Application of three-dimensional CT values in differential diagnosis of active and inactive pulmonary tuberculosis(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2025年第10期
- Page:
- 1337-1341
- Research Field:
- 医学影像物理
- Publishing date:
Info
- Title:
- Application of three-dimensional CT values in differential diagnosis of active and inactive pulmonary tuberculosis
- Author(s):
- ZHANG Zhifei; CHEN Rui; CAO Zonghua; ZHANG Quanwu; WANG Zhiyong; CHEN Xiaohui
- Imaging Center, Shaanxi Provincial Tuberculosis Prevention and Control Hospital (the Fifth Peoples Hospital of Shaanxi Provincial), Xian 710100, China
- Keywords:
- Keywords: active pulmonary tuberculosis inactive pulmonary tuberculosis three-dimensional CT value CT sign tuberculosis lesion differential diagnosis
- PACS:
- R521；R816.4
- DOI:
- DOI:10.3969/j.issn.1005-202X.2025.10.010
- Abstract:
- Abstract: Objective To explore the differential diagnostic value of three-dimensional CT values in active pulmonary tuberculosis (APTB) and inactive pulmonary tuberculosis (IPTB). Methods A retrospective analysis was conducted on 96 patients with pulmonary tuberculosis. According to whether the pulmonary tuberculosis lesions were active, the patients were divided into APTB group (n=61) and IPTB group (n=35). The baseline data, CT signs, and three-dimensional CT values were compared between two groups. Additionally, the results of three-dimensional CT values and conventional CT reading method in evaluating the activity of pulmonary tuberculosis were compared, and the accuracy, sensitivity and specificity of using three-dimensional CT values and conventional CT reading method to evaluate the activity of pulmonary tuberculosis were further analyzed. Results APTB group showed a higher incidence of bilateral pulmonary lesions than IPTB group (P<0.05). Compared with IPTB group, APTB group had higher proportions of blurred boundaries, parenchymal cavities, ground-glass opacities, and tree-in-bud signs (P<0.05), but lower proportions of parenchymal bronchiectasis, parenchymal calcifications, and fibrous strip shadows (P<0.05). The three-dimensional CT values in APTB group were lower than those in IPTB group (P<0.05). Significant differences were observed between conventional CT reading method and three-dimensional CT values in evaluating the activities of pulmonary parenchymal calcifications and thick-wall cavities (P<0.05). Specifically, three-dimensional CT values correctly identified 92 cases of tuberculosis lesions, including 59 cases of APTB and 33 cases of IPTB, and the remaining 4 misidentified lesions were calcified, consolidated and nodular lesions. Conventional CT reading method correctly identified 68 cases of tuberculosis lesions, including 43 cases of APTB and 25 cases of IPTB. The sensitivity, specificity, and accuracy of three-dimensional CT values were all higher than those of conventional CT reading method (P<0.05). Conclusion Three-dimensional CT values can effectively determine the activity of pulmonary tuberculosis, exhibiting high sensitivity, specificity, and accuracy.
Last Update: 2025-10-29