Spectral CT findings of peripheral lung adenocarcinoma and peripheral lung squamous cell
carcinoma(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2021年第9期
- Page:
- 1097-1102
- Research Field:
- 医学影像物理
- Publishing date:
Info
- Title:
- Spectral CT findings of peripheral lung adenocarcinoma and peripheral lung squamous cell
carcinoma
- Author(s):
- DENG Liangna1; 2; 3; ZHANG Guojin1; 2; 3; ZHANG Bin1; 2; 3; JING Mengyuan1; 2; 3; HAN Tao1; 2; 3; LIN Xiaoqiang1; 2; 3; ZHOU Junlin1; 2; 3
- 1. Department of Radiology, Lanzhou University Second Hospital, Lanzhou 730030, China 2. the Second School of Clinical Medicine,
Lanzhou University, Lanzhou 730000, China 3. Key Laboratory of Medical Imaging in Gansu Province, Lanzhou 730030, China
- Keywords:
- lung cancer spectral CT lung squamous cell carcinoma lung adenocarcinoma differential diagnosis
- PACS:
- R734.2；R816.41
- DOI:
- 10.3969/j.issn.1005-202X.2021.09.009
- Abstract:
- Objective To compare the spectral computed tomography (CT) findings of peripheral lung adenocarcinoma versus
peripheral lung squamous cell carcinoma. Methods A total of 122 cases of peripheral lung adenocarcinoma and 89 cases of
peripheral lung squamous cell carcinoma were analyzed retrospectively.All of these cases were proved by pathology and received
energy spectral CT examination. The CT40 keV, CT70 keV, CT100 keV, iodine (water) concentration (IC), water (iodine) concentration (WC)
and effective atomic number (Zeff) were measured in the arterial phase and the venous phase, and the slope of spectral curve (K70 keV)
was calculated. The differences of spectral parameters between two groups were compared. Results There was no significant
difference between two groups in clinical features and symptoms (P>0.05) except gender (P<0.05). In the arterial phase and the
venous phase, the CT40 keV, CT70 keV, K70 keV, IC and Zeff of peripheral lung adenocarcinoma were higher than those of peripheral lung
squamous cell carcinoma, with statistical differences (P<0.05), but no significant difference was found inWC and CT100 keV between
two groups (P>0.05). Receiver operating characteristic curve analysis showed that the combination of quantitative parameters
in the arterial phase had better diagnostic efficiency than the combination of quantitative parameters in the venous phase, and that
the area under the curve, sensitivity and specificity of the former were 86%, 77%, and 83%, respectively. Conclusion There are
some differences in spectral CT findings between peripheral lung adenocarcinoma and peripheral lung squamous cell carcinoma,
which can provide reference for the differential diagnosis.
Last Update: 2021-09-27