Coplanar volumetric modulated arc therapy plan for hippocampal avoidance whole?rain radiotherapy implemented on a Halcyon linear accelerator(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2026年第7期
- Page:
- 841-846
- Research Field:
- 医学放射物理
- Publishing date:
Info
- Title:
- Coplanar volumetric modulated arc therapy plan for hippocampal avoidance whole?rain radiotherapy implemented on a Halcyon linear accelerator
- Author(s):
- FANG Yalan1; DENG Guanhua2; TANG Ran3; LAN Maoying4; LUO Rishun5
- 1. Outpatient Department, Sun Yat-sen University Cancer Center, Guangzhou 510060, China 2. Department of Radiation Oncology, Guangdong Provincial Peoples Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou 510080, China 3. Department of Radiation Oncology, the Affiliated Huizhou Hospital of Guangzhou Medical University, Huizhou 516000, China 4. Department of Radiation Oncology, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou 510163, China 5. Department of Oncology, Guangdong Sanjiu Brain Hospital, Guangzhou 510510, China
- Keywords:
- Halcyon accelerator hippocampus avoidance whole-brain radiotherapy volumetric modulated arc therapy
- PACS:
- R318；R811.1
- DOI:
- DOI:10.3969/j.issn.1005-202X.2026.07.001
- Abstract:
- Objective To compare the dosimetric differences among Varian Halcyon, TrueBeam, and United Imaging uRT-506c linear accelerator in hippocampal avoidance whole?rain radiotherapy. Methods A retrospective analysis was conducted on 15 patients who had previously received hippocampal avoidance whole-brain volumetric modulated arc therapy (VMAT). Dual-arc coplanar VMAT plans were created using the Halcyon, TrueBeam, and uRT-506c accelerator models, with collimator angles of 23° and 293°, respectively. Based on the position of the hippocampus, the whole-brain target volume was divided into 3 substructures (zPTV_up, zPTV_mid, and zPTV_down), each optimized using different weight factors. The dosimetric parameters of the planning target volume, organ-at-risk doses, and monitor unit in the 3 groups were recorded and analyzed. Results VMAT plans for all patients satisfied clinical treatment criteria. Halcyon plans were superior to True Beam and uRT-506c plans in the D2%, V30 Gy, and HI of planning target volume, the D100%, Dmean, and Dmax of the hippocampus, as well as the Dmax of the lens and optic nerves, with statistically significant differences (P<0.05). Conclusion For hippocampus avoidance whole-brain radiotherapy, the Halcyon linear accelerator delivers superior dose distribution and robust plan calculation results, and its ring gantry ensures efficient treatment delivery while highlighting the strengths of precise radiotherapy, showing great potential for clinical practice.
Last Update: 2026-07-22