[1]卢子红,杜乙,杨敬贤,等. 两种固定方式下颈部肿瘤首次放射治疗颈椎配准比较[J].中国医学物理学杂志,2019,36(6):632-635.[doi:DOI:10.3969/j.issn.1005-202X.2019.06.003]
　LU Zihong,DU Yi,YANG Jingxian,et al. Comparison of registration of cervical vertebra in the first radiotherapy using two different fixation methods for neck tumor[J].Chinese Journal of Medical Physics,2019,36(6):632-635.[doi:DOI:10.3969/j.issn.1005-202X.2019.06.003]
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 两种固定方式下颈部肿瘤首次放射治疗颈椎配准比较()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
36卷
期数:
2019年第6期
页码:
632-635
栏目:
医学放射物理
出版日期:
2019-06-25

文章信息/Info

Title:
 Comparison of registration of cervical vertebra in the first radiotherapy using two different fixation methods for neck tumor
文章编号:
1005-202X（2019）06-0632-04
作者:
 卢子红1; 杜乙1; 杨敬贤1; 李俊禹1; 于松茂1; 李廷廷2; 吴昊1
 1.北京大学肿瘤医院暨北京市肿瘤防治研究所放疗科/恶性肿瘤发病机制及转化研究教育部重点实验室， 北京 100142； 2.中国人民解放军第302医院， 北京 100039
Author(s):
 LU Zihong1;  DU Yi 1;  YANG Jingxian1;  LI Junyu1;  YU Songmao1;  LI Tingting2;  WU Hao1
 1. Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Radiation Oncology, Peking University Cancer Hospital & Institute, Beijing 100142, China; 2. 302 Military Hospital of PLA, Beijing 100039, China
关键词:
 ; 颈部肿瘤; 固定方式;  颈椎; 放射治疗
Keywords:
 ; Keywords: neck tumor;  fixation method;  cervical vertebra;  radiotherapy
分类号:
R739.91；R815.2
DOI:
DOI:10.3969/j.issn.1005-202X.2019.06.003
文献标志码:
A
摘要:
 【摘要】目的：在两种固定方式下，比较颈部肿瘤首次放射治疗颈椎的配准，以得到更为精准的固定方式，提高摆位和治疗精度速度，缩短治疗时间。方法：随机选取两种不同固定方式的颈部肿瘤患者各15例，分为A、B两组，分别测量首次放射治疗的CBCT图像和定位CT图像中7个颈椎椎体后缘到头枕底部的距离，比较CBCT图像和CT图像中距离的差值。采集两组患者所有距离配对差值进行对比分析。结果：A组固定方式颈椎配对差值分别C1=（-0.188 00±0.367 06）、C2=（-0.169 33±0.402 64）、C3=（-0.226 67±0.417 52）、C4=（-0.234 00±0.455 55）、C5=（-0.209 33±0.434 17）、C6=（-0.174 67±0.431 56）、C7=（-0.166 67±0.360 92） cm；B组固定方式颈椎配对差值分别为C1=（-0.112 00±0.199 61）、C2=（-0.044 00±0.157 92）、C3=（-0.038 67±0.218 86）、C4=（0.086 70±0.190 30）、C5=（-0.020 67±0.218 65）、C6=（0.129 33±0.463 33）、C7=（0.084 00±0.261 28） cm。两组固定方式中，两组数据配对差值均小于0.3 cm，均在临床治疗要求的摆位误差范围内，但B组配对差值明显小于A组。结论：与A组固定方式相比，B组固定方式更能提高颈椎的配准，保护脊髓等重要危及器官，从而进一步提高靶区照射的精确性，保证靶区的照射剂量，减少正常组织的受照剂量。
Abstract:
 Abstract: Objective To compare the registration of cervical vertebra in the first radiotherapy using two different fixation methods for neck tumors, so as to select a more optimal fixation method, improve the accuracy of positioning and treatment, and shorten the treatment time. Methods Thirsty patients with neck tumors were randomly divided into group A (n=15) and group B (n=15). The patients in two groups were treated with different fixation methods. The distance between the posterior edge of 7 cervical vertebrae and the base of the head and occipital was measured in the CBCT images of the first radiotherapy and the localization CT images, and the distance difference between CBCT images and CT images was compared. Finally, the registration differences between two groups were compared and analyzed. Results The registration differences in group A were as follows: C1=(-0.188 00±0.367 06), C2=(-0.169 33±0.402 64), C3=(-0.226 67±0.417 52), C4=(-0.234 00±0.455 55), C5=(-0.209 33±0.434 17), C6=(-0.174 67±0.431 56), C7=(-0.166 67±0.360 92) cm. The registration differences in group B were as follows: C1=(0.112 00±0.199 61), C2=(0.044 00±0.157 92), C3=(0.038 67±0.218 86), C4=(0.086 70±0.190 30), C5=(-0.020 67±0.218 65), C6=(0.129 33±0.463 33), C7=(0.084 00±0.261 28) cm. All the registration differences in the two groups were less than 0.3 cm, within the range of clinical requirements, but the registration differences in group B were significantly lower than those in group A. Conclusion Compared with the fixation method in group A, the fixation method in group B can improve the registration of cervical vertebra and protect the spinal cord and other organs-at-risk, thereby further improving the accuracy of target irradiation, ensuring the irradiation dose of target areas, and reducing the irradiation dose of normal tissues.

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备注/Memo

备注/Memo:
 【收稿日期】2019-03-10
【基金项目】北京市自然科学基金（1184014）；中国博士后科学基金（2017M620542）
【作者简介】卢子红，技师，研究方向：放射治疗技术，E-mail: 154846248@qq.com
【通信作者】吴昊，高级工程师，研究方向：医学物理，E-mail: 13552661030@139.com
更新日期/Last Update: 2019-06-25