93.12%, 93.22% and 89.07%, respectively. The corresponding P values were 0.147, 0.534, 0.406, 0.051, 0.030 (t=2.566) and 0.000 (t=5.637), respectively, and statistical differences were only found in the 5th and 6th groups. After the dose modification for immobilization baseplate in the 6th group, the average gamma passing was 94.90%, increased by 5.8%. Conclusion Immobilization baseplate of thermoplastic film has a certain effect on the passing rate of IMRT 3D dosimetric verification, and the larger proportion of the number of incident fields in IMRT plan is, the greater effect is. It is necessary to modify the dose of immobilization baseplate when making clinical plans.

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备注/Memo

备注/Memo:
【收稿日期】2019-10-22 【基金项目】河南省放射性损伤转化医学国际联合实验室项目（豫科外【2017】21号）；河南省科技发展计划；新乡医学院高原学科（豫科【2015】114号） 【作者简介】王晓春，硕士，放射技师，研究方向：医学物理，E-mail: 294299512@qq.com 【通信作者】苗战会，主任医师，研究生导师，研究方向：肿瘤综合治疗，E-mail: miaozhanhui@sina.com
更新日期/Last Update: 2020-04-02