[1]刘小波,汪冬,赵云,等.KylinRay-IMRT与Pinnacle3胸部肿瘤计划剂量学比较分析[J].中国医学物理学杂志,2020,37(1):17-21.[doi:DOI:10.3969/j.issn.1005-202X.2020.01.004]
　LIU Xiaobo,WANG Dong,et al.Dosimetric comparison between KylinRay-IMRT and Pinnacle3 TPS in thoracic tumor plans[J].Chinese Journal of Medical Physics,2020,37(1):17-21.[doi:DOI:10.3969/j.issn.1005-202X.2020.01.004]
点击复制

KylinRay-IMRT与Pinnacle3胸部肿瘤计划剂量学比较分析()
分享到：

《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
37
期数:
2020年第1期
页码:
17-21
栏目:
医学放射物理
出版日期:
2020-01-25

文章信息/Info

Title:
Dosimetric comparison between KylinRay-IMRT and Pinnacle3 TPS in thoracic tumor plans
文章编号:
1005-202X（2020）01-0017-05
作者:
刘小波1; 2; 汪冬1; 赵云1; 郑华庆1; 贾婧1; 宋婧1
1.中国科学院核能安全技术研究所，中子输运理论与辐射安全重点实验室， 安徽 合肥 230031； 2.中国科学技术大学， 安徽 合肥 230026
Author(s):
LIU Xiaobo1;  2;  WANG Dong1;  ZHAO Yun1;  ZHENG Huaqing1;  JIA Jing1;  SONG Jing1
1. Key Laboratory of Neutronics and Radiation Safety, Institute of Nuclear Energy Safety Technology, Chinese Academy of Sciences, Hefei 230031, China; 2. University of Science and Technology of China, Hefei 230026, China
关键词:
调强放射治疗; 治疗计划系统; 软件测试; 剂量学; 计划比较
Keywords:
Keywords: intensity-modulated radiotherapy;  treatment planning system;  software test;  dosimetry;  plan comparison
分类号:
R811.1；R730.55
DOI:
DOI:10.3969/j.issn.1005-202X.2020.01.004
文献标志码:
A
摘要:
IMRT 5.0的逆向计划优化功能。方法：从例题库选取15例胸部例题并导入至调强放射治疗计划系统KylinRay-IMRT，在KylinRay-IMRT计划系统中进行优化计算并确认优化结果，从TPS提取剂量学指标值并记录，数据比较进行t检验。结果：两组TPS计划的靶区均匀性指数（HI）、适形度指数（CI）、剂量分布满足临床要求，KylinRay-IMRT计划在靶区HI上略优于对照TPS组（t=4.480；P=0.001）。KylinRay-IMRT计划肺的V10、V20、V30、平均剂量（t=2.594、6.672、3.471、6.225；P<0.05）略优于对照TPS组，心脏的V30、V40、平均剂量（t=6.078、6.466、8.712；P<0.05）明显优于对照TPS组。两组靶区CI（t=-1.548；P=0.144）、肺的V5（t=1.339；P=0.202）、脊髓最大剂量（t=1.465；P=0.165）无统计学意义。结论：对于胸部例题而言，由于TPS自身因素和人为因素导致两者计算结果存在差异，KylinRay-IMRT的计划质量在临床可接受的程度范围内，其逆向计划优化功能满足了临床应用的安全性和准确性要求。
Abstract:
Abstract: Objective To verify and evaluate the capability of inverse planning optimization of KylinRay-IMRT 5.0 for intensity-modulated radiotherapy (IMRT) by analyzing the quality of planning optimizations with two different treatment planning systems (TPS). Methods Fifteen thoracic tumor plans selected from case database were imported into KylinRay-IMRT for optimization calculations, and the optimization results were confirmed with those of Pinnacle3 TPS. The dosimetric index values selected from TPS were obtained and compared with t test. Results The homogeneity index, conformity index and dose distribution of two kinds of TPS plans satisfied the clinical requirements. The homogeneity index of target areas in KylinRay-IMRT plan was slightly better than that in control TPS plan (t=4.480; P=0.001). The V10, V20, V30 and mean dose of lungs in KylinRay-IMRT plan were slightly better than those in control TPS plan (t=2.594, 6.672, 3.471, 6.225; P<0.05), and the V30, V40 and mean dose of heart in KylinRay-IMRT plan were superior to those in control TPS plan (t=6.078, 6.466, 8.712; P<0.05). No statistical significance was found in the conformity index of target areas (t=-1.548; P=0.144), lung-V5 (t=1.339; P=0.202) and the maximum dose to spinal cord (t=1.465; P=0.165). Conclusion For cases of thoracic tumors, there are differences in the optimization outcomes of the two TPS due to TPS itself and human factors. The quality of KylinRay-IMRT plan is proved to be within the acceptable range, and its capability of inverse planning optimization satisfies the requirements of clinical safety and validity.

相似文献/References:

[1]史贵连,叶福丽.PTW729二维矩阵的平面剂量验证[J].中国医学物理学杂志,2015,32(02):239.[doi:10.3969/j.issn.1005-202X.2015.02.020]
[2]戴相昆,杨丰蔚,杜 镭,等.等效均匀剂量优化法在宫颈癌调强计划中的应用[J].中国医学物理学杂志,2015,32(02):290.[doi:10.3969/j.issn.1005-202X.2015.02.033]
[3]巩汉顺,王金媛,丛小虎,等.晚期胰腺癌适形、简化调强及螺旋断层放疗的剂量学评估[J].中国医学物理学杂志,2015,32(01):8.[doi:10.3969/j.issn.1005-202X.2015.01.003]
[4]曾 彪,张九堂,席许平,等.单中心上下半野技术在胸中上段食管癌放射治疗中的剂量学分布[J].中国医学物理学杂志,2015,32(03):357.[doi:10.3969/j.issn.1005-202X.2015.03.012]
[5]史贵连,叶福丽.肺癌调强放疗计划的设计[J].中国医学物理学杂志,2015,32(03):361.[doi:10.3969/j.issn.1005-202X.2015.03.013]
[6]陈炳周,路俊哲,侯 氢.不同设计方式的调强逆向治疗计划比较[J].中国医学物理学杂志,2015,32(03):391.[doi:10.3969/j.issn.1005-202X.2015.03.020]
[7]周 钢,田 野,陆雪官,等.同步加量技术应用于脑胶质瘤术后调强放疗的剂量学研究[J].中国医学物理学杂志,2014,31(02):4727.[doi:10.3969/j.issn.1005-202X.2014.02.002]
[8]宋 威,赵 迪,鹿 红,等.射野方向优化技术在胸中上段食管癌调强放疗中的应用[J].中国医学物理学杂志,2014,31(05):5109.[doi:10.3969/j.issn.1005-202X.2014.05.003]
[9]桑 勇,陈维军,狄小云,等.多叶光栅叶片宽度对鼻咽癌剂量学的影响[J].中国医学物理学杂志,2014,31(06):5240.[doi:10.3969/j.issn.1005-202X.2014.06.004]
[10]黄利生,庄婷婷,伍方财,等.鼻咽癌调强放疗Ib区剂量分析[J].中国医学物理学杂志,2014,31(06):5265.[doi:10.3969/j.issn.1005-202X.2014.06.010]

备注/Memo

备注/Memo:
【收稿日期】2019-06-14 【基金项目】国家自然科学基金（11605233）；中国科学院合肥物质科学研究院院长基金（YZJJ201618） 【作者简介】刘小波，主要研究方向：放射医学物理，E-mail: xiaobo.liu- @fds.org.cn 【通信作者】贾婧，副研究员，主要研究方向：医学物理，E-mail: jing.jia@fds.org.cn；宋婧，副研究员，主要研究方向：医学物理，E-mail: jing.song@fds.org.cn
更新日期/Last Update: 2020-01-14