Diagnostic efficacy of combined multi-parameter ultrasound for detecting fetal growth restriction in pregnancies complicated with gestational diabetes mellitus(PDF)
《中国医学物理学杂志》[ISSN:1005-202X/CN:44-1351/R]
- Issue:
- 2026年第6期
- Page:
- 782-786
- Research Field:
- 医学影像物理
- Publishing date:
Info
- Title:
- Diagnostic efficacy of combined multi-parameter ultrasound for detecting fetal growth restriction in pregnancies complicated with gestational diabetes mellitus
- Author(s):
- WANG Liangqin; LAI Liping; HE Mingyu; XIAO Xiaoqing
- Department of Ultrasound, Longyan First Hospital Affiliated to Fujian Medical University, Longyan 364000, China
- Keywords:
- Keywords: gestational diabetes mellitus pregnant woman fetal growth restriction umbilical artery color Doppler flow imaging ultrasonic growth parameter
- PACS:
- R445.1；R714.5
- DOI:
- DOI:10.3969/j.issn.1005-202X.2026.06.011
- Abstract:
- Abstract: Objective To evaluate the diagnostic performance of single and combined ultrasonic parameters, including umbilical artery systolic/diastolic velocity ratio (S/D ratio) and Z-scores of fetal ultrasonic growth parameters (biparietal diameter, abdominal circumference, femur length), for the detection of fetal growth restriction (FGR) in pregnant women with gestational diabetes mellitus (GDM). Methods A total of 120 pregnant women with GDM who registered for prenatal check-ups and admitted for delivery at the Department of Obstetrics and Gynecology, Longyan First Hospital Affiliated to Fujian Medical University between July 2024 and May 2025 were enrolled as study subjects. According to neonatal birth weight and serial prenatal ultrasound follow-up results, those with a fetal birth weight below the 10th percentile for the corresponding gestational age were included in the FGR group (n=32), and the remaining were included in the non-FGR group (n=88). The fasting blood glucose, amniotic fluid index, age, gestational weeks, pre-pregnancy BMI, neonatal Apgar score, and other clinical routine data were recorded. Meanwhile, the umbilical artery S/D ratio and ultrasonic growth parameters were collected. Differences in these indicators were compared, and the diagnostic sensitivity of different indicators for FGR was calculated. Results Compared with the non-FGR group, the FGR group demonstrated a higher umbilical artery S/D ratio and lower Z-scores of ultrasonic growth parameters (all P<0.05). ROC curve analysis showed that the umbilical artery S/D ratio alone had an AUC of 0.852, with a sensitivity of 81.25% and a specificity of 79.55% for diagnosing FGR among pregnant women with GDM. The combination of the Z-scores of ultrasonic growth parameters obtained an AUC of 0.896, sensitivity of 87.50%, and specificity of 84.09%. The umbilical artery S/D ratio combined with Z-scores of ultrasonic growth parameters achieved an AUC, sensitivity, and specificity of 0.926, 90.63%, and 88.64%, respectively. Conclusion The combination of the umbilical-artery S/D ratio and Z-scores of ultrasonic growth parameters significantly improves the diagnostic performance for FGR in pregnancies complicated with GDM. By integrating hemodynamic and morphometric information, this assessment scheme provides a superior objective sonographic basis for the early identification of FGR.
Last Update: 2026-06-29