[1]陈姗姗,高浪浪,刘海涛,等. 3D动脉自旋标记技术在1级高血压脑灌注中的应用价值[J].中国医学物理学杂志,2019,36(9):1049-1054.[doi:DOI:10.3969/j.issn.1005-202X.2019.09.011]
　CHEN Shanshan,GAO Langlang,LIU Haitao,et al. Application value of three-dimensional arterial spin labeling technique in grade 1 hypertensive cerebral perfusion[J].Chinese Journal of Medical Physics,2019,36(9):1049-1054.[doi:DOI:10.3969/j.issn.1005-202X.2019.09.011]
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 3D动脉自旋标记技术在1级高血压脑灌注中的应用价值()
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《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
36卷
期数:
2019年第9期
页码:
1049-1054
栏目:
医学影像物理
出版日期:
2019-09-25

文章信息/Info

Title:
 Application value of three-dimensional arterial spin labeling technique in grade 1 hypertensive cerebral perfusion
文章编号:
1005-202X（2019）09-1049-06
作者:
 陈姗姗1; 高浪浪2; 刘海涛3; 杜芳4; 侯炜寰2; 赵海涛2; 魏梦绮2
 1.空军军医大学第一附属医院超声科， 陕西 西安 710032； 2.空军军医大学第一附属医院放射科， 陕西 西安 710032； 3.空军军医大学第一附属医院心脏内科， 陕西 西安 710032； 4.空军军医大学第一附属医院神经内科， 陕西 西安 710032
Author(s):
 CHEN Shanshan1;  GAO Langlang2;  LIU Haitao3;  DU Fang4;  HOU Weihuan2;  ZHAO Haitao2;  WEI Mengqi2
 1. Department of Ultrasonography, the First Affiliated Hospital of Air Force Military Medical University, Xi’an 710032, China; 2. Department of Radiology, the First Affiliated Hospital of Air Force Military Medical University, Xi’an 710032, China; 3. Department of Cardiology, the First Affiliated Hospital of Air Force Military Medical University, Xi’an 710032, China; 4. Department of Neurology, the First Affiliated Hospital of Air Force Military Medical University, Xi’an 710032, China
关键词:
 ; 3D动脉自旋标记灌注成像; 高血压脑病; 脑组织血流量
Keywords:
 ; Keywords: three-dimensional arterial spin labeling perfusion imaging;  hypertensive encephalopathy;  cerebral blood flow
分类号:
R445.2；R318
DOI:
DOI:10.3969/j.issn.1005-202X.2019.09.011
文献标志码:
A
摘要:
 目的：使用3D动脉自旋标记（ASL）灌注成像对1级高血压患者的脑血流灌注进行定量分析，以探讨其应用价值。方法：对1级高血压患者组（36例）及非高血压健康对照组（14例）分别行常规MRI扫描及3D ASL灌注成像，并测量两组受检者17个特定脑区局部脑血流量（CBF）值，反映脑血流动力学参数，比较各脑区的灌注参数差异。结果：1级高血压组豆状核、丘脑、额上回、扣带回、额下回、额中回、半卵圆中心、中央前回，中央后回、颞叶、枕叶的灌注参数CBF值均比正常对照组低，其差异有统计学意义（P<0.05）；1级高血压组尾状核、杏仁核、侧脑室前后角灌注指标CBF值均与对照组无明显差异（P>0.05）。结论：3D ASL技术可发现1级高血压患者脑异常灌注情况，对防治高血压脑病有重要的价值。
Abstract:
 Abstract: Objective To quantitatively analyze the application of three-dimensional arterial spin labeling (3D ASL) perfusion imaging in patients with grade 1 hypertension and investigate its application value. Methods A total of 36 patients with grade 1 hypertension and 14 non-hypertension health controls were examined by routine magnetic resonance imaging and 3D ASL perfusion imaging. The local cerebral blood flow (CBF) values of 17 specific brain regions in two groups were measured to reflect the cerebral hemodynamic parameters, thereby comparing the differences of perfusion parameters in various regions. Results The CBF values of lentiform nucleus, thalamus, superior frontal gyrus, cingulate gyrus, inferior frontal gyrus, middle frontal gyrus, centrum semiovale, anterior central gyrus, posterior central gyrus, temporal lobe and occipital lobe in grade 1 hypertension group were lower than those in control group, with statistical differences (P<0.05). The CBF values of caudate nucleus, amygdaloid nucleus, anterior and posterior horns of lateral ventricle and corpus callosum were similar in grade 1 hypertension group and control group, without significant differences (P>0.05). Conclusion 3D ASL technique can be used to detect abnormal cerebral perfusion in patients with grade 1 hypertension, which is of great value in the prevention and treatment of hypertensive encephalopathy.

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备注/Memo

备注/Memo:
 【收稿日期】2019-04-15
【基金项目】陕西省社会发展基金项目（2017SF-001）
【作者简介】陈姗姗，硕士，主治医师，主要从事超声诊断工作，E-mail: 13659236535@163.com；高浪浪，技师，主要从事磁共振技术，E-mail: 545771278@qq.com
【通信作者】赵海涛，E-mail: zhaohaitao516@126.com；魏梦绮，E-mail: weimengqi2008@163.com
更新日期/Last Update: 2019-09-23