[1]秦贺,刘波,喻大华.失眠患者大脑功能变化的磁共振影像学研究进展[J].中国医学物理学杂志,2018,35(9):1039-1042.[doi:10.3969/j.issn.1005-202X.2018.09.009]
　QIN He,LIU Bo,YUDahua.Advances in magnetic resonance imaging of changes in brain function in patients with insomnia[J].Chinese Journal of Medical Physics,2018,35(9):1039-1042.[doi:10.3969/j.issn.1005-202X.2018.09.009]
点击复制

失眠患者大脑功能变化的磁共振影像学研究进展()
分享到：

《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]

卷:
35卷
期数:
2018年第9期
页码:
1039-1042
栏目:
医学影像物理
出版日期:
2018-09-27

文章信息/Info

Title:
Advances in magnetic resonance imaging of changes in brain function in patients with insomnia
文章编号:
1005-202X（2018）09-1039-04
作者:
秦贺1; 刘波1; 喻大华2
1. 包头医学院第一附属医院神经内科，内蒙古包头014010；2. 内蒙古科技大学内蒙古自治区模式识别与智能图像处理重点实验室，内蒙古包头014010
Author(s):
QIN He1;  LIU Bo1;  YUDahua2
1. Department of Neurology, the First Affiliated Hospital of Baotou Medical College, Baotou 014010, China; 2. Inner Mongolia KeyLaboratory of Pattern Recognition and Intelligent Image Processing, Inner Mongolia University of Science and Technology, Baotou014010, China
关键词:
失眠; 大脑功能; 磁共振成像; 综述
Keywords:
Keywords: insomnia;  brain function;  magnetic resonance imaging;  review
分类号:
R338.2；R445.2
DOI:
10.3969/j.issn.1005-202X.2018.09.009
文献标志码:
A
摘要:
失眠的脑功能改变一般先于脑实质的改变，而功能磁共振（fMRI）可以在生理状态下无创地反映不同脑区各自的功能状态。本文从失眠的静息态和任务态大脑功能变化两个方面，对失眠的fMRI研究进展进行综述。利用fMRI发现，在静息态方面，失眠患者的一些脑区的局部一致性值、低频振幅值等出现异常，功能连接出现改变；而在任务态方面，失眠患者在执行认知任务时，任务相关脑区的激活出现低水平活化。本文通过了解失眠的发病机制，以期将fMRI技术应用于失眠的临床诊断。
Abstract:
Abstract: For patients with insomnia, the changes in brain function are generally earlier than the structural changes of brain,and functional magnetic resonance imaging (fMRI) is a non- invasively technology to reflect the functional status ofdifferent brain regions under physiological conditions. Herein the research progress of fMRI in insomnia is reviewed fromthe aspects of the changes in resting-state or task-state brain functions. In resting state, regional homogeneity and amplitudeof low-frequency fluctuation are found to be abnormal in several brain regions in patients with insomnia, and the functionalconnectivity is changed. When performing cognitive tasks, patients with insomnia show low-level activation of task-relatedbrain regions. This review may help us understand the pathogenesis of insomnia and strive to apply fMRI technology in theclinical diagnosis of insomnia.

相似文献/References:

[1]郑威,于洪丽,丁卫国,等. 基于格兰杰因果关系磁刺激穴位对亚健康失眠的脑功能网络分析[J].中国医学物理学杂志,2018,35(2):228.[doi:DOI:10.3969/j.issn.1005-202X.2018.02.022]
　ZHENG Wei,YU Hongli,DING Weiguo,et al. Brain functional network analysis of magnetic stimulation at acupoints for sub-health insomnia based on Granger causality[J].Chinese Journal of Medical Physics,2018,35(9):228.[doi:DOI:10.3969/j.issn.1005-202X.2018.02.022]

备注/Memo

备注/Memo:
【收稿日期】2018-05-26【基金项目】国家自然科学基金（81571753, 81571751）；内蒙古自治区高等学校青年科技英才支持计划（NJYT-17-B11）【作者简介】秦贺，研究生，住院医师，研究方向：失眠及成瘾的功能神经影像，E-mail: m18247264881@163.com【通信作者】刘波，硕士，主任医师，研究方向：脑血管病诊治、头晕头痛、睡眠障碍，E-mail: liu_bo2006@126.com；喻大华，博士，教授，研究方向：医学图像及信息处理技术，E-mail:fmydh@imust.edu.cn
更新日期/Last Update: 2018-09-28