Abstract

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Title:: Effect of aortic stenosis on blood flow characteristics in the left ventricle

Author(s):: QIANG Yan1; 2; LI Zhixiong1; HAN Wei1; LI Rennian1; FENG Huimin1; MA Xiaoning1; ZHANG Sicong1; 1. College of Energy and Power Engineering, Lanzhou University of Technology, Lanzhou 730050, China 2. School of Energy and Environment, Southeast University, Nanjing 210096, China

Keywords:: Keywords: left ventricle aortic stenosis hydraulic radius blood flow characteristic shear stress

Abstract:: Abstract: The 3D model of the left ventricle is reconstructed and optimized based on CT scan data. In combination with the motion characteristics of myocardium wall, the mathematical models of left ventricular wall motions are established. The degree of aortic stenosis is characterized by hydraulic radius, and the moving grid technique is used to explore the effect of aortic stenosis on left ventricular blood flow. It is found that hydraulic radius is negatively correlated with the degree of aortic stenosis. The decreased outlet area results in higher velocity and pressure at the outlet in systole and increasing shear stress. During diastole, the velocity and pressure increase first and then decrease. With small hydraulic radius, the shear stress at the left ventricular valve is larger, and the maximum shear stress at the initial stage of contraction is 0.81 Pa. The dynamic simulation of the heart provides significant reference for the subsequent research on the heart.